Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index von Junutula, Jagath R, Mallet, William, Raab, Helga, Clark, Suzanna, Bhakta, Sunil, Leipold, Douglas D, Weir, Sylvia, Chen, Yvonne, Simpson, Michelle, Tsai, Siao Ping, Dennis, Mark S, Lu, Yanmei, Meng, Y Gloria, Ng, Carl, Yang, Jihong, Lee, Chien C, Duenas, Eileen, Gorrell, Jeffrey, Katta, Viswanatham, Kim, Amy, McDorman, Kevin, Flagella, Kelly, Venook, Rayna, Ross, Sarajane, Spencer, Susan D, Lee Wong, Wai, Lowman, Henry B, Vandlen, Richard, Sliwkowski, Mark X, Scheller, Richard H, Polakis, Paul

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Engineering Human IgG1 Affinity to Human Neonatal Fc Receptor: Impact of Affinity Improvement on Pharmacokinetics in Primates von Yeung, Yik Andy, Leabman, Maya K, Marvin, Jonathan S, Qiu, Julia, Adams, Camellia W, Lien, Samantha, Starovasnik, Melissa A, Lowman, Henry B

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Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs von Junutula, Jagath R., Bhakta, Sunil, Raab, Helga, Ervin, Karen E., Eigenbrot, Charles, Vandlen, Richard, Scheller, Richard H., Lowman, Henry B.

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Widespread monoclonal IgE antibody convergence to an immunodominant, proanaphylactic Ara h 2 epitope in peanut allergy von Croote, Derek, Wong, Joyce J W, Pecalvel, Cyprien, Leveque, Edouard, Casanovas, Natacha, Kamphuis, Jasper B J, Creeks, Paige, Romero, Johanna, Sohail, Saba, Bedinger, Daniel, Nadeau, Kari C, Chinthrajah, Rebecca S, Reber, Laurent L, Lowman, Henry B

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Preclinical efficacy of peanut-specific IgG4 antibody therapeutic IGNX001 von Croote, Derek, Wong, Joyce J.W., Creeks, Paige, Aruva, Venu, Landers, Jeffrey J., Kwok, Matthew, Jama, Zainab, Hamilton, Robert G., Santos, Alexandra F., O’Konek, Jessica J., Ferrini, Roger, Thomas, G. Roger, Lowman, Henry B.

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Therapeutic peptides von Lien, Samantha, Lowman, Henry B

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VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface von Muller, Yves A, Chen, Yvonne, Christinger, Hans W, Li, Bing, Cunningham, Brian C, Lowman, Henry B, de Vos, Abraham M

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Nanoparticle Formulation Derived from Carboxymethyl Cellulose, Polyethylene Glycol, and Cabazitaxel for Chemotherapy Delivery to the Brain von Bteich, Joseph, Ernsting, Mark J, Mohammed, Mohammed, Kiyota, Taira, McKee, Trevor D, Trikha, Mohit, Lowman, Henry B, Sokoll, Kenneth K

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Evaluation of IgE Antibodies to Omalizumab (Xolair®) and Their Potential Correlation to Anaphylaxis von Baker, Dana L., Nakamura, Gerald R., Lowman, Henry B., Fischer, Saloumeh Kadkhodayan

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Pharmacokinetics of Humanized Monoclonal Anti-Tumor Necrosis Factor-α Antibody and Its Neonatal Fc Receptor Variants in Mice and Cynomolgus Monkeys von RONG DENG, LOYET, Kelly M, LIEN, Samantha, LYER, Suhasini, DEFORGE, Laura E, THEIL, Frank-Peter, LOWMAN, Henry B, FIELDER, Paul J, PRABHU, Saileta

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Stable "Zeta" Peptides That Act as Potent Antagonists of the High-Affinity IgE Receptor von Nakamura, Gerald R., Reynolds, Mark E., Chen, Yvonne M., Starovasnik, Melissa A., Lowman, Henry B.

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A therapeutic anti-VEGF antibody with increased potency independent of pharmacokinetic half-life von Yeung, Yik Andy, Wu, Xiumin, Reyes, 2nd, Arthur E, Vernes, Jean-Michel, Lien, Samantha, Lowe, John, Maia, Mauricio, Forrest, William F, Meng, Y Gloria, Damico, Lisa A, Ferrara, Napoleone, Lowman, Henry B

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Increases in Free, Unbound Insulin-like Growth Factor I Enhance Insulin Responsiveness in Human Hepatoma G2 Cells in Culture von Sakai, Keiji, Lowman, Henry B., Clemmons, David R.

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FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family von Holcomb, Ilona N., Kabakoff, Rhona C., Chan, Betty, Baker, Thad W., Gurney, Austin, Henzel, William, Nelson, Chris, Lowman, Henry B., Wright, Barbara D., Skelton, Nicholas J., Frantz, Gretchen D., Tumas, Daniel B., Peale, Jr, Franklin V., Shelton, David L., Hébert, Caroline C.

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[21] Phage display for selection of novel binding peptides von Sidhu, Sachdev S., Lowman, Henry B., Cunningham, Brian C., Wells, James A.

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Convergent Recognition of the IgE Binding Site on the High-Affinity IgE Receptor von Stamos, Jennifer, Eigenbrot, Charles, Nakamura, Gerald R, Reynolds, Mark E, Yin, JianPing, Lowman, Henry B, Fairbrother, Wayne J, Starovasnik, Melissa A

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Molecular Mimics of Insulin-like Growth Factor 1 (IGF-1) for Inhibiting IGF-1:  IGF-Binding Protein Interactions von Lowman, Henry B, Chen, Yvonne M, Skelton, Nicholas J, Mortensen, Deborah L, Tomlinson, Elizabeth E, Sadick, Michael D, Robinson, Iain C. A. F, Clark, Ross G

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Redesigning an Antibody Fragment for Faster Association with Its Antigen von Marvin, Jonathan S., Lowman, Henry B.

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Technology comparisons for anti-therapeutic antibody and neutralizing antibody assays in the context of an anti-TNF pharmacokinetic study von Loyet, Kelly M., Deng, Rong, Liang, Wei-Ching, Wu, Yan, Lowman, Henry B., DeForge, Laura E.

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Affinity Maturation of Human Growth Hormone by Monovalent Phage Display von Lowman, Henry B., Wells, James A.

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