Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes von Herrera, B. M., Lockstone, H. E., Taylor, J. M., Ria, M., Barrett, A., Collins, S., Kaisaki, P., Argoud, K., Fernandez, C., Travers, M. E., Grew, J. P., Randall, J. C., Gloyn, A. L., Gauguier, D., McCarthy, M. I., Lindgren, C. M.

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Gene expression profiling in the adult Down syndrome brain von Lockstone, H.E., Harris, L.W., Swatton, J.E., Wayland, M.T., Holland, A.J., Bahn, S.

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Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells von Dolatshad, H, Pellagatti, A, Fernandez-Mercado, M, Yip, B H, Malcovati, L, Attwood, M, Przychodzen, B, Sahgal, N, Kanapin, A A, Lockstone, H, Scifo, L, Vandenberghe, P, Papaemmanuil, E, Smith, C W J, Campbell, P J, Ogawa, S, Maciejewski, J P, Cazzola, M, Savage, K I, Boultwood, J

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Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes von RYAN, M. M, LOCKSTONE, H. E, HUFLAKER, S. J, WAYLAND, M. T, WEBSTER, M. J, BAHN, S

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Independent protein-profiling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues von Huang, J T-J, Wang, L, Prabakaran, S, Wengenroth, M, Lockstone, H E, Koethe, D, Gerth, C W, Gross, S, Schreiber, D, Lilley, K, Wayland, M, Oxley, D, Leweke, F M, Bahn, S

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Expression Profiling of Fibroblasts Identifies Cell Cycle Abnormalities in Schizophrenia von Wang, L, Lockstone, H. E, Guest, P. C, Levin, Y, Palotás, A, Pietsch, S, Schwarz, E, Rahmoune, H, Harris, L. W, Ma, D, Bahn, S

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Effects of epigenetic pathway inhibitors on corticotroph tumour AtT20 cells von Lines, K E, Filippakopoulos, P, Stevenson, M, Müller, S, Lockstone, H E, Wright, B, Knapp, S, Buck, D, Bountra, C, Thakker, R V

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Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors von Lines, K E, Stevenson, M, Filippakopoulos, P, Müller, S, Lockstone, H E, Wright, B, Grozinsky-Glasberg, S, Grossman, A B, Knapp, S, Buck, D, Bountra, C, Thakker, R V

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Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells von Dolatshad, H, Pellagatti, A, Fernandez-Mercado, M, Yip, B H, Malcovati, L, Attwood, M, Przychodzen, B, Sahgal, N, Kanapin, A A, Lockstone, H, Scifo, L, Vandenberghe, P, Papaemmanuil, E, Smith, C W J, Campbell, P J, Ogawa, S, Maciejewski, J P, Cazzola, M, Savage, K I, Boultwood, J

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Transcriptional signature of human adipose tissue-derived stem cells (hASCs) preconditioned for chondrogenesis in hypoxic conditions von Pilgaard, L., Lund, P., Duroux, M., Lockstone, H., Taylor, J., Emmersen, J., Fink, T., Ragoussis, J., Zachar, V.

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Exon array data analysis using Affymetrix power tools and R statistical software von Lockstone, Helen E.

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Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations von Pellagatti, Andrea, Armstrong, Richard N., Steeples, Violetta, Sharma, Eshita, Repapi, Emmanouela, Singh, Shalini, Sanchi, Andrea, Radujkovic, Aleksandar, Horn, Patrick, Dolatshad, Hamid, Roy, Swagata, Broxholme, John, Lockstone, Helen, Taylor, Stephen, Giagounidis, Aristoteles, Vyas, Paresh, Schuh, Anna, Hamblin, Angela, Papaemmanuil, Elli, Killick, Sally, Malcovati, Luca, Hennrich, Marco L., Gavin, Anne-Claude, Ho, Anthony D., Luft, Thomas, Hellström-Lindberg, Eva, Cazzola, Mario, Smith, Christopher W.J., Smith, Stephen, Boultwood, Jacqueline

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Identification of Aberrant Splicing Events in Myelodysplastic Syndrome Patients with Splicing Factor Gene Mutations von Pellagatti, A, Steeples, V, Sharma, E, Repapi, E, Yip, B.H, Armstrong, R.N, Dolatshad, H, Lockstone, H, Taylor, S, Giagounidis, A, Vyas, P, Papaemmanuil, E, Woll, P, Killick, S, Malcovati, L, Hellström-Lindberg, E, Cazzola, M, Smith, C.W.J, Boultwood, J

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Expression of Idh1(R132H) in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis von Bardella, C., Al-Dalahmah, O., Krell, D., Brazauskas, P., Al-Qahtani, K., Tomkova, M., Adam, J., Serres, S., Lockstone, H., Freeman-Mills, L., Pfeffer, I., Sibson, N., Goldin, R., Schuster-Boeckler, B., Pollard, Patrick, Soga, T., McCullagh, J. S., Schofield, C. J., Mulholland, P., Ansorge, O., Kriaucionis, S., Ratcliffe, P. J., Szele, F. G., Tomlinson, I.

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Constructing custom-made radiotranscriptomic signatures from CT angiograms: an application in COVID-19 vascular inflammation von Kotanidis, C P, Xie, C, Siddique, M, Burnham, K, Lockstone, H, Kotronias, R, West, H, Rodrigues, J, Adlam, D, Neubauer, S, Channon, K, Deanfield, J, Ho, L P, Antoniades, C

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A human arterial transcriptomic signature predicts major adverse cardiac events and identifies novel, redox-related therapeutic targets within the vascular wall von Kotanidis, C P, Lockstone, H, Polkinghorne, M, Badi, I, Akoumianakis, I, Siddique, M, Antonopoulos, A, Evans, T, Farid, S, Srivastava, V, Krasopoulos, G, Sayeed, R, Channon, K M, Antoniades, C

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S77 Transcriptomic studies reveal monocyte-related genes as major contributor to disease activity in pulmonary sarcoidosis von Kendrick, Y, Crawshaw, A, Lockstone, H, Giannoulatou, E, Argoud, K, Taylor, S, Ho, LP

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S.21.04 - Glucocorticoid action in the brain: novel findings at the neuronal genome level von Reul, J.M.H.M., Kennedy, C.L.M., Salatino, S., Sharma, E., Engledow, S., Lockstone, H., Mifsud, K.R.

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Glucocorticoid action in the brain: novel findings at the neuronal genome level von Reul, J.M.H.M., Kennedy, C.L.M., Salatino, S., Sharma, E., Engledow, S., Lockstone, H., Mifsud, K.R.

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A mouse model with a frameshift mutation in the nuclear factor I/X (NFIX) gene has phenotypic features of Marshall-Smith syndrome von Kooblall, KG, Stevenson, M, Stewart, M, Harris, L, Zalucki, O, Dewhurst, H, Butterfield, N, Leng, H, Hough, TA, Ma, D, Siow, B, Potter, P, Cox, RD, Brown, SDM, Horwood, N, Wright, B, Lockstone, H, Buck, D, Vincent, TL, Hannan, FM, Bassett, JHD, Williams, GR, Lines, KE, Piper, M, Wells, S, Teboul, L, Hennekam, RC, Thakker, RV

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