Molecular Pathways: Metabolic Control of Histone Methylation and Gene Expression in Cancer von Tran, Thai Q, Lowman, Xazmin H, Kong, Mei

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MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1 von Yang, Ying, Ishak Gabra, Mari B., Hanse, Eric A., Lowman, Xazmin H., Tran, Thai Q., Li, Haiqing, Milman, Neta, Liu, Juan, Reid, Michael A., Locasale, Jason W., Gil, Ziv, Kong, Mei

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Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth von Ishak Gabra, Mari B., Yang, Ying, Li, Haiqing, Senapati, Parijat, Hanse, Eric A., Lowman, Xazmin H., Tran, Thai Q., Zhang, Lishi, Doan, Linda T., Xu, Xiangdong, Schones, Dustin E., Fruman, David A., Kong, Mei

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Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes von Tran, Thai Q, Ishak Gabra, Mari B, Lowman, Xazmin H, Yang, Ying, Reid, Michael A, Pan, Min, O'Connor, Timothy R, Kong, Mei

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p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake von Lowman, Xazmin H., Hanse, Eric A., Yang, Ying, Ishak Gabra, Mari B., Tran, Thai Q., Li, Haiqing, Kong, Mei

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Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation von Pan, Min, Reid, Michael A., Lowman, Xazmin H., Kulkarni, Rajan P., Tran, Thai Q., Liu, Xiaojing, Yang, Ying, Hernandez-Davies, Jenny E., Rosales, Kimberly K., Li, Haiqing, Hugo, Willy, Song, Chunying, Xu, Xiangdong, Schones, Dustin E., Ann, David K., Gradinaru, Viviana, Lo, Roger S., Locasale, Jason W., Kong, Mei

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The B56α subunit of PP2A is necessary for mesenchymal stem cell commitment to adipocyte von Hanse, Eric A, Pan, Min, Liu, Wenzhu, Yang, Ying, Ishak Gabra, Mari B, Tran, Thai Q, Lowman, Xazmin H, Ruiz, Bryan, Wang, Qiong A, Kong, Mei

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The Proapoptotic Function of Noxa in Human Leukemia Cells Is Regulated by the Kinase Cdk5 and by Glucose von Lowman, Xazmin H., McDonnell, Maureen A., Kosloske, Ashley, Odumade, Oludare A., Jenness, Christopher, Karim, Christine B., Jemmerson, Ronald, Kelekar, Ameeta

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α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer von Tran, Thai Q, Hanse, Eric A, Habowski, Amber N, Li, Haiqing, Ishak Gabra, Mari B, Yang, Ying, Lowman, Xazmin H, Ooi, Amelia M, Liao, Shu Y, Edwards, Robert A, Waterman, Marian L, Kong, Mei

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IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3 von Reid, Michael A, Lowman, Xazmin H, Pan, Min, Tran, Thai Q, Warmoes, Marc O, Ishak Gabra, Mari B, Yang, Ying, Locasale, Jason W, Kong, Mei

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Alpha-Ketoglutarate Regulates Tnfrsf12a/Fn14 Expression via Histone Modification and Prevents Cancer-Induced Cachexia von Ruiz, Bryan I, Lowman, Xazmin H, Yang, Ying, Fan, Qi, Wang, Tianhong, Wu, Hongmei, Hanse, Eric A, Kong, Mei

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IKKβ activates p53 to promote cancer cell adaptation to glutamine deprivation von Ishak Gabra, Mari B., Yang, Ying, Lowman, Xazmin H., Reid, Michael A., Tran, Thai Q., Kong, Mei

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TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response von Rosales, Kimberly Romero, Reid, Michael A, Yang, Ying, Tran, Thai Q, Wang, Wen-I, Lowman, Xazmin, Pan, Min, Kong, Mei

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Vemurafenib resistance reprograms melanoma cells towards glutamine dependence von Hernandez-Davies, Jenny E, Tran, Thai Q, Reid, Michael A, Rosales, Kimberly R, Lowman, Xazmin H, Pan, Min, Moriceau, Gatien, Yang, Ying, Wu, Jun, Lo, Roger S, Kong, Mei

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Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer von Hanse, E A, Ruan, C, Kachman, M, Wang, D, Lowman, X H, Kelekar, A

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Tumor-associated mutant p53 promotes cancer cell survival upon glutamine deprivation through p21 induction von Tran, T Q, Lowman, X H, Reid, M A, Mendez-Dorantes, C, Pan, M, Yang, Y, Kong, M

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Sleep and non-invasive ventilation in patients with chronic respiratory insufficiency von Ambrogio, Cristina, Lowman, Xazmin, Kuo, Ming, Malo, Joshua, Prasad, Anil R., Parthasarathy, Sairam

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A role for Noxa in human primary T cell activation and metabolic reprogramming (LYM4P.756) von Benson, Jenna, Lowman, Xazmin, Hanse, Eric, Kelekar, Ameeta

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Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4 H -chromene-3-carboxylate (CXL017): A Novel Scaffold That Resensitizes Multidrug Resistant Leukemia Cells to Chemoth... von Das, Sonia G., Hermanson, David L., Bleeker, Nicholas, Lowman, Xazmin, Li, Yunfang, Kelekar, Ameeta, Xing, Chengguo

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Ethyl 2‑Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)‑4H‑chromene-3-carboxylate (CXL017): A Novel Scaffold That Resensitizes Multidrug Resistant Leukemia Cells to Chemother... von Das, Sonia G, Hermanson, David L, Bleeker, Nicholas, Lowman, Xazmin, Li, Yunfang, Kelekar, Ameeta, Xing, Chengguo

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