MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease von Banerjee, S, Oneda, B, Yap, L M, Jewell, D P, Matters, G L, Fitzpatrick, L R, Seibold, F, Sterchi, E E, Ahmad, T, Lottaz, D, Bond, J S

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Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus von Schütte, André, Ermund, Anna, Becker-Pauly, Christoph, Johansson, Malin E. V., Rodriguez-Pineiro, Ana M., Bäckhed, Fredrik, Müller, Stefan, Lottaz, Daniel, Bond, Judith S., Hansson, Gunnar C.

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WS12.3 Detachment of mucus requires a specific proteolytic cleavage in the MUC2 mucin explaining why the cystic fibrosis mucus is attached to the epithelium von Schütte, A, Ermund, A, Becker-Pauly, C, Johansson, M.E.V, Rodríguez-Pineiro, A.M, Bäckhed, F, Müller, S, Lottaz, D, Bond, J.S, Hansson, G.C

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Differential regulation of metzincins in experimental chronic renal allograft rejection: Potential markers and novel therapeutic targets von Berthier, C.C., Lods, N., Joosten, S.A., van Kooten, C., Leppert, D., Lindberg, R.L.P., Kappeler, A., Raulf, F., Sterchi, E.E., Lottaz, D., Marti, H.-P.

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Inhibition of ATP-Binding Cassette Transporter Downregulates Interleukin-1β-Mediated Autocrine Activation of Human Dermal Fibroblasts von Lottaz, Daniel, Beleznay, Zsuzsanna, Bickel, Matthias

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Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors von Kruse, Markus-N, Becker, Christoph, Lottaz, Daniel, Köhler, Danny, Yiallouros, Irene, Krell, Hans-Willi, Sterchi, Erwin E, Stöcker, Walter

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Activation of human meprin-alpha in a cell culture model of colorectal cancer is triggered by the plasminogen-activating system von Rösmann, Sandra, Hahn, Dagmar, Lottaz, Daniel, Kruse, Markus-N, Stöcker, Walter, Sterchi, Erwin E

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P666 Type 1 pili and long polar fimbriae are essential for induction of host-microbiota mutualism by adherent-invasive Escherichia coli, even in the presence of competing intestina... von Vazeille, E., Balmer, M.L., Chassaing, B., Stefan Müller, S., Thomas Schaffer, T., Slack, E., Pfister, S., Geuking, M.B., Lottaz, D., Macpherson, A.J., Hapfelmeier, S., McCoy, K.D., Darfeuille-Michaud, A.

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Maturation of human lactase-phlorizin hydrolase Proteolytic cleavage of precursor occurs after passage through the Golgi complex von Lottaz, D., Oberholzer, T., Bähler, P., Semenza, G., Sterchi, E.E.

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Nonpolarized secretion of human meprin α in colorectal cancer generates an increased proteolytic potential in the stroma von LOTTAZ, D, MAURER, C. A, HAHN, D, BÜCHLER, M. W, STERCHI, E. E

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OP12 Multiple functional variants at the 3p21 locus contribute to ulcerative colitis: Results from a European consortium von Cleynen, I., Artieda, M., Verspaget, H., Szczypiorska, M., Seibold, F., Lakatos, P., Ahmad, T., Weersma, R., Mahachie, J., Arijs, I., Müller, S., Parnell, K., Tordai, A., Hommes, D.W., Van Steen, K., Wijmenga, C., Rutgeerts, P., Lottaz, D., Vermeire, S.

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P242 - Prioritization of mucosal protease/protease inhibitor candidate genes in inflammatory bowel disease through a systematic review analysis approach von Cleynen, I., Mendes, C.T., Bekkering, G.E., Kellen, E., Jüni, P., Rutgeerts, P., Vermeire, S., Lottaz, D.

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MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease von Banerjee, S, Oneda, Beatrice, Yap, L M, Jewell, D P, Matters, G L, Fitzpatrick, L R, Seibold, F, Sterchi, E E, Ahmad, T, Lottaz, D, Bond, J S

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OP19 Genetic and functional evidence for a role for CYLD in Crohn's disease: Results from a European consortium von Cleynen, I., Vazeille, E., Artieda, M., Szczypiorska, M., Bringer, M.-A., Verspaget, H., Lakatos, P., Seibold, F., Parnell, K., Weersma, R., Mahachie, J., Morgan-Walsh, R., Staelens, D., Arijs, I., Müller, S., Tordai, A., Hommes, D.W., Ahmad, T., Wijmenga, C., Pender, S., Rutgeerts, P., Lottaz, D., Van Steen, K., Vermeire, S., Darfeuille-Michaud, A.

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Inhibition of ATP-binding cassette transporter downregulates interleukin-1beta-mediated autocrine activation of human dermal fibroblasts von Lottaz, D, Beleznay, Z, Bickel, M

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Soluble interleukin-1 receptor — reverse signaling in innate immunoregulation von Spörri, Bernhard, Bickel, Matthias, Dobbelaere, Dirk, Machado, Joel, Lottaz, Daniel

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Polymorphisms in the MEP1A Gene: A Role in IBD? von Yap, L. M., Lottaz, D., Ahmad, T., Zhang, L., Van Heel, D., McGovern, D., Negoro, K., Sterchi, E., Sanderson, I., Welsh, K., Jewell, D. P.

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Polymorphisms in the MEP1A gene are not associated with susceptibility to coeliac disease von Yap, L.M, Lottaz, D, Ahmad, T, Zhang, L, Van Heel, D, McGovern, D, Negoro, K, Sterchi, E, Sanderson, I, Welsh, K, Jewell, D.P

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Secretion of human meprin from intestinal epithelial cells depends on differential expression of the α and β subunits von Lottaz, Daniel, Hahn, Dagmar, Müller, Stefan, Müller, Christoph, Sterchi, Erwin E.

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Meprin mRNA in rat intestine during normal and glucocorticoid-induced maturation: divergent patterns of expression of α and β subunits von Henning, Susan J., Oesterreicher, Thomas J., Osterholm, Doreen E., Lottaz, Daniel, Hahn, Dagmar, Sterchi, Erwin E.

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