CD74 is a novel transcription regulator von Gil-Yarom, Naama, Radomir, Lihi, Sever, Lital, Kramer, Matthias P., Lewinsky, Hadas, Bornstein, Chamutal, Blecher-Gonen, Ronnie, Barnett-Itzhaki, Zohar, Mirkin, Vita, Friedlander, Gilgi, Shvidel, Lev, Herishanu, Yair, Lolis, Elias J., Becker-Herman, Shirly, Amit, Ido, Shachar, Idit

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Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose von Bloom, Joshua, Pantouris, Georgios, He, Mingzhu, Aljabari, Bayan, Mishra, Lopa, Manjula, Ramu, Parkins, Andrew, Lolis, Elias J, Al-Abed, Yousef

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Unraveling the mechanism of recognition of the 3 ' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60 von Hsiao, Hsin-hao T., Crichlow, Gregg V., Murphy, James W., Folta-Stogniew, Ewa J., Lolis, Elias J., Braddock, Demetrios T.

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Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast von Cho, Yoonsang, Crichlow, Gregg V., Vermeire, Jon J., Leng, Lin, Du, Xin, Hodsdon, Michael E., Bucala, Richard, Cappello, Michael, Gross, Matt, Gaeta, Federico, Johnson, Kirk, Lolis, Elias J., Petsko, Gregory A.

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MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations von Fan, Chengpeng, Rajasekaran, Deepa, Syed, Mansoor Ali, Leng, Lin, Loria, J. Patrick, Bhandari, Vineet, Bucala, Richard, Lolis, Elias J.

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Structural Plasticity in the C‑Terminal Region of Macrophage Migration Inhibitory Factor‑2 Is Associated with an Induced Fit Mechanism for a Selective Inhibitor von Pantouris, Georgios, Bucala, Richard, Lolis, Elias J

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Conformational dynamics of Ca2+-dependent responses in the polycystin-2 C-terminal tail von Yang, Yifei, Hodsdon, Michael E, Lolis, Elias J, Ehrlich, Barbara E

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Engineering of the high-affinity chemokine CXCL13 to screen CXCR5 antagonists to treat cancer and autoimmune diseases von Ramu, Manjula, Rosenberg, Eric, Kartz, Sam, Foss, Francine, Lolis, Elias J.

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Targeting distinct tautomerase sites of D‐DT and MIF with a single molecule for inhibition of neutrophil lung recruitment von Rajasekaran, Deepa, Zierow, Swen, Syed, Mansoor, Bucala, Richard, Bhandari, Vineet, Lolis, Elias J.

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A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies von Skeens, Erin, Pantouris, Georgios, Shah, Dilip, Manjula, Ramu, Ombrello, Michael J, Maluf, N Karl, Bhandari, Vineet, Lisi, George P, Lolis, Elias J

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Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel von Pantouris, Georgios, Khurana, Leepakshi, Ma, Anthony, Skeens, Erin, Reiss, Krystle, Batista, Victor S., Lisi, George P., Lolis, Elias J.

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Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation von Kulkarni, Mandar V., Tettamanzi, M. Cristina, Murphy, James W., Keeler, Camille, Myszka, David G., Chayen, Naomi E., Lolis, Elias J., Hodsdon, Michael E.

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Nanosecond Dynamics Regulate the MIF‐Induced Activity of CD74 von Pantouris, Georgios, Ho, Junming, Shah, Dilip, Syed, Mansoor Ali, Leng, Lin, Bhandari, Vineet, Bucala, Richard, Batista, Victor S., Loria, J. Patrick, Lolis, Elias J.

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Mapping N- to C-terminal allosteric coupling through disruption of a putative CD74 activation site in D-dopachrome tautomerase von Chen, Emily, Widjaja, Vinnie, Kyro, Gregory, Allen, Brandon, Das, Pragnya, Prahaladan, Varsha M., Bhandari, Vineet, Lolis, Elias J., Batista, Victor S., Lisi, George P.

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The N‐terminal length and side‐chain composition of CXCL13 affect crystallization, structure and functional activity von Rosenberg, Eric M., Herrington, James, Rajasekaran, Deepa, Murphy, James W., Pantouris, Georgios, Lolis, Elias J.

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A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase von Chen, Emily, Reiss, Krystle, Shah, Dilip, Manjula, Ramu, Allen, Brandon, Murphy, Eva L., Murphy, James W., Batista, Victor S., Bhandari, Vineet, Lolis, Elias J., Lisi, George P.

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Expression, purification and crystallization of the novel Xenopus tropicalis ALDH16B1, a homologue of human ALDH16A1 von Pantouris, Georgios, Dioletis, Evangelos, Chen, Ying, Thompson, David C., Vasiliou, Vasilis, Lolis, Elias J.

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Allosteric peptide regulators of chemokine receptors CXCR4 and CXCR7 von Ehrlich, Anna, Ray, Paramita, Luker, Kathryn E., Lolis, Elias J., Luker, Gary D.

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Structural Interactions Dictate the Kinetics of Macrophage Migration Inhibitory Factor Inhibition by Different Cancer-Preventive Isothiocyanates von Crichlow, Gregg V, Fan, Chengpeng, Keeler, Camille, Hodsdon, Michael, Lolis, Elias J

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Characterization, Dynamics, and Mechanism of CXCR4 Antagonists on a Constitutively Active Mutant von Rosenberg, Eric M., Harrison, Reed E.S., Tsou, Lun Kelvin, Drucker, Natalie, Humphries, Brock, Rajasekaran, Deepa, Luker, Kathryn E., Wu, Chien-Huang, Song, Jen-Shin, Wang, Chuan-Jen, Murphy, James W., Cheng, Yung-Chi, Shia, Kak-Shan, Luker, Gary D., Morikis, Dimitrios, Lolis, Elias J.

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