MK-801 disrupts and nicotine augments 40 Hz auditory steady state responses in the auditory cortex of the urethane-anesthetized rat von Sivarao, Digavalli V., Frenkel, Mikhail, Chen, Ping, Healy, Francine L., Lodge, Nicholas J., Zaczek, Robert

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The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia von Bristow, Linda J, Easton, Amy E, Li, Yu-Wen, Sivarao, Digavalli V, Lidge, Regina, Jones, Kelli M, Post-Munson, Debra, Daly, Christopher, Lodge, Nicholas J, Gallagher, Lizbeth, Molski, Thaddeus, Pieschl, Richard, Chen, Ping, Hendricson, Adam, Westphal, Ryan, Cook, James, Iwuagwu, Christiana, Morgan, Daniel, Benitex, Yulia, King, Dalton, Macor, John E, Zaczek, Robert, Olson, Richard

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Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents von Pieschl, Rick L., Miller, Regina, Jones, Kelli M., Post-Munson, Debra J., Chen, Ping, Newberry, Kimberly, Benitex, Yulia, Molski, Thaddeus, Morgan, Daniel, McDonald, Ivar M., Macor, John E., Olson, Richard E., Asaka, Yukiko, Digavalli, Siva, Easton, Amy, Herrington, James, Westphal, Ryan S., Lodge, Nicholas J., Zaczek, Robert, Bristow, Linda J., Li, Yu-Wen

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Biochemical and behavioral effects of PDE10A inhibitors: Relationship to target site occupancy von Li, Yu-Wen, Seager, Matthew A., Wojcik, Trevor, Heman, Karen, Molski, Thaddeus F., Fernandes, Alda, Langdon, Shaun, Pendri, Annapurna, Gerritz, Samuel, Tian, Yuan, Hong, Yang, Gallagher, Lizbeth, Merritt, James R., Zhang, Chongwu, Westphal, Ryan, Zaczek, Robert, Macor, John E., Bronson, Joanne J., Lodge, Nicholas J.

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Monoamine reuptake site occupancy of sibutramine: Relationship to antidepressant-like and thermogenic effects in rats von Li, Yu-Wen, Langdon, Shaun, Pieschl, Rick, Strong, Todd, Wright, Robert N., Rohrbach, Kenneth, Lelas, Snjezana, Lodge, Nicholas J.

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Synthesis and evaluation of carbamate and aryl ether substituted pyrazinones as corticotropin releasing factor-1 (CRF1) receptor antagonists von Ahuja, Vijay T., Hartz, Richard A., Molski, Thaddeus F., Mattson, Gail K., Lentz, Kimberley A., Grace, James E., Lodge, Nicholas J., Bronson, Joanne J., Macor, John E.

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Pharmacological and behavioral characterization of the novel CRF1 antagonist BMS-763534 von Lodge, Nicholas J., Lelas, Snjezana, Li, Yu-Wen, Molski, Thaddeus, Grace, James, Sivarao, Digavalli V., Post-Munson, Debra, Healy, Francine, Bronson, Joanne J., Hartz, Richard, Macor, John E., Zaczek, Robert

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Synthesis and evaluation of prodrugs of corticotropin-releasing factor-1 (CRF1) receptor antagonist BMS-665053 leading to improved oral bioavailability von Hartz, Richard A., Vrudhula, Vivekananda M., Ahuja, Vijay T., Grace, James E., Lodge, Nicholas J., Bronson, Joanne J., Macor, John E.

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A Strategy to Minimize Reactive Metabolite Formation: Discovery of (S)-4-(1-Cyclopropyl-2-methoxyethyl)-6-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-5-oxo-4,5-dihydropyraz... von Hartz, Richard A, Ahuja, Vijay T, Zhuo, Xiaoliang, Mattson, Ronald J, Denhart, Derek J, Deskus, Jeffrey A, Vrudhula, Vivekananda M, Pan, Senliang, Ditta, Jonathan L, Shu, Yue-Zhong, Grace, James E, Lentz, Kimberley A, Lelas, Snjezana, Li, Yu-Wen, Molski, Thaddeus F, Krishnananthan, Subramaniam, Wong, Henry, Qian-Cutrone, Jingfang, Schartman, Richard, Denton, Rex, Lodge, Nicholas J, Zaczek, Robert, Macor, John E, Bronson, Joanne J

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NK1 receptor antagonism lowers occupancy requirement for antidepressant-like effects of SSRIs in the Gerbil forced swim test von Lelas, Snjezana, Li, Yu-Wen, Wallace-Boone, Tanya L., Taber, Matthew T., Newton, Amy E., Pieschl, Rick L., Davis, Carl D., Molski, Thaddeus F., Newberry, Kimberly S., Parker, Michael F., Gillman, Kevin W., Bronson, Joanne J., Macor, John E., Lodge, Nicholas J.

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Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels : Possible mechanism of cardioprotection von GARLID, K. D, PAUCEK, P, YAROV-YAROVOY, V, MURRAY, H. N, DARBENZIO, R. B, D'ALONZO, A. J, LODGE, N. J, SMITH, M. A, GROVER, G. J

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Synthesis and evaluation of candidate PET radioligands for corticotropin-releasing factor type-1 receptors von Lodge, Nicholas J, Li, Yu-Wen, Chin, Frederick T, Dischino, Douglas D, Zoghbi, Sami S, Deskus, Jeffrey A, Mattson, Ronald J, Imaizumi, Masao, Pieschl, Rick, Molski, Thaddeus F, Fujita, Masahiro, Dulac, Heidi, Zaczek, Robert, Bronson, Joanne J, Macor, John E, Innis, Robert B, Pike, Victor W

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Ex vivo assessment of binding site occupancy of monoamine reuptake inhibitors: Methodology and biological significance von Lengyel, Kelly, Pieschl, Rick, Strong, Todd, Molski, Thaddeus, Mattson, Gail, Lodge, Nicholas J., Li, Yu-Wen

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Biaryls as potent, tunable dual neurokinin 1 receptor antagonists and serotonin transporter inhibitors von Degnan, Andrew P., Tora, George O., Han, Ying, Rajamani, Ramkumar, Bertekap, Robert, Krause, Rudolph, Davis, Carl D., Hu, Joanna, Morgan, Daniel, Taylor, Sarah J., Krause, Kelly, Li, Yu-Wen, Mattson, Gail, Cunningham, Melissa A., Taber, Matthew T., Lodge, Nicholas J., Bronson, Joanne J., Gillman, Kevin W., Macor, John E.

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Behavioral and Pharmacological Validation of the Gerbil Forced-Swim Test: Effects of Neurokinin-1 Receptor Antagonists von Wallace-Boone, Tanya L, Newton, Amy E, Wright, Robert N, Lodge, Nicholas J, McElroy, John F

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BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia von King, Dalton, Iwuagwu, Christiana, Cook, Jim, McDonald, Ivar M, Mate, Robert, Zusi, F. Christopher, Hill, Matthew D, Fang, Haiquan, Zhao, Rulin, Wang, Bei, Easton, Amy E, Miller, Regina, Post-Munson, Debra, Knox, Ronald J, Gallagher, Lizbeth, Westphal, Ryan, Molski, Thaddeus, Fan, Jingsong, Clarke, Wendy, Benitex, Yulia, Lentz, Kimberley A, Denton, Rex, Morgan, Daniel, Zaczek, Robert, Lodge, Nicholas J, Bristow, Linda J, Macor, John E, Olson, Richard E

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Discovery of a novel series of quinolone α7 nicotinic acetylcholine receptor agonists von McDonald, Ivar M., Mate, Robert A., Zusi, F. Christopher, Huang, Hong, Post-Munson, Debra J., Ferrante, Meredith A., Gallagher, Lizbeth, Bertekap, Robert L., Knox, Ronald J., Robertson, Barbara J., Harden, David G., Morgan, Daniel G., Lodge, Nicholas J., Dworetzky, Steven I., Olson, Richard E., Macor, John E.

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Conformationally Restricted Homotryptamines. Part 7: 3-cis-(3-Aminocyclopentyl)indoles As Potent Selective Serotonin Reuptake Inhibitors von King, H. Dalton, Meng, Zhaoxing, Deskus, Jeffrey A, Sloan, Charles P, Gao, Qi, Beno, Brett R, Kozlowski, Edward S, LaPaglia, Melissa A, Mattson, Gail K, Molski, Thaddeus F, Taber, Matthew T, Lodge, Nicholas J, Mattson, Ronald J, Macor, John E

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Discovery of Indazoles as Potent, Orally Active Dual Neurokinin 1 Receptor Antagonists and Serotonin Transporter Inhibitors for the Treatment of Depression von Degnan, Andrew P, Tora, George O, Huang, Hong, Conlon, David A, Davis, Carl D, Hanumegowda, Umesh M, Hou, Xiaoping, Hsiao, Yi, Hu, Joanna, Krause, Rudolph, Li, Yu-Wen, Newton, Amy E, Pieschl, Rick L, Raybon, Joseph, Rosner, Thorsten, Sun, Jung-Hui, Taber, Matthew T, Taylor, Sarah J, Wong, Michael K, Zhang, Huiping, Lodge, Nicholas J, Bronson, Joanne J, Macor, John E, Gillman, Kevin W

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Chemical genetics reveals an RGS/G-protein role in the action of a compound von Fitzgerald, Kevin, Tertyshnikova, Svetlana, Moore, Lisa, Bjerke, Lynn, Burley, Ben, Cao, Jian, Carroll, Pamela, Choy, Robert, Doberstein, Steve, Dubaquie, Yves, Franke, Yvonne, Kopczynski, Jenny, Korswagen, Hendrik, Krystek, Stanley R, Lodge, Nicholas J, Plasterk, Ronald, Starrett, John, Stouch, Terry, Thalody, George, Wayne, Honey, van der Linden, Alexander, Zhang, Yongmei, Walker, Stephen G, Cockett, Mark, Wardwell-Swanson, Judi, Ross-Macdonald, Petra, Kindt, Rachel M

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