Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study von Choueiri, Toni K, Shyr, Yu, Grivas, Petros, Thompson, Michael A, Bilen, Mehmet A, Bouganim, Nathaniel, Doroshow, Deborah B, Egan, Pamela C, Elkrief, Arielle, Farmakiotis, Dimitrios, Glover, Michael J, Griffiths, Elizabeth A, Gulati, Anthony P, Gupta, Shilpa, Hsu, Emily, Lemmon, Christopher A, Lewis, Colleen, Masters, Tyler, Mesa, Ruben A, Morgans, Alicia K, Reynolds, Kerry, Rosen, Lane R, Schmidt, Andrew, Shaya, Justin A, Wulff-Burchfield, Elizabeth, Xie, Zhuoer, Yu, Peter P, Zubiri, Leyre, Warner, Jeremy L, Acoba, Jared D., Agarwal, Neeraj, Ahmad, Syed, Ajmera, Archana, Angevine, Anne H., Azad, Nilo, Barnholtz-Sloan, Jill, Barrow, Briana, Boland, Genevieve, Bonnen, Mark, Bouchard, Gabrielle, Busser, Fiona, Casulo, Carla, Curran, Catherine, Deeken, John, Demetri, George D., DiLullo, Sandy, Elias, Rawad, Feldman, Lawrence E., Friese, Christopher R., Fu, Paul, Gillaspie, Erin A., Giordano, Antonio, Glace, (Mary) Grace, Gurley, Michael, Halmos, Balazs, Johnson, Douglas B., Koshkin, Vadim S., Leighton, John C., Li, Xuanyi, LoRusso, Patricia, Low, Clarke A., Mansoor, Abdul-Hai, Handy Marshall, Catherine, Matar, Sara, McNair, Christopher, Mehnert, Janice M., Menon, Harry, Nagle, Sarah, Nakayama, John M., Nelson, Heather H., Nemecek, Eneida R., Nuzzo, Pier Vitale, Oberstein, Paul E., Owenby, Susie, Pasquinelli, Mary M., Revankar, Sanjay G., Rho, Young Soo, Rhodes, Terence D., Rice, Robert L., Riess, Jonathan, Routy, Bertrand, Rovito, Marc A., Saif, M. Wasif, Sanyal, Amit, Serrano, Oscar, Shah, Mansi, Shaw, Grace, Shergill, Ardaman, Stauffer, Karen, Stratton, Jamie, Stratton, Catherine, Subbiah, Vivek, Tannir, Nizar M., Van Allen, Eli, Verma, Amit K., Vikas, Praveen, Weiss, Matthias, Wise-Draper, Trisha, Wood, William A., Zacks, Rosemary

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European recommendations integrating genetic testing into multidisciplinary management of sudden cardiac death von Fellmann, Florence, van El, Carla G, Charron, Philippe, Michaud, Katarzyna, Howard, Heidi C, Boers, Sarah N, Clarke, Angus J, Duguet, Anne-Marie, Forzano, Francesca, Kauferstein, Silke, Kayserili, Hülya, Lucassen, Anneke, Mendes, Álvaro, Patch, Christine, Radojkovic, Dragica, Rial-Sebbag, Emmanuelle, Sheppard, Mary N, Tassé, Anne-Marie, Temel, Sehime G, Sajantila, Antti, Basso, Cristina, Wilde, Arthur A M, Cornel, Martina C

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Risk factor profiles and clinical outcomes for children and adults with pneumococcal infections in Singapore: A need to expand vaccination policy? von Martinez-Vega, Rosario, Jauneikaite, Elita, Thoon, Koh Cheng, Chua, Hui Ying, Huishi Chua, Amanda, Khong, Wei Xin, Tan, Ban Hock, Low Guek Hong, Jenny, Venkatachalam, Indumathi, Anantharajah Tambyah, Paul, Hibberd, Martin L, Clarke, Stuart C, Ng, Oon Tek

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Optimal inverter VAR control in distribution systems with high PV penetration von Farivar, M., Neal, R., Clarke, C., Low, S.

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P311 Bone disease in CF: what’s the current situation? von Moore, F., Low, M.S.A., Clarke, E.

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Measuring the burden and mortality of hospitalisation in Parkinson's disease: A cross-sectional analysis of the English Hospital Episodes Statistics database 2009–2013 von Low, Vincent, Ben-Shlomo, Yoav, Coward, Elena, Fletcher, Suzanne, Walker, Richard, Clarke, Carl E

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A novel framework for evaluating in situ breeding management strategies in endangered populations von Robledo‐Ruiz, Diana A., Pavlova, Alexandra, Clarke, Rohan H., Magrath, Michael J. L., Quin, Bruce, Harrisson, Katherine A., Gan, Han Ming, Low, Gabriel W., Sunnucks, Paul

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PUF60 variants cause a syndrome of ID, short stature, microcephaly, coloboma, craniofacial, cardiac, renal and spinal features von Low, Karen J, Ansari, Morad, Abou Jamra, Rami, Clarke, Angus, El Chehadeh, Salima, FitzPatrick, David R, Greenslade, Mark, Henderson, Alex, Hurst, Jane, Keller, Kory, Kuentz, Paul, Prescott, Trine, Roessler, Franziska, Selmer, Kaja K, Schneider, Michael C, Stewart, Fiona, Tatton-Brown, Katrina, Thevenon, Julien, Vigeland, Magnus D, Vogt, Julie, Willems, Marjolaine, Zonana, Jonathan, Study, D D D, Smithson, Sarah F

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Lipid Nanoparticle-Mediated Gene Editing of Human Primary T Cells and Off-Target Analysis of the CRISPR-Cas9 Indels von Geczy, Reka, Thommandru, Bernice, Swaminathan, Meenakshi, Zhao, Rita, Tan, Krystal, Low, Kevin, Balgi, Aruna, Park, Stella, Watt, Ethan, Thada, Vaughn, Rettig, Garrett, Zhang, Angela, Turk, Rolf, Clarke, Samuel

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Promoting Independence Through Quality Dementia Care at Home (PITCH): An Australian Stepped‐Wedge Cluster Randomised Controlled Trial Evaluating a Dementia Training Program for Hom... von Dow, Briony, Savvas, Steven, Dang, Christa, Batchelor, Frances, Doyle, Colleen, Cooper, Claudia, Livingston, Gill, Wise, Erica, Tan, Esther, Panayiotou, Anita, Malta, Sue, Clarke, Philip, Burton, Jason, Low, Lee‐Fay, Loi, Samantha M., Fairhall, Anne, Polacsek, Meg, Lyketsos, Constantine, Scherer, Samuel, Ames, David, Engel, Lidia, Goh, Anita M. Y.

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Opioid-induced hyperalgesia: a review of epidemiology, mechanisms and management von LOW, Yinghui, CLARKE, Collin F, HUH, Billy K

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Promoting Independence Through quality dementia Care at Home (PITCH): a research protocol for a stepped-wedge cluster-randomised controlled trial von Savvas, Steven, Goh, Anita M Y, Batchelor, Frances, Doyle, Colleen, Wise, Erica, Tan, Esther, Panayiotou, Anita, Malta, Sue, Winbolt, Margaret, Clarke, Phillip, Burton, Jason, Low, Lee-Fay, Loi, Samantha M, Fairhall, Anne, Polacsek, Meg, Stiles, Jay, Muliadi, Fenny, Chau, Nadia, Scherer, Samuel, Ames, David, Sousa, Tanara Vieira, Dow, Briony

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OPTIMIZATION OF MULTIPLEX CRISPR-CAS9 EDITING OF HUMAN PRIMARY T CELLS USING LIPID NANOPARTICLES (LNPS) AND SUBSEQUENT OFF-TARGET EVALUATION von Swaminathan, M., Thommandru, B.C., Geczy, R., Zhao, R., Tan, K., Low, K., Balgi, A., Park, S., Watt, E., Thada, V., Rettig, G., Zhang, A., Turk, R., Clarke, S.

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Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer’s Disease von Martone, Robert L., Zhou, Hua, Atchison, Kevin, Comery, Thomas, Xu, Jane Z., Huang, Xinyi, Gong, Xioahai, Jin, Mei, Kreft, Anthony, Harrison, Boyd, Mayer, Scott C., Aschmies, Suzan, Gonzales, Cathleen, Zaleska, Margaret M., Riddell, David R., Wagner, Erik, Lu, Peimin, Sun, Shaiu-Ching, Sonnenberg-Reines, June, Oganesian, Aram, Adkins, Karissa, Leach, Michael W., Clarke, David W., Huryn, Donna, Abou-Gharbia, Magid, Magolda, Ronald, Bard, Jonathan, Frick, Glen, Raje, Sangeeta, Forlow, S. Bradley, Balliet, Carrie, Burczynski, Michael E., Reinhart, Peter H., Wan, Hong I., Pangalos, Menelas N., Jacobsen, J. Steven

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Abstract 898: Evaluation of cellular senescence through fluorescence characterization von Clarke, Scott T., Jackson, Taryn, Kelley, Amanda, Low, Quentin, Huang, Timothy, Hu, Yi-Zhen, Calderon, Veronica, Wang, Rong, O'Grady, Michael

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Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice von YUQING HUO, LEI ZHAO, SRINIVASAN, Suseela, HEDRICK, Catherine C, PRATICO, Domenico, WITZTUM, Joseph L, NADLER, Jerry L, FUNK, Colin D, LEY, Klaus, HYMAN, Matthew Craig, SHASHKIN, Pavel, HARRY, Brian L, BURCIN, Tracy, FORLOW, S. Bradley, STARK, Matthew A, SMITH, David F, CLARKE, Sean

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Elucidating the survival and response of carbapenem resistant Klebsiella pneumoniae after exposure to imipenem at sub-lethal concentrations von Low, Ye Mun, Chong, Chun Wie, Yap, Ivan Kok Seng, Chai, Lay Ching, Clarke, Stuart C., Ponnampalavanar, Sasheela, Abdul Jabar, Kartini, Md Yusof, Mohd Yasim, Teh, Cindy Shuan Ju

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The spectrum of heart defects in the TRAF7 -related multiple congenital anomalies-intellectual disability syndrome von Pisan, Elise, De Luca, Chiara, Brancati, Francesco, Sanchez Russo, Rossana, Li, Dong, Bhoj, Elizabeth, Wenger, Tara, Marwaha, Ashish, Johnson, Nicole, Beneteau, Claire, Brischoux-Boucher, Elise, Houge, Gunnar, Paulsen, Julie, Hammer, Trine Bjørg, Ek, Jakob, Schweitzer, Daniela, Russell, Bianca E, Dutra-Clarke, Marina, Nelson, Stanley, Douine, Emilie D, Corona, Rosario I, Dudding, Tracy, Thomson, Hannah, Low, Karen, Belnap, Newell, Iascone, Maria, Priolo, Manuela, Carli, Diana, Mussa, Alessandro, Bijlsma, Emilia K, Kopp, Nathan, Jais, Jean-Philippe, Amiel, Jeanne, Gordon, Christopher T

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Feasibility, Reliability, and Validity of an Electronic Frailty Index Based on Comprehensive Geriatric Assessment (Efi-CGA) in Primary Care: A Prospective Cohort Study of 100 Patie... von Song, Xiaowei, Park, Grace, Clarke, Barry, Low, Hilary, Penwarden, Jodie, Harding, Kaitlin, Fay, Sheeri, Robinson, Belinda, Rockwood, Kenneth

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Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): pooled trial results, systematic review, and meta-analys... von Blake, P, Swart, Ann Marie, Orton, J, Kitchener, H, Whelan, T, Lukka, H, Eisenhauer, E, Bacon, M, Tu, D, Parmar, M K B, Amos, C, Murray, C, Qian, W

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