Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362 von Lowe, Martin A., Cardenas, Alvaro, Valentin, Jean-Pierre, Zhu, Zhaoning, Abendroth, Jan, Castro, Jose L., Class, Reiner, Delaunois, Annie, Fleurance, Renaud, Gerets, Helga, Gryshkova, Vitalina, King, Lloyd, Lorimer, Donald D., MacCoss, Malcolm, Rowley, Julian H., Rosseels, Marie-Luce, Royer, Leandro, Taylor, Richard D., Wong, Melanie, Zaccheo, Oliver, Chavan, Vishal P., Ghule, Gokul A., Tapkir, Bapusaheb K., Burrows, Jeremy N., Duffey, Maëlle, Rottmann, Matthias, Wittlin, Sergio, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Striepen, Josefine, Fairhurst, Kate J., Yeo, Tomas, Fidock, David A., Cowman, Alan F., Favuzza, Paola, Crespo-Fernandez, Benigno, Gamo, Francisco Javier, Goldberg, Daniel E., Soldati-Favre, Dominique, Laleu, Benoît, de Haro, Teresa

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Assessing the interplay between off-target promiscuity, cytotoxicity, and tolerability in rodents to improve the safety profile of novel anti-malarial plasmepsin X inhibitors von Gerets, Helga H J, Delaunois, Annie, Cardenas, Alvaro, Class, Reiner, Fleurance, Renaud, de Haro, Teresa, Laleu, Benoît, Lowe, Martin A, Rosseels, Marie-Luce, Valentin, Jean-Pierre

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Deconvoluting and derisking QRS complex widening to improve cardiac safety profile of novel plasmepsin X antimalarials von Delaunois, Annie, Cardenas, Alvaro, de Haro, Teresa, Gerets, Helga H J, Gryshkova, Vitalina, Hebeisen, Simon, Korlowski, Chloé, Laleu, Benoit, Lowe, Martin A, Valentin, Jean-Pierre

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Palladium-Mediated Annulation of Vinyl Aziridines with Michael Acceptors: Stereocontrolled Synthesis of Substituted Pyrrolidines and Its Application in a Formal Synthesis of (−)-α-... von Lowe, Martin A., Ostovar, Mehrnoosh, Ferrini, Serena, Chen, C. Chun, Lawrence, Paul G., Fontana, Francesco, Calabrese, Andrew A., Aggarwal, Varinder K.

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Design of Novel Series of Antimalarial PMX Inhibitors with Increased Half-Life via Molecular Property Optimization von Sakata, Komei, Lowe, Martin A, Xuan, Mengyang, Bruffaerts, Jeffrey, Stasi, Luigi P, Lallemand, Bénédicte, Cardenas, Alvaro, Taylor, Richard D, Vidler, Lewis R, King, Lloyd, Valentin, Jean-Pierre, Laleu, Benoît, de Haro, Teresa

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Fused thiophene derivatives as MEK inhibitors von Laing, Victoria E., Brookings, Daniel C., Carbery, Rachel J., Simorte, Jose Gascon, Hutchings, Martin C., Langham, Barry J., Lowe, Martin A., Allen, Rodger A., Fetterman, Joanne R., Turner, James, Meier, Christoph, Kennedy, Jeff, Merriman, Mark

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Palladium-Mediated Annulation of Vinyl Aziridines with Michael Acceptors: Stereocontrolled Synthesis of Substituted Pyrrolidines and Its Application in a Formal Synthesis of (-)-[a... von Lowe, Martin A, Ostovar, Mehrnoosh, Ferrini, Serena, Chen, C Chun, Lawrence, Paul G, Fontana, Francesco, Calabrese, Andrew A, Aggarwal, Varinder K

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Palladium-Mediated Annulation of Vinyl Aziridines with Michael Acceptors: Stereocontrolled Synthesis of Substituted Pyrrolidines and Its Application in a Formal Synthesis of (-)-[a... von Lowe, Martin A, Ostovar, Mehrnoosh, Ferrini, Serena, Chen, C Chun, Lawrence, Paul G, Fontana, Francesco, Calabrese, Andrew A, Aggarwal, Varinder K

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Palladium-Mediated Annulation of Vinyl Aziridines with Michael Acceptors: Stereocontrolled Synthesis of Substituted Pyrrolidines and Its Application in a Formal Synthesis of (−)-α-... von Lowe, Martin A., Ostovar, Mehrnoosh, Ferrini, Serena, Chen, C. Chun, Lawrence, Paul G., Fontana, Francesco, Calabrese, Andrew A., Aggarwal, Varinder K.

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tRNAscan-SE: Searching for tRNA Genes in Genomic Sequences von Chan, Patricia P., Lowe, Todd M.

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Structural organization of the Golgi apparatus von Lowe, Martin

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GOLPH3 keeps the Golgi residents at home von Lowe, Martin

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GOLPH3 keeps the Golgi residents at home von Lowe, Martin

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The Physiological Functions of the Golgin Vesicle Tethering Proteins von Lowe, Martin

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Parametric Functional Maps of Visual Inputs to the Tectum von Nikolaou, Nikolas, Lowe, Andrew S., Walker, Alison S., Abbas, Fatima, Hunter, Paul R., Thompson, Ian D., Meyer, Martin P.

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Associations between stroke mortality and weekend working by stroke specialist physicians and registered nurses: prospective multicentre cohort study von Bray, Benjamin D, Ayis, Salma, Campbell, James, Cloud, Geoffrey C, James, Martin, Hoffman, Alex, Tyrrell, Pippa J, Wolfe, Charles D A, Rudd, Anthony G

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Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Glycemia and Childhood Glucose Metabolism von Scholtens, Denise M, Kuang, Alan, Lowe, Lynn P, Hamilton, Jill, Lawrence, Jean M, Lebenthal, Yael, Brickman, Wendy J, Clayton, Peter, Ma, Ronald C, McCance, David, Tam, Wing Hung, Catalano, Patrick M, Linder, Barbara, Dyer, Alan R, Lowe, Jr, William L, Metzger, Boyd E

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Using large clinical data sets to infer pathogenicity for rare copy number variants in autism cohorts von Moreno-De-Luca, D, Sanders, S J, Willsey, A J, Mulle, J G, Lowe, J K, Geschwind, D H, State, M W, Martin, C L, Ledbetter, D H

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Priority Actions to Improve Provenance Decision-Making von BREED, MARTIN F., HARRISON, PETER A., BISCHOFF, ARMIN, DURRUTY, PAULA, GELLIE, NICK J. C., GONZALES, EMILY K., HAVENS, KAYRI, KARMANN, MARION, KILKENNY, FRANCIS F., KRAUSS, SIEGFRIED L., LOWE, ANDREW J., MARQUES, PEDRO, NEVILL, PAUL G., VITT, PATI L., BUCHAROVA, ANNA

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Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Gestational Diabetes Mellitus and Childhood Glucose Metabolism von Lowe, Jr, William L, Scholtens, Denise M, Kuang, Alan, Linder, Barbara, Lawrence, Jean M, Lebenthal, Yael, McCance, David, Hamilton, Jill, Nodzenski, Michael, Talbot, Octavious, Brickman, Wendy J, Clayton, Peter, Ma, Ronald C, Tam, Wing Hung, Dyer, Alan R, Catalano, Patrick M, Lowe, Lynn P, Metzger, Boyd E

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