B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers von Fukazawa, Yoshinori, Lum, Richard, Okoye, Afam A, Park, Haesun, Matsuda, Kenta, Bae, Jin Young, Hagen, Shoko I, Shoemaker, Rebecca, Deleage, Claire, Lucero, Carissa, Morcock, David, Swanson, Tonya, Legasse, Alfred W, Axthelm, Michael K, Hesselgesser, Joseph, Geleziunas, Romas, Hirsch, Vanessa M, Edlefsen, Paul T, Piatak, Michael, Estes, Jacob D, Lifson, Jeffrey D, Picker, Louis J

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New Paradigms for HIV AIDS Vaccine Development von Picker, Louis J, Hansen, Scott G, Lifson, Jeffrey D

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Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound von Okoye, Afam A., Hansen, Scott G., Vaidya, Mukta, Fukazawa, Yoshinori, Park, Haesun, Duell, Derick M., Lum, Richard, Hughes, Colette M., Ventura, Abigail B., Ainslie, Emily, Ford, Julia C., Morrow, David, Gilbride, Roxanne M., Legasse, Alfred W., Hesselgesser, Joseph, Geleziunas, Romas, Li, Yuan, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J., Borate, Bhavesh R., Edlefsen, Paul T., Axthelm, Michael K., Picker, Louis J., Lifson, Jeffrey D.

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection von Douek, Daniel C, Brenchley, Jason M, Price, David A, Schacker, Timothy W, Asher, Tedi E, Silvestri, Guido, Rao, Srinivas, Kazzaz, Zachary, Bornstein, Ethan, Lambotte, Olivier, Altmann, Daniel, Blazar, Bruce R, Rodriguez, Benigno, Teixeira-Johnson, Leia, Landay, Alan, Martin, Jeffrey N, Hecht, Frederick M, Picker, Louis J, Lederman, Michael M, Deeks, Steven G

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Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir von Keele, Brandon F, Okoye, Afam A, Fennessey, Christine M, Varco-Merth, Benjamin, Immonen, Taina T, Kose, Emek, Conchas, Andrew, Pinkevych, Mykola, Lipkey, Leslie, Newman, Laura, Macairan, Agatha, Bosche, Marjorie, Bosche, William J, Berkemeier, Brian, Fast, Randy, Hull, Mike, Oswald, Kelli, Shoemaker, Rebecca, Silipino, Lorna, Gorelick, Robert J, Duell, Derick, Marenco, Alejandra, Brantley, William, Smedley, Jeremy, Axthelm, Michael, Davenport, Miles P, Lifson, Jeffrey D, Picker, Louis J

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Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding von Walters, Lucy C., Harlos, Karl, Brackenridge, Simon, Rozbesky, Daniel, Barrett, Jordan R., Jain, Vitul, Walter, Thomas S., O’Callaghan, Chris A., Borrow, Persephone, Toebes, Mireille, Hansen, Scott G., Sacha, Jonah B, Abdulhaqq, Shaheed, Greene, Justin M., Früh, Klaus, Marshall, Emily, Picker, Louis J., Jones, E. Yvonne, McMichael, Andrew J., Gillespie, Geraldine M.

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Marked skewing of entire T-cell memory compartment occurs only in a minority of CMV-infected individuals and is unrelated to the degree of memory subset skewing among CMV-specific... von Fuhrmann, Stephan, Reus, Bernhard, Frey, Oliver, Pera, Alejandra, Picker, Louis J., Kern, Florian

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The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription von Okoye, Afam A, Fromentin, Rémi, Takata, Hiroshi, Brehm, Jessica H, Fukazawa, Yoshinori, Randall, Bryan, Pardons, Marion, Tai, Vincent, Tang, Jun, Smedley, Jeremy, Axthelm, Michael, Lifson, Jeffrey D, Picker, Louis J, Favre, David, Trautmann, Lydie, Chomont, Nicolas

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Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge von Hansen, Scott G, Womack, Jennie, Scholz, Isabel, Renner, Andrea, Edgel, Kimberly A, Xu, Guangwu, Ford, Julia C, Grey, Mikayla, St Laurent, Brandyce, Turner, John M, Planer, Shannon, Legasse, Al W, Richie, Thomas L, Aguiar, Joao C, Axthelm, Michael K, Villasante, Eileen D, Weiss, Walter, Edlefsen, Paul T, Picker, Louis J, Früh, Klaus

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Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence von Varco-Merth, Benjamin, Chaunzwa, Morgan, Duell, Derick M, Marenco, Alejandra, Goodwin, William, Dannay, Rachel, Nekorchuk, Michael, Shao, Danica, Busman-Sahay, Kathleen, Fennessey, Christine M, Silipino, Lorna, Hull, Michael, Bosche, William J, Fast, Randy, Oswald, Kelli, Shoemaker, Rebecca, Bochart, Rachele, MacAllister, Rhonda, Labriola, Caralyn S, Smedley, Jeremy V, Axthelm, Michael K, Davenport, Miles P, Edlefsen, Paul T, Estes, Jacob D, Keele, Brandon F, Lifson, Jeffrey D, Lewin, Sharon R, Picker, Louis J, Okoye, Afam A

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Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy von Varco-Merth, Benjamin D, Brantley, William, Marenco, Alejandra, Duell, Derick D, Fachko, Devin N, Richardson, Brian, Busman-Sahay, Kathleen, Shao, Danica, Flores, Walter, Engelman, Kathleen, Fukazawa, Yoshinori, Wong, Scott W, Skalsky, Rebecca L, Smedley, Jeremy, Axthelm, Michael K, Lifson, Jeffrey D, Estes, Jacob D, Edlefsen, Paul T, Picker, Louis J, Cameron, Cheryl Ma, Henrich, Timothy J, Okoye, Afam A

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Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion von Ranasinghe, Srinika, Lamothe, Pedro A., Soghoian, Damien Z., Kazer, Samuel W., Cole, Michael B., Shalek, Alex K., Yosef, Nir, Jones, R. Brad, Donaghey, Faith, Nwonu, Chioma, Jani, Priya, Clayton, Gina M., Crawford, Frances, White, Janice, Montoya, Alana, Power, Karen, Allen, Todd M., Streeck, Hendrik, Kaufmann, Daniel E., Picker, Louis J., Kappler, John W., Walker, Bruce D.

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CD4+ T-cell depletion in HIV infection: mechanisms of immunological failure von Okoye, Afam A., Picker, Louis J.

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Functional genomic analysis of the 68-1 RhCMV- Mycobacteria tuberculosis vaccine reveals an IL-15 response signature that is conserved with vector attenuation von Sung, Cheng-Jung, Whitmore, Leanne S, Smith, Elise, Chang, Jean, Tisoncik-Go, Jennifer, Barber-Axthelm, Aaron, Selseth, Andrea, Feltham, Shana, Ojha, Sohita, Hansen, Scott G, Picker, Louis J, Gale, Jr, Michael

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Cytomegalovirus vaccine vector-induced effector memory CD4 + T cells protect cynomolgus macaques from lethal aerosolized heterologous avian influenza challenge von Malouli, Daniel, Tiwary, Meenakshi, Gilbride, Roxanne M., Morrow, David W., Hughes, Colette M., Selseth, Andrea, Penney, Toni, Castanha, Priscila, Wallace, Megan, Yeung, Yulia, Midgett, Morgan, Williams, Connor, Reed, Jason, Yu, Yun, Gao, Lina, Yun, Gabin, Treaster, Luke, Laughlin, Amanda, Lundy, Jeneveve, Tisoncik-Go, Jennifer, Whitmore, Leanne S., Aye, Pyone P., Schiro, Faith, Dufour, Jason P., Papen, Courtney R., Taher, Husam, Picker, Louis J., Früh, Klaus, Gale, Michael, Maness, Nicholas J., Hansen, Scott G., Barratt-Boyes, Simon, Reed, Douglas S., Sacha, Jonah B.

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Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice von Crawford, Lindsey B., Tempel, Rebecca, Streblow, Daniel N., Kreklywich, Craig, Smith, Patricia, Picker, Louis J., Nelson, Jay A., Caposio, Patrizia

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Viral escape mutations do not account for non-protection from SIVmac239 challenge in RhCMV/SIV vaccinated rhesus macaques von Bimber, Benjamin N, Sunshine, Justine, McElfresh, G W, Reed, Jason S, Pathak, Reese, Bateman, Katherine B, Hughes, Colette M, Gilbride, Roxanne M, Ford, Julia C, Morrow, David, Lifson, Jeffrey D, Sacha, Jonah B, Hansen, Scott G, Picker, Louis J

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Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus von Sturgill, Elizabeth R, Malouli, Daniel, Hansen, Scott G, Burwitz, Benjamin J, Seo, Seongkyung, Schneider, Christine L, Womack, Jennie L, Verweij, Marieke C, Ventura, Abigail B, Bhusari, Amruta, Jeffries, Krystal M, Legasse, Alfred W, Axthelm, Michael K, Hudson, Amy W, Sacha, Jonah B, Picker, Louis J, Früh, Klaus

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Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques von Burwitz, Benjamin J, Malouli, Daniel, Bimber, Benjamin N, Reed, Jason S, Ventura, Abigail B, Hancock, Meaghan H, Uebelhoer, Luke S, Bhusari, Amruta, Hammond, Katherine B, Espinosa Trethewy, Renee G, Klug, Alex, Legasse, Alfred W, Axthelm, Michael K, Nelson, Jay A, Park, Byung S, Streblow, Daniel N, Hansen, Scott G, Picker, Louis J, Früh, Klaus, Sacha, Jonah B

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Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaques von Brochu, Hayden N, Smith, Elise, Jeong, Sangmi, Carlson, Michelle, Hansen, Scott G, Tisoncik-Go, Jennifer, Law, Lynn, Picker, Louis J, Gale, Jr, Michael, Peng, Xinxia

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