Evolution of glacial lakes from the Northern Patagonia Icefield and terrestrial water storage in a sea-level rise context von Loriaux, Thomas, Casassa, Gino

Volltext

Spatio-Temporal Distribution of Supra-Glacial Ponds and Ice Cliffs on Verde Glacier, Chile von Loriaux, Thomas, Ruiz, Lucas

Volltext

Assessing glacier melt contribution to streamflow at Universidad Glacier, central Andes of Chile von Bravo, Claudio, Loriaux, Thomas, Rivera, Andrés, Brock, Ben W

Volltext

50 MHz helicopter-borne radar data for determination of glacier thermal regime in the central Chilean Andes von Gacitúa, Guisella, Uribe, José A., Wilson, Ryan, Loriaux, Thomas, Hernández, Jorge, Rivera, Andrés

Volltext

A new glacier inventory for the Southern Patagonia Icefield and areal changes 1986–2000 von Casassa, Gino, Rodríguez, José Luis, Loriaux, Thomas

Volltext

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance von O'Hare, Thomas, Shakespeare, William C., Zhu, Xiaotian, Eide, Christopher A., Rivera, Victor M., Wang, Frank, Adrian, Lauren T., Zhou, Tianjun, Huang, Wei-Sheng, Xu, Qihong, Metcalf, Chester A., Tyner, Jeffrey W., Loriaux, Marc M., Corbin, Amie S., Wardwell, Scott, Ning, Yaoyu, Keats, Jeffrey A., Wang, Yihan, Sundaramoorthi, Raji, Thomas, Mathew, Zhou, Dong, Snodgrass, Joseph, Commodore, Lois, Sawyer, Tomi K., Dalgarno, David C., Deininger, Michael W.N., Druker, Brian J., Clackson, Tim

Volltext

CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms von Tyner, Jeffrey W., Bumm, Thomas G., Deininger, Jutta, Wood, Lisa, Aichberger, Karl J., Loriaux, Marc M., Druker, Brian J., Burns, Christopher J., Fantino, Emmanuelle, Deininger, Michael W.

Volltext

Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening von TYNER, Jeffrey W, YANG, Wayne F, KOVACSOVICS, Tibor, GOTLIB, Jason R, OH, Stephen T, DEININGER, Michael W, MICHEL ZWAAN, Christian, DEN BOER, Monique L, VAN DEN HEUVEL-EIBRINK, Marry M, O'HARE, Thomas, DRUKER, Brian J, LORIAUX, Marc M, BANKHEAD, Armand, GUANG FAN, FLETCHER, Luke B, BRYANT, Jade, GLOVER, Jason M, CHANG, Bill H, SPURGEON, Stephen E, FLEMING, William H

Volltext

Activating alleles of JAK3 in acute megakaryoblastic leukemia von Walters, Denise K., Mercher, Thomas, Gu, Ting-Lei, O'Hare, Thomas, Tyner, Jeffrey W., Loriaux, Marc, Goss, Valerie L., Lee, Kimberly A., Eide, Christopher A., Wong, Matthew J., Stoffregen, Eric P., McGreevey, Laura, Nardone, Julie, Moore, Sandra A., Crispino, John, Boggon, Titus J., Heinrich, Michael C., Deininger, Michael W., Polakiewicz, Roberto D., Gilliland, D. Gary, Druker, Brian J.

Volltext

Absence of SKP2 expression attenuates BCR-ABL–induced myeloproliferative disease von Agarwal, Anupriya, Bumm, Thomas G.P., Corbin, Amie S., O'Hare, Thomas, Loriaux, Marc, VanDyke, Jonathan, Willis, Stephanie G., Deininger, Jutta, Nakayama, Keiichi I., Druker, Brian J., Deininger, Michael W.

Volltext

RNAi screen for rapid therapeutic target identification in leukemia patients von Tyner, Jeffrey W, Deininger, Michael W, Loriaux, Marc M, Chang, Bill H, Gotlib, Jason R, Willis, Stephanie G, Erickson, Heidi, Kovacsovics, Tibor, O'Hare, Thomas, Heinrich, Michael C, Druker, Brian J

Volltext

Double autophagy stimulation using chemotherapy and mTOR inhibition combined with hydroxychloroquine for autophagy modulation in patients with relapsed or refractory multiple myelo... von Scott, Emma C, Maziarz, Richard T, Spurgeon, Stephen E, Medvedova, Eva, Gajewski, James, Reasor-Heard, Shara, Park, Byung, Kratz, Anne, Thomas, George V, Loriaux, Marc, Cascio, Michael, Podolak, Jennifer, Gordon, Miranda, Botelho, Jennifer, Stadtmauer, Edward, Amaravadi, Ravi, Vogl, Dan T

Volltext

The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia von Levine, Ross L., Loriaux, Marc, Huntly, Brian J.P., Loh, Mignon L., Beran, Miroslav, Stoffregen, Eric, Berger, Roland, Clark, Jennifer J., Willis, Stephanie G., Nguyen, Kim T., Flores, Nikki J., Estey, Elihu, Gattermann, Norbert, Armstrong, Scott, Look, A. Thomas, Griffin, James D., Bernard, Olivier A., Heinrich, Michael C., Gilliland, D. Gary, Druker, Brian, Deininger, Michael W.N.

Volltext

BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein von Agarwal, Anupriya, Mackenzie, Ryan J., Besson, Arnaud, Jeng, Sophia, Carey, Alyssa, LaTocha, Dorian H., Fleischman, Angela G., Duquesnes, Nicolas, Eide, Christopher A., Vasudevan, Kavin B., Loriaux, Marc M., Firpo, Eduardo, Cortes, Jorge E., McWeeney, Shannon, O’Hare, Thomas, Roberts, James M., Druker, Brian J., Deininger, Michael W.

Volltext

Thoracic Nerve Root Entrapment by Intrathecal Catheter Coiling: Case Report and Review of the Literature von Han, Jing L, Loriaux, Daniel B, Tybout, Caroline, Kinon, Merritt D, Rahimpour, Shervin, Runyon, Scott L, Hopkins, Thomas J, Boortz-Marx, Richard L, Lad, Shivanand P

Volltext

RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia von Tyner, Jeffrey W., Walters, Denise K., Willis, Stephanie G., Luttropp, Mary, Oost, Jason, Loriaux, Marc, Erickson, Heidi, Corbin, Amie S., O'Hare, Thomas, Heinrich, Michael C., Deininger, Michael W., Druker, Brian J.

Volltext

A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice von Johnson, Kara J, Griswold, Ian J, O'Hare, Thomas, Corbin, Amie S, Loriaux, Marc, Deininger, Michael W, Druker, Brian J

Volltext

Activating Mutations Observed in De Novo Acute Myeloid Leukemia Are Also Present in a Subset of Philadelphia Chromosome (Ph)-Positive Leukemia Patients with BCR-ABL1-Independent Re... von Eide, Christopher A., Savage, Samantha L., Agarwal, Anupriya, Bottomly, Daniel, Wilmot, Beth, McWeeney, Shannon K., Kurtz, Stephen E., O’Hare, Thomas, Deininger, Michael W., Loriaux, Marc M., Tognon, Cristina E., Tyner, Jeffrey W., Druker, Brian J.

Volltext

Characterization of the Genomic Landscape of BCR-ABL1 Kinase-Independent Mechanisms of Resistance to ABL1 Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia von Eide, Christopher A., Bottomly, Daniel, Savage, Samantha L., White, Libbey, Wilmot, Beth, Reister Schultz, Anna M., Uchida, Kimberly A., Agarwal, Anupriya, Traer, Elie, Beppu, Lan, Sala-Torra, Olga, Radich, Jerald P., Eickelberg, Garrett, Press, Richard D., Loriaux, Marc M., Tantravahi, Srinivas K., Pomicter, Anthony D., Zabriskie, Matthew S., Deininger, Michael W., O'Hare, Thomas, Tyner, Jeffrey W., McWeeney, Shannon K., Tognon, Cristina E., Druker, Brian J.

Volltext

TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms von Fleischman, Angela G., Aichberger, Karl J., Luty, Samuel B., Bumm, Thomas G., Petersen, Curtis L., Doratotaj, Shirin, Vasudevan, Kavin B., LaTocha, Dorian H., Yang, Fei, Press, Richard D., Loriaux, Marc M., Pahl, Heike L., Silver, Richard T., Agarwal, Anupriya, O'Hare, Thomas, Druker, Brian J., Bagby, Grover C., Deininger, Michael W.

Volltext