Introducing Biochemistry to Bedside von Lowe, Derek B

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Drug discovery: Combichem all over again von Lowe, Derek B

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Combichem all over again von Lowe, Derek B.

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Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3‑Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of M... von Come, Jon H, Collier, Philip N, Henderson, James A, Pierce, Albert C, Davies, Robert J, Le Tiran, Arnaud, O’Dowd, Hardwin, Bandarage, Upul K, Cao, Jingrong, Deininger, David, Grey, Ron, Krueger, Elaine B, Lowe, Derek B, Liang, Jianglin, Liao, Yusheng, Messersmith, David, Nanthakumar, Suganthi, Sizensky, Emmanuelle, Wang, Jian, Xu, Jinwang, Chin, Elaine Y, Damagnez, Veronique, Doran, John D, Dworakowski, Wojciech, Griffith, James P, Jacobs, Marc D, Khare-Pandit, Suvarna, Mahajan, Sudipta, Moody, Cameron S, Aronov, Alex M

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In vitro SAR of (5-(2 H)-isoxazolonyl) ureas, potent inhibitors of hormone-sensitive lipase von Lowe, Derek B., Magnuson, Steven, Qi, Ning, Campbell, Ann-Marie, Cook, James, Hong, Zhenqiu, Wang, Ming, Rodriguez, Mareli, Achebe, Furahi, Kluender, Harold, Wong, Wai C., Bullock, William H., Salhanick, Arthur I., Witman-Jones, Terri, Bowling, Mary E., Keiper, Christine, Clairmont, Kevin B.

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Nowhere To Go But Up: The Return of Medicinal Chemistry von Lowe, Derek B

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Quinazolinone Derivatives as Orally Available Ghrelin Receptor Antagonists for the Treatment of Diabetes and Obesity von Rudolph, Joachim, Esler, William P, O'Connor, Stephen, Coish, Philip D. G, Wickens, Philip L, Brands, Michael, Bierer, Donald E, Bloomquist, Brian T, Bondar, Georgiy, Chen, Libing, Chuang, Chih-Yuan, Claus, Thomas H, Fathi, Zahra, Fu, Wenlang, Khire, Uday R, Kristie, James A, Liu, Xiao-Gao, Lowe, Derek B, McClure, Andrea C, Michels, Martin, Ortiz, Astrid A, Ramsden, Philip D, Schoenleber, Robert W, Shelekhin, Tatiana E, Vakalopoulos, Alexandros, Tang, Weifeng, Wang, Lei, Yi, Lin, Gardell, Stephen J, Livingston, James N, Sweet, Laurel J, Bullock, William H

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4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17β-hydroxysteroid dehydrogenase. Part 3. Identification of lead candidate von Wood, Jill, Bagi, Cedo M., Akuche, Christiana, Bacchiocchi, Antonietta, Baryza, Jeremy, Blue, Marie-Luise, Brennan, Catherine, Campbell, Ann-Marie, Choi, Soongyu, Cook, James H., Conrad, Patricia, Dixon, Brian R., Ehrlich, Paul P., Gane, Todd, Gunn, David, Joe, Ted, Johnson, Jeffrey S., Jordan, Jerold, Kramss, Richard, Liu, Peiying, Levy, Joan, Lowe, Derek B., McAlexander, Ian, Natero, Reina, Redman, Anikó M., Scott, William J., Town, Christopher, Wang, Ming, Wang, Yamin, Zhang, Zhonghua

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SCH 57790, a selective muscarinic M2 receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals von CAREY, Galen J, BILLARD, William, TEDESCO, Richard P, WATKINS, Robert W, COFFIN, Vicki L, BINCH, Herbert III, COHEN-WILLIAMS, Mary, CROSBY, Gordon, GRZELAK, Michael, GUZIK, Henry, KOZLOWSKI, Joseph A, LOWE, Derek B, POND, Annamarie J

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Drug Seekers von Lowe, Derek B.

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Substituted indanylacetic acids as PPAR-α–γ activators von Lowe, Derek B., Bifulco, Neil, Bullock, William H., Claus, Thomas, Coish, Philip, Dai, Miao, Dela Cruz, Fernando E., Dickson, David, Fan, Dongping, Hoover-Litty, Helana, Li, Tindy, Ma, Xin, Mannelly, Gretchen, Monahan, Mary-Katherine, Muegge, Ingo, O’Connor, Stephen, Rodriguez, Mareli, Shelekhin, Tatiana, Stolle, Andreas, Sweet, Laurel, Wang, Ming, Wang, Yamin, Zhang, Chengzhi, Zhang, Hai-Jun, Zhang, Mingbao, Zhao, Kake, Zhao, Qian, Zhu, Jian, Zhu, Lei, Tsutsumi, Manami

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Diphenyl sulfoxides as selective antagonists of the muscarinic M2 receptor von KOZLOWSKI, Joseph A, LOWE, Derek B, BINCH, Herbert III, LACHOWICZ, Jean E, GUZIK, Henry S, GUOWEI ZHOU, RUPERTO, Vilma B, DUFFY, Ruth A, MCQUADE, Robert, CROSBY, Gordon JR, TAYLOR, Lisa A, BILLARD, William

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SCH 57790, a selective muscarinic M 2 receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals von Carey, Galen J., Billard, William, Binch, Herbert, Cohen-Williams, Mary, Crosby, Gordon, Grzelak, Michael, Guzik, Henry, Kozlowski, Joseph A., Lowe, Derek B., Pond, Annamarie J., Tedesco, Richard P., Watkins, Robert W., Coffin, Vicki L.

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4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17beta-hydroxysteroid dehydrogenase. Part 3. Identification of lead candidate von Wood, Jill, Bagi, Cedo M, Akuche, Christiana, Bacchiocchi, Antonietta, Baryza, Jeremy, Blue, Marie-Luise, Brennan, Catherine, Campbell, Ann-Marie, Choi, Soongyu, Cook, James H, Conrad, Patricia, Dixon, Brian R, Ehrlich, Paul P, Gane, Todd, Gunn, David, Joe, Ted, Johnson, Jeffrey S, Jordan, Jerold, Kramss, Richard, Liu, Peiying, Levy, Joan, Lowe, Derek B, McAlexander, Ian, Natero, Reina, Redman, Anikó M, Scott, William J, Town, Christopher, Wang, Ming, Wang, Yamin, Zhang, Zhonghua

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Diphenyl sulfoxides as selective antagonists of the muscarinic M 2 receptor von Kozlowski, Joseph A, Lowe, Derek B, Guzik, Henry S, Zhou, Guowei, Ruperto, Vilma B, Duffy, Ruth A, McQuade, Robert, Crosby, Gordon, Taylor, Lisa A, Billard, William, Binch, Herbert, Lachowicz, Jean E

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In vitro SAR of (5-(2H)-Isoxazolonyl) Ureas, Potent Inhibitors of Hormone-Sensitive Lipase von Lowe, Derek B., ., et al

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Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation von ZHANG CHENGZHI, COISH PHILIP D. G, LOWE DEREK B, BULLOCK WILLIAM H, WANG YAMIN, LIVINGSTON JAMES N, MA XIN, ZHU LEI, ZHANG MINGBAO, STOLLE ANDREAS, WICKENS PHILIP L, ZHANG HAI-JUN, MUGGE INGO A, TSUTSUMI MANAMI, WANG MING

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Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation von ZHANG CHENGZHI, COISH PHILIP D. G, LOWE DEREK B, BULLOCK WILLIAM H, WANG YAMIN, LIVINGSTON JAMES N, MA XIN, ZHU LEI, ZHANG MINGBAO, STOLLE ANDREAS, WICKENS PHILIP L, ZHANG HAI-JUN, MUGGE INGO A, TSUTSUMI MANAMI, WANG MING

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MUSCARINIC ANTAGONIST von DUGAR SUNDEEP, CHANG WEI K, LOWE DEREK B, KOZLOWSKI JOSEPH A

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Dopamine receptor binding properties of some 2,3,4,5-tetrahydro-1H-3-benzazepine-7-ols with non-aromatic substituents in the 5-position von Chang, Wei K., Peters, Marjorie, Fevig, Vicki P., Kozlowski, Joseph A., Zhou, Gouwei, Lowe, Derek B., Guzik, Henry, McQuade, Robert D., Duffy, Ruth, Coffin, Vicki L., Berger, Joel G.

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