Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model von Lordén, Gema, Wozniak, Jacob M., Doré, Kim, Dozier, Lara E., Cates-Gatto, Chelsea, Patrick, Gentry N., Gonzalez, David J., Roberts, Amanda J., Tanzi, Rudolph E., Newton, Alexandra C.

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Protein kinase Cα gain-of-function variant in Alzheimer’s disease displays enhanced catalysis by a mechanism that evades down-regulation von Callender, Julia A., Yang, Yimin, Lordén, Gema, Stephenson, Natalie L., Jones, Alexander C., Brognard, John, Newton, Alexandra C.

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mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif von Baffi, Timothy R, Lordén, Gema, Wozniak, Jacob M, Feichtner, Andreas, Yeung, Wayland, Kornev, Alexandr P, King, Charles C, Del Rio, Jason C, Limaye, Ameya J, Bogomolovas, Julius, Gould, Christine M, Chen, Ju, Kennedy, Eileen J, Kannan, Natarajan, Gonzalez, David J, Stefan, Eduard, Taylor, Susan S, Newton, Alexandra C

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Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity von Peña, Lucía, Meana, Clara, Astudillo, Alma M., Lordén, Gema, Valdearcos, Martín, Sato, Hiroyasu, Murakami, Makoto, Balsinde, Jesús, Balboa, María A.

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The phosphatidic acid phosphatase lipin-1 facilitates inflammation-driven colon carcinogenesis von Meana, Clara, García-Rostán, Ginesa, Peña, Lucía, Lordén, Gema, Cubero, África, Orduña, Antonio, Győrffy, Balázs, Balsinde, Jesús, Balboa, María A

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Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation von Lordén, Gema, Sanjuán-García, Itziar, de Pablo, Nagore, Meana, Clara, Alvarez-Miguel, Inés, Pérez-García, M Teresa, Pelegrín, Pablo, Balsinde, Jesús, Balboa, María A

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Protein kinase C fusion proteins are paradoxically loss of function in cancer von Van, An-Angela N., Kunkel, Maya T., Baffi, Timothy R., Lordén, Gema, Antal, Corina E., Banerjee, Sourav, Newton, Alexandra C.

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The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch von Kawashima, Agnieszka T., Wong, Cassandra, Lordén, Gema, King, Charles C., Lara-Gonzalez, Pablo, Desai, Arshad, Gingras, Anne-Claude, Newton, Alexandra C.

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PHLPP1 counter-regulates STAT1-mediated inflammatory signaling von Cohen Katsenelson, Ksenya, Stender, Joshua D, Kawashima, Agnieszka T, Lordén, Gema, Uchiyama, Satoshi, Nizet, Victor, Glass, Christopher K, Newton, Alexandra C

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Lipin-1 integrates lipid synthesis with proinflammatory responses during TLR activation in macrophages von Meana, Clara, Peña, Lucía, Lordén, Gema, Esquinas, Esperanza, Guijas, Carlos, Valdearcos, Martín, Balsinde, Jesús, Balboa, María A

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Novel PKC signaling in Alzheimer’s Disease von Gauron, M. C., Lorden, Gema, Prokopenko, Dmitry, Tanzi, Rudolph, Newton, Alexandra

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Amplified Protein Kinase C Signaling in Alzheimer's Disease von Lorden, Gema, Wosniak, Jacob M., Dozier, Lara E., Patrick, Gentry N., Gonzalez, David J., Roberts, Amanda J., Newton, Alexandra C.

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The Protein Phosphatase PHLPP1 Suppresses Insulin Signaling and Inflammation in Mouse Model von Lorden, Gema, Skovsø, Søs, Riopel, Matthew, Cohen‐Katsenelson, Ksenya, Johnson, James D., Newton, Alexandra C.

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Protein kinase Ca gain-of-function variant in Alzheimer’s disease displays enhanced catalysis by a mechanism that evades down-regulation von Callender, Julia A, Yang, Yimin, Lordén, Gema, Stephenson, Natalie L, Jones, Alexander C, Brognard, John, Newton, Alexandra C

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Lipin‐1 Links Lipid Signaling with Inflammation von Balboa, María, Meana, Clara, Lordén, Gema, Balsinde, Jesús

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Conventional protein kinase C in the brain: repurposing cancer drugs for neurodegenerative treatment? von Lordén, Gema, Newton, Alexandra C

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mTORC2 Controls PKC and Akt by Phosphorylating a Conserved TOR-Interaction Motif von Baffi, Timothy R., Lordén, Gema, Wozniak, Jacob M., Feichtner, Andreas, Yeung, Wayland, Kornev, Alexandr P., King, Charles C., Del Rio, Jason C., Limaye, Ameya J., Bogomolovas, Julius, Gould, Christine M., Chen, Ju, Kennedy, Eileen J., Kannan, Natarajan, Gonzalez, David J., Stefan, Eduard, Taylor, Susan S., Newton, Alexandra C.

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