An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease von Horvath, Steve, Gurven, Michael, Levine, Morgan E, Trumble, Benjamin C, Kaplan, Hillard, Allayee, Hooman, Ritz, Beate R, Chen, Brian, Lu, Ake T, Rickabaugh, Tammy M, Jamieson, Beth D, Sun, Dianjianyi, Li, Shengxu, Chen, Wei, Quintana-Murci, Lluis, Fagny, Maud, Kobor, Michael S, Tsao, Philip S, Reiner, Alexander P, Edlefsen, Kerstin L, Absher, Devin, Assimes, Themistocles L

Volltext

GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality von McCrory, Cathal, Fiorito, Giovanni, Hernandez, Belinda, Polidoro, Silvia, O’Halloran, Aisling M, Hever, Ann, Ni Cheallaigh, Cliona, Lu, Ake T, Horvath, Steve, Vineis, Paolo, Kenny, Rose Anne

Volltext

DNA methylation GrimAge strongly predicts lifespan and healthspan von Lu, Ake T, Quach, Austin, Wilson, James G, Reiner, Alex P, Aviv, Abraham, Raj, Kenneth, Hou, Lifang, Baccarelli, Andrea A, Li, Yun, Stewart, James D, Whitsel, Eric A, Assimes, Themistocles L, Ferrucci, Luigi, Horvath, Steve

Volltext

Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning von Levine, Morgan E, Lu, Ake T, Bennett, David A, Horvath, Steve

Volltext

A mammalian methylation array for profiling methylation levels at conserved sequences von Arneson, Adriana, Haghani, Amin, Thompson, Michael J., Pellegrini, Matteo, Kwon, Soo Bin, Vu, Ha, Maciejewski, Emily, Yao, Mingjia, Li, Caesar Z., Lu, Ake T., Morselli, Marco, Rubbi, Liudmilla, Barnes, Bret, Hansen, Kasper D., Zhou, Wanding, Breeze, Charles E., Ernst, Jason, Horvath, Steve

Volltext

Detection of Macular Ganglion Cell Loss in Glaucoma by Fourier-Domain Optical Coherence Tomography von Tan, Ou, PhD, Chopra, Vikas, MD, Lu, Ake Tzu-Hui, PhD, Schuman, Joel S., MD, Ishikawa, Hiroshi, MD, Wollstein, Gadi, MD, Varma, Rohit, MD, MPH, Huang, David, MD, PhD

Volltext

Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies von Horvath, Steve, Oshima, Junko, Martin, George M, Lu, Ake T, Quach, Austin, Cohen, Howard, Felton, Sarah, Matsuyama, Mieko, Lowe, Donna, Kabacik, Sylwia, Wilson, James G, Reiner, Alex P, Maierhofer, Anna, Flunkert, Julia, Aviv, Abraham, Hou, Lifang, Baccarelli, Andrea A, Li, Yun, Stewart, James D, Whitsel, Eric A, Ferrucci, Luigi, Matsuyama, Shigemi, Raj, Kenneth

Volltext

Fundamental equations linking methylation dynamics to maximum lifespan in mammals von Horvath, Steve, Zhang, Joshua, Haghani, Amin, Lu, Ake T., Fei, Zhe

Volltext

A meta-analysis of genome-wide association studies of epigenetic age acceleration von Gibson, Jude, Russ, Tom C, Clarke, Toni-Kim, Howard, David M, Hillary, Robert F, Evans, Kathryn L, Walker, Rosie M, Bermingham, Mairead L, Morris, Stewart W, Campbell, Archie, Hayward, Caroline, Murray, Alison D, Porteous, David J, Horvath, Steve, Lu, Ake T, McIntosh, Andrew M, Whalley, Heather C, Marioni, Riccardo E

Volltext

Menopause accelerates biological aging von Levine, Morgan E., Lu, Ake T., Chen, Brian H., Hernandez, Dena G., Singleton, Andrew B., Ferrucci, Luigi, Bandinelli, Stefania, Salfati, Elias, Manson, JoAnn E., Quach, Austin, Kusters, Cynthia D. J., Kuh, Diana, Wong, Andrew, Teschendorff, Andrew E., Widschwendter, Martin, Ritz, Beate R., Absher, Devin, Assimes, Themistocles L., Horvath, Steve

Volltext

An epigenetic biomarker of aging for lifespan and healthspan von Levine, Morgan E, Lu, Ake T, Quach, Austin, Chen, Brian H, Assimes, Themistocles L, Bandinelli, Stefania, Hou, Lifang, Baccarelli, Andrea A, Stewart, James D, Li, Yun, Whitsel, Eric A, Wilson, James G, Reiner, Alex P, Aviv, Abraham, Lohman, Kurt, Liu, Yongmei, Ferrucci, Luigi, Horvath, Steve

Volltext

Epigenetic clock analysis of diet, exercise, education, and lifestyle factors von Quach, Austin, Levine, Morgan E, Tanaka, Toshiko, Lu, Ake T, Chen, Brian H, Ferrucci, Luigi, Ritz, Beate, Bandinelli, Stefania, Neuhouser, Marian L, Beasley, Jeannette M, Snetselaar, Linda, Wallace, Robert B, Tsao, Philip S, Absher, Devin, Assimes, Themistocles L, Stewart, James D, Li, Yun, Hou, Lifang, Baccarelli, Andrea A, Whitsel, Eric A, Horvath, Steve

Volltext

Keratoconus Diagnosis with Optical Coherence Tomography Pachymetry Mapping von Li, Yan, PhD, Meisler, David M., MD, Tang, Maolong, PhD, Lu, Ake T.H., PhD, Thakrar, Vishakha, MD, Reiser, Bibiana J., MD, Huang, David, MD, PhD

Volltext

Refining epigenetic prediction of chronological and biological age von Bernabeu, Elena, McCartney, Daniel L, Gadd, Danni A, Hillary, Robert F, Lu, Ake T, Murphy, Lee, Wrobel, Nicola, Campbell, Archie, Harris, Sarah E, Liewald, David, Hayward, Caroline, Sudlow, Cathie, Cox, Simon R, Evans, Kathryn L, Horvath, Steve, McIntosh, Andrew M, Robinson, Matthew R, Vallejos, Catalina A, Marioni, Riccardo E

Volltext

Significant variation in the performance of DNA methylation predictors across data preprocessing and normalization strategies von Ori, Anil P S, Lu, Ake T, Horvath, Steve, Ophoff, Roel A

Volltext

Genetic architecture of epigenetic and neuronal ageing rates in human brain regions von Lu, Ake T., Hannon, Eilis, Levine, Morgan E., Crimmins, Eileen M., Lunnon, Katie, Mill, Jonathan, Geschwind, Daniel H., Horvath, Steve

Volltext

Biological age is increased by stress and restored upon recovery von Poganik, Jesse R., Zhang, Bohan, Baht, Gurpreet S., Tyshkovskiy, Alexander, Deik, Amy, Kerepesi, Csaba, Yim, Sun Hee, Lu, Ake T., Haghani, Amin, Gong, Tong, Hedman, Anna M., Andolf, Ellika, Pershagen, Göran, Almqvist, Catarina, Clish, Clary B., Horvath, Steve, White, James P., Gladyshev, Vadim N.

Volltext

Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation von Horvath, Steve, Lu, Ake T, Cohen, Howard, Raj, Ken

Volltext

DNA methylation study of Huntington’s disease and motor progression in patients and in animal models von Lu, Ake T., Narayan, Pritika, Grant, Matthew J., Langfelder, Peter, Wang, Nan, Kwak, Seung, Wilkinson, Hilary, Chen, Richard Z., Chen, Jian, Simon Bawden, C., Rudiger, Skye R., Ciosi, Marc, Chatzi, Afroditi, Maxwell, Alastair, Hore, Timothy A., Aaronson, Jeff, Rosinski, Jim, Preiss, Alicia, Vogt, Thomas F., Coppola, Giovanni, Monckton, Darren, Snell, Russell G., William Yang, X., Horvath, Steve

Volltext

Mapping of Macular Substructures with Optical Coherence Tomography for Glaucoma Diagnosis von Tan, Ou, PhD, Li, Gisèle, MD, Lu, Ake Tzu-Hui, PhD, Varma, Rohit, MD, MPH, Huang, David, MD, PhD

Volltext