A mechanistic overview of translation initiation in eukaryotes von Aitken, Colin Echeverría, Lorsch, Jon R

Volltext

Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex von Llácer, Jose L., Hussain, Tanweer, Marler, Laura, Aitken, Colin Echeverría, Thakur, Anil, Lorsch, Jon R., Hinnebusch, Alan G., Ramakrishnan, V.

Volltext

Perspective: Sustaining the big-data ecosystem von Bourne, Philip E., Lorsch, Jon R., Green, Eric D.

Volltext

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex von Hussain, Tanweer, Llácer, Jose L., Fernández, Israel S., Munoz, Antonio, Martin-Marcos, Pilar, Savva, Christos G., Lorsch, Jon R., Hinnebusch, Alan G., Ramakrishnan, V.

Volltext

Applied research won't flourish without basic science von Lorsch, Jon R, Tabak, Lawrence A, Bertagnolli, Monica M

Volltext

Yeast Ded1 promotes 48S translation pre-initiation complex assembly in an mRNA-specific and eIF4F-dependent manner von Gupta, Neha, Lorsch, Jon R, Hinnebusch, Alan G

Volltext

THE MOLECULAR MECHANICS OF EUKARYOTIC TRANSLATION von Kapp, Lee D, Lorsch, Jon R

Volltext

Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo von Gulay, Suna, Gupta, Neha, Lorsch, Jon R, Hinnebusch, Alan G

Volltext

eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide von Zhou, Fujun, Zhang, Hongen, Kulkarni, Shardul D, Lorsch, Jon R, Hinnebusch, Alan G

Volltext

Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity von Yourik, Paul, Aitken, Colin Echeverría, Zhou, Fujun, Gupta, Neha, Hinnebusch, Alan G, Lorsch, Jon R

Volltext

Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition von Llácer, Jose Luis, Hussain, Tanweer, Saini, Adesh K, Nanda, Jagpreet Singh, Kaur, Sukhvir, Gordiyenko, Yuliya, Kumar, Rakesh, Hinnebusch, Alan G, Lorsch, Jon R, Ramakrishnan, V

Volltext

Molecular Architecture of a Eukaryotic Translational Initiation Complex von Fernández, Israel S., Bai, Xiao-Chen, Hussain, Tanweer, Kelley, Ann C., Lorsch, Jon R., Ramakrishnan, V., Scheres, Sjors H. W.

Volltext

Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system von Zhou, Fujun, Bocetti, Julie M, Hou, Meizhen, Qin, Daoming, Hinnebusch, Alan G, Lorsch, Jon R

Volltext

Coordinated Movements of Eukaryotic Translation Initiation Factors eIF1, eIF1A, and eIF5 Trigger Phosphate Release from eIF2 in Response to Start Codon Recognition by the Ribosomal... von Nanda, Jagpreet S., Saini, Adesh K., Muñoz, Antonio M., Hinnebusch, Alan G., Lorsch, Jon R.

Volltext

Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae von Kulkarni, Shardul D, Zhou, Fujun, Sen, Neelam Dabas, Zhang, Hongen, Hinnebusch, Alan G, Lorsch, Jon R

Volltext

The Eukaryotic Translation Initiation Factors eIF1 and eIF1A Induce an Open Conformation of the 40S Ribosome von Passmore, Lori A., Schmeing, T. Martin, Maag, David, Applefield, Drew J., Acker, Michael G., Algire, Mikkel A., Lorsch, Jon R., Ramakrishnan, V.

Volltext

Fixing problems with cell lines von Lorsch, Jon R, Collins, Francis S, Lippincott-Schwartz, Jennifer

Volltext

Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex von Aitken, Colin Echeverría, Beznosková, Petra, Vlčkova, Vladislava, Chiu, Wen-Ling, Zhou, Fujun, Valášek, Leoš Shivaya, Hinnebusch, Alan G, Lorsch, Jon R

Volltext

The mechanism of eukaryotic translation initiation: new insights and challenges von Hinnebusch, Alan G, Lorsch, Jon R

Volltext

eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast von Martin-Marcos, Pilar, Zhou, Fujun, Karunasiri, Charm, Zhang, Fan, Dong, Jinsheng, Nanda, Jagpreet, Kulkarni, Shardul D, Sen, Neelam Dabas, Tamame, Mercedes, Zeschnigk, Michael, Lorsch, Jon R, Hinnebusch, Alan G

Volltext