High content screening: seeing is believing von Zanella, Fabian, Lorens, James B, Link, Wolfgang

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Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer von Ludwig, Kathleen F, Du, Wenting, Sorrelle, Noah B, Wnuk-Lipinska, Katarzyna, Topalovski, Mary, Toombs, Jason E, Cruz, Victoria H, Yabuuchi, Shinichi, Rajeshkumar, N V, Maitra, Anirban, Lorens, James B, Brekken, Rolf A

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Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival von Gjerdrum, Christine, Tiron, Crina, Høiby, Torill, Stefansson, Ingunn, Haugen, Hallvard, Sandal, Tone, Collett, Karin, Li, Shan, McCormack, Emmet, Gjertsen, Bjørn Tore, Micklem, David R, Akslen, Lars A, Glackin, Carlotta, Lorens, James B

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Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis von Kirane, Amanda, Ludwig, Kathleen F, Sorrelle, Noah, Haaland, Gry, Sandal, Tone, Ranaweera, Renate, Toombs, Jason E, Wang, Miao, Dineen, Sean P, Micklem, David, Dellinger, Michael T, Lorens, James B, Brekken, Rolf A

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Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome von Parlati, Francesco, Lee, Susan J., Aujay, Monette, Suzuki, Erika, Levitsky, Konstantin, Lorens, James B., Micklem, David R., Ruurs, Paulina, Sylvain, Catherine, Lu, Yan, Shenk, Kevin D., Bennett, Mark K.

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Vimentin-ERK Signaling Uncouples Slug Gene Regulatory Function von Virtakoivu, Reetta, Mai, Anja, Mattila, Elina, De Franceschi, Nicola, Imanishi, Susumu Y, Corthals, Garry, Kaukonen, Riina, Saari, Markku, Cheng, Fang, Torvaldson, Elin, Kosma, Veli-Matti, Mannermaa, Arto, Muharram, Ghaffar, Gilles, Christine, Eriksson, John, Soini, Ylermi, Lorens, James B, Ivaska, Johanna

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In vivo turnover and biodistribution of soluble AXL: implications for biomarker development von Tenstad, Olav, Christakou, Eleni, Hodneland Nilsson, Linn, Gausdal, Gro, Micklem, David, Kursula, Petri, Lorens, James B., Reed, Rolf K.

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C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer von Liu, Xiao-Zheng, Rulina, Anastasiia, Choi, Man Hung, Pedersen, Line, Lepland, Johanna, Takle, Sina T., Madeleine, Noelly, Peters, Stacey D’mello, Wogsland, Cara Ellen, Grøndal, Sturla Magnus, Lorens, James B., Goodarzi, Hani, Lønning, Per E., Knappskog, Stian, Molven, Anders, Halberg, Nils

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Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition von Engelsen, Agnete S T, Lotsberg, Maria L, Abou Khouzam, Raefa, Thiery, Jean-Paul, Lorens, James B, Chouaib, Salem, Terry, Stéphane

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Mural cell associated VEGF is required for organotypic vessel formation von Evensen, Lasse, Micklem, David R, Blois, Anna, Berge, Sissel Vik, Aarsaether, Niels, Littlewood-Evans, Amanda, Wood, Jeanette, Lorens, James B

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Cellular context-mediated Akt dynamics regulates MAP kinase signaling thresholds during angiogenesis von Hellesøy, Monica, Lorens, James B

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Inhibiting the GAS6/AXL axis suppresses tumor progression by blocking the interaction between cancer-associated fibroblasts and cancer cells in gastric carcinoma von Bae, Cheong A., Ham, In-Hye, Oh, Hye Jeong, Lee, Dagyeong, Woo, Jongsu, Son, Sang-Yong, Yoon, Jung Hwan, Lorens, James B., Brekken, Rolf A., Kim, Tae-Min, Han, Sang-Uk, Park, Won Sang, Hur, Hoon

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Targeting AXL cellular networks in kidney fibrosis von Grøndal, Sturla M, Blø, Magnus, Nilsson, Linn I H, Rayford, Austin J, Jackson, Akil, Gausdal, Gro, Lorens, James B

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Age-Related Dysfunction in Mechanotransduction Impairs Differentiation of Human Mammary Epithelial Progenitors von Pelissier, Fanny A., Garbe, James C., Ananthanarayanan, Badriprasad, Miyano, Masaru, Lin, ChunHan, Jokela, Tiina, Kumar, Sanjay, Stampfer, Martha R., Lorens, James B., LaBarge, Mark A.

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AXL expression reflects tumor-immune cell dynamics impacting outcome in non-small cell lung cancer patients treated with immune checkpoint inhibitor monotherapy von Rayford, Austin, Gärtner, Fabian, Ramnefjell, Maria P, Lorens, James B, Micklem, David R, Aanerud, Marianne, Engelsen, Agnete S T

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Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity von Terry, Stéphane, Buart, Stéphanie, Tan, Tuan Zea, Gros, Gwendoline, Noman, Muhammad Zaeem, Lorens, James B., Mami-Chouaib, Fathia, Thiery, Jean Paul, Chouaib, Salem

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High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia von Pelissier Vatter, Fanny A., Schapiro, Denis, Chang, Hang, Borowsky, Alexander D., Lee, Jonathan K., Parvin, Bahram, Stampfer, Martha R., LaBarge, Mark A., Bodenmiller, Bernd, Lorens, James B.

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Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties von Nikolaisen, Julie, Nilsson, Linn I H, Pettersen, Ina K N, Willems, Peter H G M, Lorens, James B, Koopman, Werner J H, Tronstad, Karl J

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Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dime... von Lotsberg, Maria L, Røsland, Gro V, Rayford, Austin J, Dyrstad, Sissel E, Ekanger, Camilla T, Lu, Ning, Frantz, Kirstine, Stuhr, Linda E B, Ditzel, Henrik J, Thiery, Jean Paul, Akslen, Lars A, Lorens, James B, Engelsen, Agnete S T

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p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model von Olsen, Jan Roger, Oyan, Anne Margrete, Rostad, Kari, Hellem, Margrete R, Liu, Jie, Li, Lisha, Micklem, David R, Haugen, Hallvard, Lorens, James B, Rotter, Varda, Ke, Xi-Song, Lin, Biaoyang, Kalland, Karl-Henning

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