Comprehensive evolution and molecular characteristics of a large number of SARS-CoV-2 genomes reveal its epidemic trends von Bai, Yunmeng, Jiang, Dawei, Lon, Jerome R, Chen, Xiaoshi, Hu, Meiling, Lin, Shudai, Chen, Zixi, Wang, Xiaoning, Meng, Yuhuan, Du, Hongli

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AutoVEM: An automated tool to real-time monitor epidemic trends and key mutations in SARS-CoV-2 evolution von Xi, Binbin, Jiang, Dawei, Li, Shuhua, Lon, Jerome R., Bai, Yunmeng, Lin, Shudai, Hu, Meiling, Meng, Yuhuan, Qu, Yimo, Huang, Yuting, Liu, Wei, Huang, Lizhen, Du, Hongli

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease von Barrett, Jeffrey C, Hansoul, Sarah, Nicolae, Dan L, Cho, Judy H, Duerr, Richard H, Rioux, John D, Brant, Steven R, Silverberg, Mark S, Taylor, Kent D, Barmada, M Michael, Bitton, Alain, Dassopoulos, Themistocles, Datta, Lisa Wu, Green, Todd, Griffiths, Anne M, Kistner, Emily O, Murtha, Michael T, Regueiro, Miguel D, Rotter, Jerome I, Schumm, L Philip, Steinhart, A Hillary, Targan, Stephan R, Xavier, Ramnik J, Libioulle, Cécile, Sandor, Cynthia, Lathrop, Mark, Belaiche, Jacques, Dewit, Olivier, Gut, Ivo, Heath, Simon, Laukens, Debby, Mni, Myriam, Rutgeerts, Paul, Van Gossum, André, Zelenika, Diana, Franchimont, Denis, Hugot, Jean-Pierre, de Vos, Martine, Vermeire, Severine, Louis, Edouard, Cardon, Lon R, Anderson, Carl A, Drummond, Hazel, Nimmo, Elaine, Ahmad, Tariq, Prescott, Natalie J, Onnie, Clive M, Fisher, Sheila A, Marchini, Jonathan, Ghori, Jilur, Bumpstead, Suzannah, Gwilliam, Rhian, Tremelling, Mark, Deloukas, Panos, Mansfield, John, Jewell, Derek, Satsangi, Jack, Mathew, Christopher G, Parkes, Miles, Georges, Michel, Daly, Mark J

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High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease: A Randomized Controlled Trial von Aisen, Paul S, Schneider, Lon S, Sano, Mary, Diaz-Arrastia, Ramon, van Dyck, Christopher H, Weiner, Myron F, Bottiglieri, Teodoro, Jin, Shelia, Stokes, Karen T, Thomas, Ronald G, Thal, Leon J, Alzheimer Disease Cooperative Study, for the

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Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease von Pichet Binette, Alexa, Franzmeier, Nicolai, Spotorno, Nicola, Ewers, Michael, Brendel, Matthias, Biel, Davina, Strandberg, Olof, Janelidze, Shorena, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Smith, Ruben, Stomrud, Erik, Ossenkoppele, Rik, Hansson, Oskar

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Non-coding variability at the APOE locus contributes to the Alzheimer’s risk von Zhou, Xiaopu, Chen, Yu, Mok, Kin Y., Kwok, Timothy C. Y., Mok, Vincent C. T., Guo, Qihao, Ip, Fanny C., Chen, Yuewen, Mullapudi, Nandita, Giusti-Rodríguez, Paola, Sullivan, Patrick F., Hardy, John, Fu, Amy K. Y., Li, Yun, Ip, Nancy Y.

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Type 2 diabetes mellitus, brain atrophy, and cognitive decline von Moran, Chris, Wang, Wei, Callisaya, Michele, Aisen, Paul, Jagust, William, Trojanowki, John Q, Beckett, Laurel, Green, Robert C, Saykin, Andrew J, Montine, Tom, Gamst, Anthony, Gessert, Devon, Kornak, John, Alexander, Gene, DeCarli, Charles, Bandy, Dan, Koeppe, Robert A, Mathis, Chet, Cairns, Nigel J, Taylor-Reinwald, Lisa, Trojanowki, J.Q, Korecka, Magdalena, Neu, Scott, Foroud, Tatiana M, Potkin, Steven, Shen, Li, Frank, Richard, Kaye, Jeffrey, Dolen, Sara, Pawluczyk, Sonia, Spann, Bryan M, Brewer, James, Lord, Joanne L, Chowdhury, Munir, Bell, Karen L, Morris, John C, Leon, Sue, Schneider, Stacy, deToledo-Morrell, Leyla, Shah, Raj C, Albert, Marilyn, Onyike, Chiadi, Kielb, Stephanie, Rusinek, Henry, Doraiswamy, P Murali, Coleman, R Edward, Wolk, David, Jicha, Greg, Oakley, MaryAnn, Simpson, Donna M, Porsteinsson, Anton P, McAdams-Ortiz, Catherine, Womack, Kyle, Martin-Cook, Kristen, Lah, James J, Burns, Jeffrey M, Anderson, Heather S, Silverman, Daniel H.S, Graff-Radford, Neill R, Johnson, Heather, Farlow, Martin R, Hake, Ann Marie, Matthews, Brandy R, Herring, Scott, Carson, Richard E, MacAvoy, Martha G, Hosein, Chris, Caldwell, Curtis, Mudge, Benita, Rogers, John, Kerwin, Diana, Mesulam, Marek-Marsel, Taylor, Joy L, Tinklenberg, Jared, Sabbagh, Marwan, Kowall, Neil, Killiany, Ronald, Bwayo, Salome K, Lerner, Alan, Hudson, Leon, Ogrocki, Paula, Bartha, Dr Rob, Johnson, Sterling, Asthana, Sanjay, Scharre, Douglas W, Zimmerman, Earl A, Brown, Alice D, Pearlson, Godfrey D, Blank, Karen, Santulli, Robert B, Williamson, Jeff D, Ott, Brian R, Correia, Stephen, Rachinsky, Irina, Drost, Dick, Hernando, Raymundo, Sarrael, Antero, Shim, Hyungsub, Chaing, Gloria, Smith, Amanda

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Common variants at five new loci associated with early-onset inflammatory bowel disease von Hakonarson, Hakon, Zhang, Haitao, Grand, Richard, Hou, Cuiping, Silverberg, Mark S, Muise, Aleixo, Stephens, Michael, Annese, Vito, Grundmeier, Robert, Russell, Richard K, Lee, Jessica, Daly, Mark, Griffiths, Anne, Heyman, Melvin B, Latiano, Anna, Kirschner, Barbara, Imielinski, Marcin, Baldassano, Robert N, Cucchiara, Salvatore, Grant, Struan F A, Flory, James H, Monos, Dimitri S, Saeed, Shehzad, Chiavacci, Rosetta M, Bradfield, Jonathan P, Dallapiccola, Bruno, Denson, Lee, Taylor, Kent, McGovern, Dermot, Dubinsky, Marla, Levine, Arie, Castro, Massimo, Abrams, Debra J, Kugathasan, Subra, Otieno, George, Walters, Thomas D, Frackelton, Edward C, Sleiman, Patrick, Van Limbergen, Johan, Wilson, David C, Essers, Jonah, Glessner, Joseph T, Stempak, Joanne, Guthery, Stephen L, Satsangi, Jack, Ferry, George D, Piccoli, David, Wang, Kai, Kim, Cecilia E

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The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory von Franzmeier, Nicolai, Rubinski, Anna, Neitzel, Julia, Ewers, Michael

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Chronic divalproex sodium use and brain atrophy in Alzheimer disease von FLEISHER, A. S, TRURAN, D, TARIOT, P. N, MAI, J. T, LANGBAUM, J. B. S, AISEN, P. S, CUMMINGS, J. L, JACK, C. R, WEINER, M. W, THOMAS, R. G, SCHNEIDER, L. S

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Tau‐Atrophy Variability Reveals Phenotypic Heterogeneity in Alzheimer's Disease von McCollum, Lauren, Jack, Clifford R., Thomas, Ronald G., Walter, Sarah, Sather, Tamie, Donohue, Michael, Bernstein, Matthew, Borowski, Bret, Kantarci, Kejal, Ward, Chad, Koeppe, Robert A., Mathis, Chet, Cairns, Nigel J., Korecka, Magdalena, Figurski, Michal, Crawford, Karen, Snyder, Peter J., Molchan, Susan, Lind, Betty, Dolen, Sara, Spann, Bryan M., Vanderswag, Helen, Fleisher, Adam, Rountree, Susan, Dang, Mimi, Honig, Lawrence S., Leon, Sue, Mintun, Mark A., Schneider, Stacy, Clark, David, Brockington, John, Roberson, Erik, Albert, Marilyn, Kielb, Stephanie, Michel, Christina A., Leon, Mony J, De Santi, Susan, Wolk, David, Smith, Charles D., Jicha, Greg, Oates, Elizabeth, Conrad, Gary, Lopez, Oscar L., Oakley, MaryAnn, Goldstein, Bonnie S., Martin, Kim, Makino, Kelly M., Mulnard, Ruth A., Ortiz, Catherine Mc Adams, Womack, Kyle, Quiceno, Mary, Arrastia, Ramon Diaz, Weiner, Myron, DeVous, Michael, Cellar, Janet S., Bums, Jeffrey M., Anderson, Heather S., Woo, Ellen, Parfitt, Francine, Kendall, Tracy, Johnson, Heather, Hake, Ann Marie, Hunt, Cynthia, Carson, Richard E., MacAvoy, Martha G., Bergman, Howard, Stefanovic, Bojana, Feldman, Howard, Assaly, Michele, Kertesz, Andrew, Rogers, John, Trost, Dick, Wu, Chuang Kuo, Johnson, Keith A., Marshall, Gad, Taylor, Joy L., Lane, Barton, Rosen, Allison, Belden, Christine M., Kowall, Neil, Norbash, Alexan, Hudson, Leon, Olichney, John, Lee, T Y, Bartha, Rob, Johnson, Sterling, Asthana, Sanjay, Capote, Horacio, Williamson, Jeff D., Watkins, Franklin, Salloway, Stephen, Malloy, Paul, Rosen, Howard J., Miller, Bruce L., Mintzer, Jacobo, Bachman, David, Finger, Elizabether, Rogers, John, Kertesz, Andrew, Fargher, Kristin

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Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease von Hu, William T., Ozturk, Tugba, Kollhoff, Alexander, Wharton, Whitney, Christina Howell, J.

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Vascular burden and Alzheimer disease pathologic progression von Lo, Raymond Y., Jagust, William J., Weiner, Michael, Petersen, Ronald, Jack, Clifford R., Trojanowki, John Q., Toga, Arthur W., Green, Robert C., Donohue, Michael, Sather, Tamie, Harvey, Danielle, Dale, Anders, Bernstein, Matthew, Felmlee, Joel, Fox, Nick, Thompson, Paul, Koeppe, Robert A., Chen, Kewei, Cairns, Nigel J., Shaw, Les, Foroud, Tatiana M., Potkin, Steven, Kachaturian, Zaven, Snyder, Peter J., Quinn, Joseph, Lind, Betty, Schneider, Lon S., Vanderswag, Helen, Johnson, Kris, Doody, Rachelle S., Bell, Karen L., Ances, Beau, Carroll, Maria, Mintun, Mark A., Schneider, Stacy, Griffith, Randall, Mitsis, Effie, Romirowsky, Aliza, Varon, Daniel, Roberts, Peggy, De Santi, Susan, Doraiswamy, P. Murali, Arnold, Steven E., Karlawish, Jason H., Smith, Charles D., Porsteinsson, Anton P., Martin, Kim, Ismail, M. Saleem, Brand, Connie, Mathews, Dana, Quiceno, Mary, Weiner, Myron, DeVous, Michael, Levey, Allan I., Lah, James J., Burns, Jeffrey M., Swerdlow, Russell H., Bartzokis, George, Silverman, Daniel H.S., Graff-Radford, Neill R, Johnson, Heather, Caldwell, Curtis, Assaly, Michele, Kertesz, Andrew, Bernick, Charles, Mesulam, Marek-Marsel, Lipowski, Kristina, Wu, Chuang-Kuo, Turner, Raymond Scott, Johnson, Kathleen, Reynolds, Brigid, Lane, Barton, Jacobson, Sandra, Budson, Andrew E., Johnson, Patricia Lynn, Obisesan, Thomas O., Wolday, Saba, Bwayo, Salome K., Lerner, Alan, Fletcher, Evan, Carmichael, Owen, Kittur, Smita, Bartha, Dr Rob, Preda, Adrian, Tariot, Pierre, Fleisher, Adam, Reeder, Stephanie, Capote, Horacio, Kataki, Maria, Celmins, Dzintra, Pearlson, Godfrey D., Anderson, Karen, Santulli, Robert B., Sink, Kaycee M., Garg, Pradeep, Ott, Brian R., Malloy, Paul, Mintzer, Jacobo, Spicer, Kenneth, Finger, Elizabether

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Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort von Oka, Takaki, Matsuzawa, Yuki, Tsuneyoshi, Momoka, Nakamura, Yoshitaka, Aoshima, Ken, Tsugawa, Hiroshi

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Author Correction: Predicting Alzheimer’s disease progression using multi-modal deep learning approach von Lee, Garam, Nho, Kwangsik, Kang, Byungkon, Sohn, Kyung-Ah, Kim, Dokyoon

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Associations between neuropsychiatric symptoms of affective and vegetative domains and brain morphology in aging people with mild cognitive impairment and Alzheimer's disease von Cannizzaro, Adriana, Aisen, Paul, Weiner, Michael, Petersen, Ronald, Jack, Clifford R., Green, Robert C., Petersen, Ronald, Beckett, Laurel, Fox, Nick, Alexander, Gene, DeCarli, Charles, Jagust, William, Bandy, Dan, Foster, Norm, Taylor‐Reinwald, Lisa, Trojanowki, J. Q., Lee, Virginia M. Y., Korecka, Magdalena, Toga, Arthur W., Crawford, Karen, Neu, Scott, Kachaturian, Zaven, Frank, Richard, Snyder, Peter J., Kaye, Jeffrey, Quinn, Joseph, Pawluczyk, Sonia, Spann, Bryan M., Heidebrink, Judith L., Lord, Joanne L., Petersen, Ronald, Johnson, Kris, Ances, Beau, Carroll, Maria, Schneider, Stacy, Varon, Daniel, Roberts, Peggy, Albert, Marilyn, Rusinek, Henry, Santi, Susan, Arnold, Steven E., Goldstein, Bonnie S., Martin, Kim, Makino, Kelly M., Ismail, M. Saleem, Brand, Connie, Mulnard, Ruth A., Mc‐Adams‐Ortiz, Catherine, Mathews, Dana, Diaz‐Arrastia, Ramon, Martin‐Cook, Kristen, DeVous, Michael, Levey, Allan I., Anderson, Heather S., Swerdlow, Russell H., Lu, Po H., Bartzokis, George, Silverman, Daniel H. S., Graff‐Radford, Neill R., Johnson, Heather, Farlow, Martin R., Matthews, Brandy R., Dyck, Christopher H., Carson, Richard E., Bergman, Howard, Stefanovic, Bojana, Feldman, Howard, Kertesz, Andrew, Lipowski, Kristina, Martinez, Walter, Johnson, Kathleen, Sperling, Reisa A., Marshall, Gad, Lane, Barton, Belden, Christine, Budson, Andrew E., Norbash, Alexander, Johnson, Patricia Lynn, Fletcher, Evan, Carmichael, Owen, Olichney, John, Tariot, Pierre, Bates, Vernice, Capote, Horacio, Zimmerman, Earl A., Celmins, Dzintra, Blank, Karen, Schwartz, Eben S., Sink, Kaycee M., Williamson, Jeff D., Querfurth, Henry, Mintzer, Jacobo, Rachinsky, Irina, Drost, Dick, Pomara, Nunzio, Sarrael, Antero, Schultz, Susan K., Boles Ponto, Laura L., Shim, Hyungsub, Smith, Karen Elizabeth

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Author Correction: FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease von Yan, Tingxiang, Liang, Jingjing, Gao, Ju, Wang, Luwen, Fujioka, Hisashi, Zhu, Xiaofeng, Wang, Xinglong

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Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia von Schilling, Lucas Porcello, Pascoal, Tharick A., Zimmer, Eduardo R., Mathotaarachchi, Sulantha, Shin, Monica, de Mello Rieder, Carlos Roberto, Gauthier, Serge, Palmini, André, Rosa-Neto, Pedro

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Polygenic effects on the risk of Alzheimer's disease in the Japanese population von Kikuchi, Masataka, Miyashita, Akinori, Hara, Norikazu, Kasuga, Kensaku, Saito, Yuko, Murayama, Shigeo, Kakita, Akiyoshi, Akatsu, Hiroyasu, Ozaki, Kouichi, Niida, Shumpei, Kuwano, Ryozo, Iwatsubo, Takeshi, Nakaya, Akihiro, Ikeuchi, Takeshi

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Correction: Polygenic effects on the risk of Alzheimer's disease in the Japanese population von Kikuchi, Masataka, Miyashita, Akinori, Hara, Norikazu, Kasuga, Kensaku, Saito, Yuko, Murayama, Shigeo, Kakita, Akiyoshi, Akatsu, Hiroyasu, Ozaki, Kouichi, Niida, Shumpei, Kuwano, Ryozo, Iwatsubo, Takeshi, Nakaya, Akihiro, Ikeuchi, Takeshi

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