Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway von Freed-Pastor, William A., Mizuno, Hideaki, Zhao, Xi, Langerød, Anita, Moon, Sung-Hwan, Rodriguez-Barrueco, Ruth, Barsotti, Anthony, Chicas, Agustin, Li, Wencheng, Polotskaia, Alla, Bissell, Mina J., Osborne, Timothy F., Tian, Bin, Lowe, Scott W., Silva, Jose M., Børresen-Dale, Anne-Lise, Levine, Arnold J., Bargonetti, Jill, Prives, Carol

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p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells von Iannello, Alexandre, Thompson, Thornton W, Ardolino, Michele, Lowe, Scott W, Raulet, David H

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Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks von Schneider, William M., Luna, Joseph M., Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Leal, Andrew A., Ashbrook, Alison W., Le Pen, Jérémie, Ricardo-Lax, Inna, Michailidis, Eleftherios, Peace, Avery, Stenzel, Ansgar F., Lowe, Scott W., MacDonald, Margaret R., Rice, Charles M., Poirier, John T.

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Non-Cell-Autonomous Tumor Suppression by p53 von Lujambio, Amaia, Akkari, Leila, Simon, Janelle, Grace, Danielle, Tschaharganeh, Darjus F., Bolden, Jessica E., Zhao, Zhen, Thapar, Vishal, Joyce, Johanna A., Krizhanovsky, Valery, Lowe, Scott W.

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A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference von Premsrirut, Prem K., Dow, Lukas E., Kim, Sang Yong, Camiolo, Matthew, Malone, Colin D., Miething, Cornelius, Scuoppo, Claudio, Zuber, Johannes, Dickins, Ross A., Kogan, Scott C., Shroyer, Kenneth R., Sordella, Raffaella, Hannon, Gregory J., Lowe, Scott W.

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Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53 von Bywater, Megan J., Poortinga, Gretchen, Sanij, Elaine, Hein, Nadine, Peck, Abigail, Cullinane, Carleen, Wall, Meaghan, Cluse, Leonie, Drygin, Denis, Anderes, Kenna, Huser, Nanni, Proffitt, Chris, Bliesath, Joshua, Haddach, Mustapha, Schwaebe, Michael K., Ryckman, David M., Rice, William G., Schmitt, Clemens, Lowe, Scott W., Johnstone, Ricky W., Pearson, Richard B., McArthur, Grant A., Hannan, Ross D.

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NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination von Ruscetti, Marcus, Leibold, Josef, Bott, Matthew J, Fennell, Myles, Kulick, Amanda, Salgado, Nelson R, Chen, Chi-Chao, Ho, Yu-Jui, Sanchez-Rivera, Francisco J, Feucht, Judith, Baslan, Timour, Tian, Sha, Chen, Hsuan-An, Romesser, Paul B, Poirier, John T, Rudin, Charles M, de Stanchina, Elisa, Manchado, Eusebio, Sherr, Charles J, Lowe, Scott W

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A combinatorial strategy for treating KRAS-mutant lung cancer von Manchado, Eusebio, Weissmueller, Susann, Morris, John P., Chen, Chi-Chao, Wullenkord, Ramona, Lujambio, Amaia, de Stanchina, Elisa, Poirier, John T., Gainor, Justin F., Corcoran, Ryan B., Engelman, Jeffrey A., Rudin, Charles M., Rosen, Neal, Lowe, Scott W.

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Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay von Fellmann, Christof, Zuber, Johannes, McJunkin, Katherine, Chang, Kenneth, Malone, Colin D., Dickins, Ross A., Xu, Qikai, Hengartner, Michael O., Elledge, Stephen J., Hannon, Gregory J., Lowe, Scott W.

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Senescence of Activated Stellate Cells Limits Liver Fibrosis von Krizhanovsky, Valery, Yon, Monica, Dickins, Ross A., Hearn, Stephen, Simon, Janelle, Miething, Cornelius, Yee, Herman, Zender, Lars, Lowe, Scott W.

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Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors von Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Schneider, William M., Luna, Joseph M., Soto-Feliciano, Yadira M., Ashbrook, Alison W., Le Pen, Jérémie, Leal, Andrew A., Ricardo-Lax, Inna, Michailidis, Eleftherios, Hao, Yuan, Stenzel, Ansgar F., Peace, Avery, Zuber, Johannes, Allis, C. David, Lowe, Scott W., MacDonald, Margaret R., Poirier, John T., Rice, Charles M.

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Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function von Sakamaki, Jun-ichi, Wilkinson, Simon, Hahn, Marcel, Tasdemir, Nilgun, O’Prey, Jim, Clark, William, Hedley, Ann, Nixon, Colin, Long, Jaclyn S., New, Maria, Van Acker, Tim, Tooze, Sharon A., Lowe, Scott W., Dikic, Ivan, Ryan, Kevin M.

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Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer von O'Rourke, Kevin P, Loizou, Evangelia, Livshits, Geulah, Schatoff, Emma M, Baslan, Timour, Manchado, Eusebio, Simon, Janelle, Romesser, Paul B, Leach, Benjamin, Han, Teng, Pauli, Chantal, Beltran, Himisha, Rubin, Mark A, Dow, Lukas E, Lowe, Scott W

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Life in the Fast Lane: Mammalian Disease Models in the Genomics Era von Dow, Lukas E., Lowe, Scott W.

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Dissecting eIF4E action in tumorigenesis von Wendel, Hans-Guido, Silva, Ricardo L A, Malina, Abba, Mills, John R, Zhu, Hong, Ueda, Takeshi, Watanabe-Fukunaga, Rie, Fukunaga, Rikiro, Teruya-Feldstein, Julie, Pelletier, Jerry, Lowe, Scott W

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MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia von Chen, Chong, Liu, Yu, Rappaport, Amy R., Kitzing, Thomas, Schultz, Nikolaus, Zhao, Zhen, Shroff, Aditya S., Dickins, Ross A., Vakoc, Christopher R., Bradner, James E., Stock, Wendy, LeBeau, Michelle M., Shannon, Kevin M., Kogan, Scott, Zuber, Johannes, Lowe, Scott W.

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Imaging of Liver Tumors Using Surface-Enhanced Raman Scattering Nanoparticles von Andreou, Chrysafis, Neuschmelting, Volker, Tschaharganeh, Darjus-Felix, Huang, Chun-Hao, Oseledchyk, Anton, Iacono, Pasquale, Karabeber, Hazem, Colen, Rivka R, Mannelli, Lorenzo, Lowe, Scott W, Kircher, Moritz F

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Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia von Glaser, Stefan P, Lee, Erinna F, Trounson, Evelyn, Bouillet, Philippe, Wei, Andrew, Fairlie, W Douglas, Izon, David J, Zuber, Johannes, Rappaport, Amy R, Herold, Marco J, Alexander, Warren S, Lowe, Scott W, Robb, Lorraine, Strasser, Andreas

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Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer von Paffenholz, Stella V, Salvagno, Camilla, Ho, Yu-Jui, Limjoco, Matthew, Baslan, Timour, Tian, Sha, Kulick, Amanda, de Stanchina, Elisa, Wilkinson, John E, Barriga, Francisco M, Zamarin, Dmitriy, Cubillos-Ruiz, Juan R, Leibold, Josef, Lowe, Scott W

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A New Development in Senescence von Banito, Ana, Lowe, Scott W.

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