Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity von Schäfer, Nicola, Lohmann, Christine, Winnik, Stephan, van Tits, Lambertus J, Miranda, Melroy X, Vergopoulos, Athanasios, Ruschitzka, Frank, Nussberger, Jürg, Berger, Stefan, Lüscher, Thomas F, Verrey, François, Matter, Christian M

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The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression von Miranda, Melroy X, van Tits, Lambertus J, Lohmann, Christine, Arsiwala, Tasneem, Winnik, Stephan, Tailleux, Anne, Stein, Sokrates, Gomes, Ana P, Suri, Vipin, Ellis, James L, Lutz, Thomas A, Hottiger, Michael O, Sinclair, David A, Auwerx, Johan, Schoonjans, Kristina, Staels, Bart, Lüscher, Thomas F, Matter, Christian M

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Endothelial overexpression of LOX-1 increases plaque formation and promotes atherosclerosis in vivo von Akhmedov, Alexander, Rozenberg, Izabela, Paneni, Francesco, Camici, Giovanni G, Shi, Yi, Doerries, Carola, Sledzinska, Anna, Mocharla, Pavani, Breitenstein, Alexander, Lohmann, Christine, Stein, Sokrates, von Lukowicz, Tobias, Kurrer, Michael O, Borén, Jan, Becher, Burkhard, Tanner, Felix C, Landmesser, Ulf, Matter, Christian M, Lüscher, Thomas F

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Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata von Brokopp, Chad E., Schoenauer, Roman, Richards, Peter, Bauer, Stefan, Lohmann, Christine, Emmert, Maximilian Y., Weber, Benedikt, Winnik, Stephan, Aikawa, Elena, Graves, Kirk, Genoni, Michele, Vogt, Peter, Lüscher, Thomas F., Renner, Christoph, Hoerstrup, Simon P., Matter, Christian M.

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Systemic VEGF inhibition accelerates experimental atherosclerosis and disrupts endothelial homeostasis – implications for cardiovascular safety von Winnik, Stephan, Lohmann, Christine, Siciliani, Giovanni, von Lukowicz, Tobias, Kuschnerus, Kira, Kraenkel, Nicolle, Brokopp, Chad E, Enseleit, Frank, Michels, Stephan, Ruschitzka, Frank, Lüscher, Thomas F, Matter, Christian M

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Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells von Rajalingam, Krishnaraj, Sharma, Manu, Lohmann, Christine, Oswald, Monique, Thieck, Oliver, Froelich, Christopher J, Rudel, Thomas

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Endothelial LOX-1 activation differentially regulates arterial thrombus formation depending on oxLDL levels: role of the Oct-1/SIRT1 and ERK1/2 pathways von Akhmedov, Alexander, Camici, Giovanni G, Reiner, Martin F, Bonetti, Nicole R, Costantino, Sarah, Holy, Erik W, Spescha, Remo D, Stivala, Simona, Schaub Clerigué, Ariane, Speer, Thimoteus, Breitenstein, Alexander, Manz, Jasmin, Lohmann, Christine, Paneni, Francesco, Beer, Juerg-Hans, Lüscher, Thomas F

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Sirt1 inhibition promotes in vivo arterial thrombosis and tissue factor expression in stimulated cells von BREITENSTEIN, Alexander, STEIN, Sokrates, LÜSCHER, Thomas F, TANNER, Felix C, HOLY, Erik W, CAMICI, Giovanni G, LOHMANN, Christine, AKHMEDOV, Alexander, SPESCHA, Remo, ELLIOTT, Peter J, WESTPHAL, Christoph H, MATTER, Christian M

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SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice von Stein, Sokrates, Schäfer, Nicola, Breitenstein, Alexander, Besler, Christian, Winnik, Stephan, Lohmann, Christine, Heinrich, Kathrin, Brokopp, Chad E, Handschin, Christoph, Landmesser, Ulf, Tanner, Felix C, Lüscher, Thomas F, Matter, Christian M

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Sex differences in the long-term prognostic value of 13N-ammonia myocardial perfusion positron emission tomography von Gebhard, Catherine, Fiechter, Michael, Herzog, Bernhard A., Lohmann, Christine, Bengs, Susan, Treyer, Valerie, Messerli, Michael, Benz, Dominik C., Giannopoulos, Andreas A., Gräni, Christoph, Pazhenkottil, Aju P., Buechel, Ronny R., Kaufmann, Philipp A.

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Age- and sex-dependent changes in sympathetic activity of the left ventricular apex assessed by 18F-DOPA PET imaging von Burger, Irene A, Lohmann, Christine, Messerli, Michael, Bengs, Susan, Becker, Anton, Maredziak, Monika, Treyer, Valerie, Haider, Ahmed, Schwyzer, Moritz, Benz, Dominik C, Kudura, Ken, Fiechter, Michael, Giannopoulos, Andreas A, Fuchs, Tobias A, Gräni, Christoph, Pazhenkottil, Aju P, Gaemperli, Oliver, Buechel, Ronny R, Kaufmann, Philipp A, Gebhard, Catherine

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ApoE-/- PGC-1α-/- mice display reduced IL-18 levels and do not develop enhanced atherosclerosis von Stein, Sokrates, Lohmann, Christine, Handschin, Christoph, Stenfeldt, Elin, Borén, Jan, Lüscher, Thomas F, Matter, Christian M

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Aging Induces Endothelial Dysfunction While Sparing Arterial Thrombosis von Stämpfli, Simon F, Akhmedov, Alexander, Gebhard, Cathérine, Lohmann, Christine, Holy, Erik W, Rozenberg, Izabela, Spescha, Remo, Shi, Yi, Lüscher, Thomas F, Tanner, Felix C, Camici, Giovanni G

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Role of endogenous fas (CD95/Apo-1) ligand in balloon-induced apoptosis, inflammation, and neointima formation von MATTER, Christian M, CHADJICHRISTOS, Christos E, KWAK, Brenda R, LÜSCHER, Thomas F, MEIER, Patricia, VON LUKOWICZ, Tobias, LOHMANN, Christine, SCHULER, Pia K, DONGMING ZHANG, ODERMATT, Bernhard, HOFMANN, Eugen, BRUNNER, Thomas

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Increased balloon-induced inflammation, proliferation, and neointima formation in apolipoprotein E (ApoE) knockout mice von MATTER, Christian M, LIMING MA, HERMANN, Dirk M, LÜSCHER, Thomas F, VON LUKOWICZ, Tobias, MEIER, Patricia, LOHMANN, Christine, DONGMING ZHANG, KILIC, Ülkan, HOFMANN, Eugen, HA, Suk-Woo, HERSBERGER, Martin

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Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis von Klingenberg, Roland, Gerdes, Norbert, Badeau, Robert M, Gisterå, Anton, Strodthoff, Daniela, Ketelhuth, Daniel F J, Lundberg, Anna M, Rudling, Mats, Nilsson, Stefan K, Olivecrona, Gunilla, Zoller, Stefan, Lohmann, Christine, Lüscher, Thomas F, Jauhiainen, Matti, Sparwasser, Tim, Hansson, Göran K

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SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis von Stein, Sokrates, Lohmann, Christine, Schäfer, Nicola, Hofmann, Janin, Rohrer, Lucia, Besler, Christian, Rothgiesser, Karin M., Becher, Burkhard, Hottiger, Michael O., Borén, Jan, McBurney, Michael W., Landmesser, Ulf, Lüscher, Thomas F., Matter, Christian M.

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Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity von Gaul, Daniel S, Weber, Julien, van Tits, Lambertus J, Sluka, Susanna, Pasterk, Lisa, Reiner, Martin F, Calatayud, Natacha, Lohmann, Christine, Klingenberg, Roland, Pahla, Jürgen, Vdovenko, Daria, Tanner, Felix C, Camici, Giovanni G, Eriksson, Urs, Auwerx, Johan, Mach, François, Windecker, Stephan, Rodondi, Nicolas, Lüscher, Thomas F, Winnik, Stephan, Matter, Christian M

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Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation von Winnik, Stephan, Lohmann, Christine, Richter, Eva K., Schäfer, Nicola, Song, Wen-Liang, Leiber, Florian, Mocharla, Pavani, Hofmann, Janin, Klingenberg, Roland, Borén, Jan, Becher, Burkhard, FitzGerald, Garret A., Lüscher, Thomas F., Matter, Christian M., Beer, Jürg H.

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Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular... von Winnik, Stephan, Gaul, Daniel S., Preitner, Frédéric, Lohmann, Christine, Weber, Julien, Miranda, Melroy X., Liu, Yilei, van Tits, Lambertus J., Mateos, José María, Brokopp, Chad E., Auwerx, Johan, Thorens, Bernard, Lüscher, Thomas F., Matter, Christian M.

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