Novel, provable algorithms for efficient ensemble-based computational protein design and their application to the redesign of the c-Raf-RBD:KRas protein-protein interface von Lowegard, Anna U., Frenkel, Marcel S., Holt, Graham T., Jou, Jonathan D., Ojewole, Adegoke A., Donald, Bruce R.

Volltext

Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design von Holt, Graham T., Gorman, Jason, Wang, Siyu, Lowegard, Anna U., Zhang, Baoshan, Liu, Tracy, Lin, Bob C., Louder, Mark K., Frenkel, Marcel S., McKee, Krisha, O’Dell, Sijy, Rawi, Reda, Shen, Chen-Hsiang, Doria-Rose, Nicole A., Kwong, Peter D., Donald, Bruce R.

Volltext

OSPREY 3.0: Open‐source protein redesign for you, with powerful new features von Hallen, Mark A., Martin, Jeffrey W., Ojewole, Adegoke, Jou, Jonathan D., Lowegard, Anna U., Frenkel, Marcel S., Gainza, Pablo, Nisonoff, Hunter M., Mukund, Aditya, Wang, Siyu, Holt, Graham T., Zhou, David, Dowd, Elizabeth, Donald, Bruce R.

Volltext

Early computational detection of potential high-risk SARS-CoV-2 variants von Beguir, Karim, Skwark, Marcin J., Fu, Yunguan, Pierrot, Thomas, Carranza, Nicolas Lopez, Laterre, Alexandre, Kadri, Ibtissem, Korched, Abir, Lowegard, Anna U., Lui, Bonny Gaby, Sänger, Bianca, Liu, Yunpeng, Poran, Asaf, Muik, Alexander, Şahin, Uğur

Volltext

Minimization-Aware Recursive K: A Novel, Provable Algorithm that Accelerates Ensemble-Based Protein Design and Provably Approximates the Energy Landscape von Jou, Jonathan D., Holt, Graham T., Lowegard, Anna U., Donald, Bruce R.

Volltext

Computational Analysis of Energy Landscapes Reveals Dynamic Features That Contribute to Binding of Inhibitors to CFTR-Associated Ligand von Holt, Graham T, Jou, Jonathan D, Gill, Nicholas P, Lowegard, Anna U, Martin, Jeffrey W, Madden, Dean R, Donald, Bruce R

Volltext

NOVEL ANTIBODIES FOR HIV AND METHODS OF MAKING AND USING THE SAME von GORMAN, Jason, KWONG, Peter, DORIA-ROSE, Nicole, CHUANG, Gwo Yu, LOWEGARD, Anna U, WANG, Siyu, HOLT, Graham T, FRENKEL, Marcel S, DONALD, Bruce R

Volltext bestellen

Minimization-Aware Recursive K∗\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{ma... von Jou, Jonathan D., Holt, Graham T., Lowegard, Anna U., Donald, Bruce R.

Volltext