Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator von Zalachoras, Ioannis, Houtman, René, Atucha, Erika, Devos, Rene, Tijssen, Ans M. I., Hu, Pu, Lockey, Peter M., Datson, Nicole A., Belanoff, Joseph K., Lucassen, Paul J., Joëls, Marian, de Kloet, E. Ronald, Roozendaal, Benno, Hunt, Hazel, Meijer, Onno C.

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A Virtual Screening Approach to Finding Novel and Potent Antagonists at the Melanin-Concentrating Hormone 1 Receptor von Clark, David E, Higgs, Christopher, Wren, Stephen P, Dyke, Hazel J, Wong, Melanie, Norman, Dennis, Lockey, Peter M, Roach, Alan G

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An Orally Bioavailable, Indole-3-glyoxylamide Based Series of Tubulin Polymerization Inhibitors Showing Tumor Growth Inhibition in a Mouse Xenograft Model of Head and Neck Cancer von Colley, Helen E, Muthana, Munitta, Danson, Sarah J, Jackson, Lucinda V, Brett, Matthew L, Harrison, Joanne, Coole, Sean F, Mason, Daniel P, Jennings, Luke R, Wong, Melanie, Tulasi, Vamshi, Norman, Dennis, Lockey, Peter M, Williams, Lynne, Dossetter, Alexander G, Griffen, Edward J, Thompson, Mark J

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Application of virtual screening to the discovery of novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with potential for the treatment of cancer and axonopathies von Clark, David E., Waszkowycz, Bohdan, Wong, Melanie, Lockey, Peter M., Adalbert, Robert, Gilley, Jonathan, Clark, Jonathan, Coleman, Michael P.

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From virtual to clinical: The discovery of PGN-1531, a novel antagonist of the prostanoid EP4 receptor von Sutton, Jon, Clark, David E., Higgs, Christopher, de Groot, Marcel J., Harris, Neil V., Taylor, Andrea, Lockey, Peter M., Maubach, Karen, Woodrooffe, Amanda, Davis, Richard J., Coleman, Robert A., Clark, Kenneth L.

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Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists von Cramp, Sue, Dyke, Hazel J., Higgs, Christopher, Clark, David E., Gill, Matthew, Savy, Pascal, Jennings, Neil, Price, Steve, Lockey, Peter M., Norman, Dennis, Porres, Soraya, Wilson, Francis, Jones, Alison, Ramsden, Nigel, Mangano, Raffaella, Leggate, Dan, Andersson, Marie, Hale, Richard

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Identification and optimisation of a series of substituted 5-(1 H-pyrazol-3-yl)-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors von Price, Steve, Bordogna, Walter, Bull, Richard J., Clark, David E., Crackett, Peter H., Dyke, Hazel J., Gill, Matthew, Harris, Neil V., Gorski, Julia, Lloyd, Julia, Lockey, Peter M., Mullett, Julia, Roach, Alan G., Roussel, Fabien, White, Anne B.

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Discovery and optimization of novel, non-steroidal glucocorticoid receptor modulators von Ray, Nicholas C., Clark, Robin D., Clark, David E., Williams, Karen, Hickin, H.G., Crackett, Peter H., Dyke, Hazel J., Lockey, Peter M., Wong, Melanie, Devos, René, White, Anne, Belanoff, Joseph K.

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Quinazoline and benzimidazole MCH-1R antagonists von Arienzo, Rosa, Cramp, Sue, Dyke, Hazel J., Lockey, Peter M., Norman, Dennis, Roach, Alan G., Smith, Phil, Wong, Melanie, Wren, Stephen P.

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Identification and optimisation of a series of substituted 5-pyridin-2-yl-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors von Price, Steve, Bordogna, Walter, Braganza, Ruth, Bull, Richard J., Dyke, Hazel J., Gardan, Sophie, Gill, Matthew, Harris, Neil V., Heald, Robert A., van den Heuvel, Marco, Lockey, Peter M., Lloyd, Julia, Molina, Aranzazu G., Roach, Alan G., Roussel, Fabien, Sutton, Jonathan M., White, Anne B.

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2-Benzenesulfonyl-8a-benzyl-hexahydro-2H-isoquinolin-6-ones as selective glucocorticoid receptor antagonists von Clark, Robin D., Ray, Nicholas C., Blaney, Paul, Crackett, Peter H., Hurley, Christopher, Williams, Karen, Dyke, Hazel J., Clark, David E., Lockey, Peter M., Devos, Rene, Wong, Melanie, White, Anne, Belanoff, Joseph K.

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From virtual to clinical: The discovery of PGN-1531, a novel antagonist of the prostanoid EP sub(4) receptor von Sutton, Jon, Clark, David E, Higgs, Christopher, Groot, Marcel Jde, Harris, Neil V, Taylor, Andrea, Lockey, Peter M, Maubach, Karen, Woodrooffe, Amanda, Davis, Richard J, Coleman, Robert A, Clark, Kenneth L

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New Low-Density Lipoprotein Receptor Upregulators Acting via a Novel Mechanism von Ashton, Michael J, Brown, Thomas J, Fenton, Garry, Halley, Frank, Harper, Mark F, Lockey, Peter M, Porter, Barry, Roach, Alan G, Stuttle, Keith A. J, Vicker, Nigel, Walsh, Roger J. A

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3,17.beta.-dihydroxy-20,21-epoxy-19-norpregna-1,3,5(10)-trienes. Synthesis, rearrangement, cytotoxicity, and estrogen-receptor binding von Gill, Julie C, Lockey, Peter M, Marples, Brian A, Traynor, John R

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Application of virtual screening to the discovery of novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with potential for the treatment of cancer and axonopathies von Clark, David E, Waszkowycz, Bohdan, Wong, Melanie, Lockey, Peter M, Adalbert, Robert, Gilley, Jonathan, Clark, Jonathan, Coleman, Michael P

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New non peptidic C5a receptor antagonists von Astles, Peter C., Brown, Thomas J., Cox, Paul, Halley, Frank, Lockey, Peter M., McCarthy, Clive, McLay, Iain M., Majid, Tahir N., Morley, Andrew D., Porter, Barry, Ratcliffe, Andrew J., Walsh, Roger J.A.

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Comparison of the mitogenic activity of angiotensin II and serotonin on porcine arterial smooth muscle cells von Parrott, David P., Lockey, Peter M., Bright, Colin P.

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Alkylating derivatives of oestrogens as potentially target-selecting cytotoxic agents von Peter M. Lockey

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Synthesis and cytotoxic activity of estrogen α-methylene-δ-lactones von Chagonda, Lameck S, Lockey, Peter M., Marples, Brian A., Traynor, John R.

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European Resuscitation Council Guidelines for Resuscitation 2015: Section 4. Cardiac arrest in special circumstances von Truhlář, Anatolij, Deakin, Charles D, Soar, Jasmeet, Khalifa, Gamal Eldin Abbas, Alfonzo, Annette, Bierens, Joost J L M, Brattebø, Guttorm, Brugger, Hermann, Dunning, Joel, Hunyadi-Antičević, Silvija, Koster, Rudolph W, Lockey, David J, Lott, Carsten, Paal, Peter, Perkins, Gavin D, Sandroni, Claudio, Thies, Karl-Christian, Zideman, David A, Nolan, Jerry P

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