Design, Synthesis, and Pharmacological Evaluation of N‑Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase‑4 Inh... von Kümmerle, Arthur E, Schmitt, Martine, Cardozo, Suzana V. S, Lugnier, Claire, Villa, Pascal, Lopes, Alexandra B, Romeiro, Nelilma C, Justiniano, Hélène, Martins, Marco A, Fraga, Carlos A. M, Bourguignon, Jean-Jacques, Barreiro, Eliezer J

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Structure-based design and biological profile of ( E)- N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of IκB kinase-β von Avila, Carolina M., Lopes, Alexandra B., Gonçalves, Arlan S., da Silva, Leandro L., Romeiro, Nelilma C., Miranda, Ana Luisa P., Sant’Anna, Carlos M.R., Barreiro, Eliezer J., Fraga, Carlos A.M.

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D149. Efficacy of Topical Tranexamic Acid in Gender-Affirming Mastectomy von Falade, Israel, Lopes, Alexandra, Song, Siyou, Kim, Esther A.

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Structure-based design and biological profile of (E)-N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of IKB kinase-β von AVILA, Carolina M, LOPES, Alexandra B, GONCALVES, Arlan S, DA SILVA, Leandro L, ROMEIRO, Nelilma C, MIRANDA, Ana Luisa P, SANT'ANNA, Carlos M. R, BARREIRO, Eliezer J, FRAGA, Carlos A. M

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In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and impairs their motor function von Cordova, Fabiano M, Aguiar, Jr, Aderbal S, Peres, Tanara V, Lopes, Mark W, Gonçalves, Filipe M, Remor, Aline P, Lopes, Samantha C, Pilati, Célso, Latini, Alexandra S, Prediger, Rui D S, Erikson, Keith M, Aschner, Michael, Leal, Rodrigo B

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Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1 von Lopes, Alexandra M, Aston, Kenneth I, Thompson, Emma, Carvalho, Filipa, Gonçalves, João, Huang, Ni, Matthiesen, Rune, Noordam, Michiel J, Quintela, Inés, Ramu, Avinash, Seabra, Catarina, Wilfert, Amy B, Dai, Juncheng, Downie, Jonathan M, Fernandes, Susana, Guo, Xuejiang, Sha, Jiahao, Amorim, António, Barros, Alberto, Carracedo, Angel, Hu, Zhibin, Hurles, Matthew E, Moskovtsev, Sergey, Ober, Carole, Paduch, Darius A, Schiffman, Joshua D, Schlegel, Peter N, Sousa, Mário, Carrell, Douglas T, Conrad, Donald F

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Bi-allelic Recessive Loss-of-Function Variants in FANCM Cause Non-obstructive Azoospermia von Kasak, Laura, Punab, Margus, Nagirnaja, Liina, Grigorova, Marina, Minajeva, Ave, Lopes, Alexandra M., Punab, Anna Maria, Aston, Kenneth I., Carvalho, Filipa, Laasik, Eve, Smith, Lee B., Conrad, Donald F., Laan, Maris

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Variant PNLDC1, Defective piRNA Processing, and Azoospermia von Nagirnaja, Liina, Mørup, Nina, Nielsen, John E, Stakaitis, Rytis, Golubickaite, Ieva, Oud, Manon S, Winge, Sofia B, Carvalho, Filipa, Aston, Kenneth I, Khani, Francesca, van der Heijden, Godfried W, Marques, C. Joana, Skakkebaek, Niels E, Rajpert–De Meyts, Ewa, Schlegel, Peter N, Jørgensen, Niels, Veltman, Joris A, Lopes, Alexandra M, Conrad, Donald F, Almstrup, Kristian

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Spindle cell oncocytoma of the pituitary gland von Giantini Larsen, Alexandra M, Cote, David J, Zaidi, Hasan A, Bi, Wenya Linda, Schmitt, Paul J, Iorgulescu, J Bryan, Miller, Michael B, Smith, Timothy R, Lopes, M Beatriz, Jane, John A, Laws, Edward R

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Local iron homeostasis in the breast ductal carcinoma microenvironment von Marques, Oriana, Porto, Graça, Rêma, Alexandra, Faria, Fátima, Cruz Paula, Arnaud, Gomez-Lazaro, Maria, Silva, Paula, Martins da Silva, Berta, Lopes, Carlos

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Electrokinetic remediation of contaminants of emergent concern in clay soil: Effect of operating parameters von Guedes, Paula, Lopes, Vanda, Couto, Nazaré, Mateus, Eduardo P., Pereira, Cristina Silva, Ribeiro, Alexandra B.

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A Non-Toxic Binuclear Vanadium(IV) Complex as Insulin Adjuvant Improves the Glycemic Control in Streptozotocin-Induced Diabetic Rats von Lopes, Mateus S, Baptistella, Gabriel B, Nunes, Giovana G, Ferreira, Matheus V, Cunha, Joice Maria, Oliveira, Kauê Marcel de, Acco, Alexandra, Lopes, Maria Luiza C, Couto Alves, Alexessander, Valdameri, Glaucio, Moure, Vivian R, Picheth, Geraldo, Manica, Graciele C M, Rego, Fabiane G M

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Left Atrial Strain Quantification by Intraoperative Transesophageal Echocardiography: Validation With Transthoracic Echocardiography von Rong, Lisa Q., Menon, Ajay, Lopes, Alexandra J., Agoglia, Hannah, Tak, Katherine, Devereux, Richard B., Rahouma, Mohamed, Gaudino, Mario, Weinsaft, Jonathan W., Kim, Jiwon

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Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure von Teerlink, John R, Diaz, Rafael, Felker, G. Michael, McMurray, John J.V, Metra, Marco, Solomon, Scott D, Adams, Kirkwood F, Anand, Inder, Arias-Mendoza, Alexandra, Biering-Sørensen, Tor, Böhm, Michael, Bonderman, Diana, Cleland, John G.F, Corbalan, Ramon, Crespo-Leiro, Maria G, Dahlström, Ulf, Echeverria, Luis E, Fang, James C, Filippatos, Gerasimos, Fonseca, Cândida, Goncalvesova, Eva, Goudev, Assen R, Howlett, Jonathan G, Lanfear, David E, Li, Jing, Lund, Mayanna, Macdonald, Peter, Mareev, Viacheslav, Momomura, Shin-ichi, O’Meara, Eileen, Parkhomenko, Alexander, Ponikowski, Piotr, Ramires, Felix J.A, Serpytis, Pranas, Sliwa, Karen, Spinar, Jindrich, Suter, Thomas M, Tomcsanyi, Janos, Vandekerckhove, Hans, Vinereanu, Dragos, Voors, Adriaan A, Yilmaz, Mehmet B, Zannad, Faiez, Sharpsten, Lucie, Legg, Jason C, Varin, Claire, Honarpour, Narimon, Abbasi, Siddique A, Malik, Fady I, Kurtz, Christopher E

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Safety and efficacy of avalglucosidase alfa versus alglucosidase alfa in patients with late-onset Pompe disease (COMET): a phase 3, randomised, multicentre trial von Diaz-Manera, Jordi, Kishnani, Priya S, Ladha, Shafeeq, Mozaffar, Tahseen, Straub, Volker, Berger, Kenneth I, Chien, Yin-Hsiu, Day, John W, Illarioshkin, Sergey, Roberts, Mark, Attarian, Shahram, Borges, Joao Lindolfo, Choi, Young Chul, Goker-Alpan, Ozlem, Kostera-Pruszczyk, Anna, Haack, Kristina An, Hug, Christopher, Huynh-Ba, Olivier, Johnson, Judith, Thibault, Nathan, Zhou, Tianyue, Dimachkie, Mazen M, Behin, Anthony, Boentert, Matthias, Carvalho, Gerson, Chahin, Nizar, Deegan, Patrick, Duval, Fanny, Genge, Angela, Gutmann, Ludwig, Henderson, Robert D, Hennermann, Julia B, Hiwot, Tarekegn, Hughes, Derralynn, Karaa, Amel, Komaki, Hirofumi, Longo, Nicola, Malinova, Vera, Maxit, Clarisa, Mengel, Eugen, Moggio, Maurizio Gualtiero, Mongini, Tiziana Enrica, Nascimento Osorio, Andres, Noury, Jean-Baptiste, Oliveira, Acary Souza Bulle, Pena, Loren, Remiche, Gauthier, Sciacco, Monica, Smith, Cheryl, Stulnig, Thomas, Taithe, Frederic, Tarnopolsky, Mark, Young, Peter, Alonso-Pérez, Jorge, Altemus, Patricia, Aubé-Nathier, Anne-Catherine, Avelar, Jennifer B, Billy, Jenny, Boschi, Silvia, Carrera Garcia, Laura, Chase, Lauren, Danjoux, Loïc, Davion, Jean-Baptiste, DeArmey, Stephanie, Gandolfo, Eve, Grosz, Zoltan, Guellec, Dewi, Guettsches, Anne-Katrin, Guglieri, Michela, Hatcher, Erin, Hufgard-Leitner, Miriam, Klyushnikov, Sergey A., Langton, Jacqui, Linková, Lenka, Mavroudakis, Nicolas, Mazurová, Stella, Mori, Madoka, Müller-Miny, Louisa, Natera-de Benito, Daniel, Neel, Robert, Niizawa, Gabriela A, Noll, Lauren, Pasnoor, Mamatha, Questienne, Claire, Ramos Lopes, Margarida, Riedl, Michaela, Salort-Campana, Emmanuelle, Sole, Guilhem, Solera, Luca, Souto Lopes, Suzara, Specht, Sabine, Statland, Jeffrey, Swenson, Andrea, Tan, Chong Yew, Tizon, Sónia, van der Beek, N A M E, van Kooten, Harmke A., Wencel, Marie, Wenninger, Stephan, Zagnoli, Fabien

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Progress and remaining challenges for cancer control in Latin America and the Caribbean von Strasser-Weippl, Kathrin, MD, Chavarri-Guerra, Yanin, MD, Villarreal-Garza, Cynthia, Prof, Bychkovsky, Brittany L, MD, Debiasi, Marcio, MD, Liedke, Pedro E R, MD, Soto-Perez-de-Celis, Enrique, Dizon, Don, MD, Cazap, Eduardo, MD, de Lima Lopes, Gilberto, MD, Touya, Diego, MD, Nunes, Joāo Soares, MD, Louis, Jessica St, BA, Vail, Caroline, BS, Bukowski, Alexandra, BS, Ramos-Elias, Pier, MD, Unger-Saldaña, Karla, PhD, Brandao, Denise Froes, MD, Ferreyra, Mayra E, MD, Luciani, Silvana, MHSc, Nogueira-Rodrigues, Angelica, MD, de Carvalho Calabrich, Aknar Freire, MD, Del Carmen, Marcela G, MD, Rauh-Hain, Jose Alejandro, MD, Schmeler, Kathleen, Prof, Sala, Raúl, MD, Goss, Paul E, Prof

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Relative Impact of Surgical Mitral Repair and MitraClip on Annular Remodeling—A Potential Mechanism for Therapeutic Response to Mitral Repair for Degenerative Mitral Regurgitation... von Rong, Lisa Q., Lopes, Alexandra J., Mitlak, Hannah W., Palumbo, Maria C., Mick, Stephanie, Kim, Jiwon, Levine, Robert A., Wong, S. Chiu, Reisman, Mark, Devereux, Richard B., Gaudino, Mario, Weinsaft, Jonathan W.

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Baseline Intraoperative Left Ventricular Diastolic Function Is Associated with Postoperative Atrial Fibrillation after Cardiac Surgery von Rong, Lisa Q, Di Franco, Antonino, Rahouma, Mohammed, Dimagli, Arnaldo, Patel, Aneri, Lopes, Alexandra J, Walline, Maria, Chan, June, Chadow, David, Olaria, Roberto Perezgrovas, Soletti, Giovanni, Kim, Jiwon, Devereux, Richard B, Pryor, Kane O, Girardi, Leonard N, Weinsaft, Jonathan W, Gaudino, Mario

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Postoperative pericardial effusion, pericardiotomy, and atrial fibrillation: An explanatory analysis of the PALACS trial von Rong, Lisa Q., Di Franco, Antonino, Rahouma, Mohamed, Dimagli, Arnaldo, Chan, June, Lopes, Alexandra J., Kim, Jiwon, Sanna, Tommaso, Devereux, Richard B., Delgado, Victoria, Weinsaft, Jonathan W., Crea, Filippo, Alexander, John H., Gillinov, Marc, DiMaio, John Michael, Pryor, Kane O., Girardi, Leonard, Gaudino, Mario

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Occurrence, populations, diversity, and growth potential of spore-forming bacteria in “requeijão cremoso” von Oliveira, Rodrigo B.A., Lopes, Letícia S., Baptista, Rafaela C., Chincha, Alexandra A.I.A., Portela, Jéssica B., Nascimento, Janaina S., Costa, Leonardo E.O., Cruz, Adriano G., Sant’Ana, Anderson S.

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