Molecular mechanisms of resistance to first- and second-generation ALK inhibitors in ALK-rearranged lung cancer von Gainor, J, Dardaei, L, Yoda, S, Friboulet, L, Leischler, I, Katayama, R, Dagogo-Jack, I, Gadgeel, S, Schultz, K, Singh, M, Chin, E, Parks, M, Lee, D, DiCecca, R.H, Lockerman, E, Huynh, T, Logan, J, Benes, C.H, Engelman, J.A, Shaw, A

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Variation in Mechanisms of Acquired Resistance Among EGFR-Mutant NSCLC Patients With More Than 1 Postresistant Biopsy von Piotrowska, Z, Niederst, M.J, Mino-Kenudson, M, Morales-Oyarvide, V, Fulton, L, Lockerman, E, Howe, E, Gainor, J.F, Fidias, P, Heist, R.S, Shaw, A.T, Engelman, J.A, Sequist, L.V

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The Influence of Affect on 2D Pattern Perception von Fowler, M. L., Lockerman, E., Li, A.

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421 - Molecular mechanisms of resistance to first- and second-generation ALK inhibitors in ALK-rearranged lung cancer von Gainor, J., Dardaei, L., Yoda, S., Friboulet, L., Leischler, I., Katayama, R., Dagogo-Jack, I., Gadgeel, S., Schultz, K., Singh, M., Chin, E., Parks, M., Lee, D., DiCecca, R.H., Lockerman, E., Huynh, T., Logan, J., Benes, C.H., Engelman, J.A., Shaw, A.

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Variation in Mechanisms of Acquired Resistance Among EGFR-Mutant NSCLC Patients With More Than 1 Postresistant Biopsy: Metastatic Non-Small Cell Lung Cancer von Piotrowska, Z., Niederst, M.J., Mino-Kenudson, M., Morales-Oyarvide, V., Fulton, L., Lockerman, E., Howe, E., Gainor, J.F., Fidias, P., Heist, R.S., Shaw, A.T., Engelman, J.A., Sequist, L.V.

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Abstract S4-04: Overcoming resistance to PI3K inhibitors in PIK3CA mutant breast cancer using CDK4/6 inhibition: Results from a combinatorial drug screen von Vora, SR, Kim, N, Costa, C, Lockerman, EL, Li, X, Chen, Y, Cao, A, Pinzon-Ortiz, M, Liu, M, Kim, S, Schlegel, R, Huang, A, Engelman, JA

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Silicone rubber distal ulnar replacement arthroplasty von Sagerman, S.D., Seiler, J.G., Fleming, L.L., Lockerman, E.

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The Allelic Context of the C797S Mutation Acquired upon Treatment with Third-Generation EGFR Inhibitors Impacts Sensitivity to Subsequent Treatment Strategies von Niederst, Matthew J, Hu, Haichuan, Mulvey, Hillary E, Lockerman, Elizabeth L, Garcia, Angel R, Piotrowska, Zofia, Sequist, Lecia V, Engelman, Jeffrey A

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RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer von Niederst, Matthew J., Sequist, Lecia V., Poirier, John T., Mermel, Craig H., Lockerman, Elizabeth L., Garcia, Angel R., Katayama, Ryohei, Costa, Carlotta, Ross, Kenneth N., Moran, Teresa, Howe, Emily, Fulton, Linnea E., Mulvey, Hillary E., Bernardo, Lindsay A., Mohamoud, Farhiya, Miyoshi, Norikatsu, VanderLaan, Paul A., Costa, Daniel B., Jänne, Pasi A., Borger, Darrell R., Ramaswamy, Sridhar, Shioda, Toshi, Iafrate, Anthony J., Getz, Gad, Rudin, Charles M., Mino-Kenudson, Mari, Engelman, Jeffrey A.

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Patient-derived models of acquired resistance can identify effective drug combinations for cancer von Crystal, Adam S., Shaw, Alice T., Sequist, Lecia V., Friboulet, Luc, Niederst, Matthew J., Lockerman, Elizabeth L., Frias, Rosa L., Gainor, Justin F., Amzallag, Arnaud, Greninger, Patricia, Lee, Dana, Kalsy, Anuj, Gomez-Caraballo, Maria, Elamine, Leila, Howe, Emily, Hur, Wooyoung, Lifshits, Eugene, Robinson, Hayley E., Katayama, Ryohei, Faber, Anthony C., Awad, Mark M., Ramaswamy, Sridhar, Mino-Kenudson, Mari, Iafrate, A. John, Benes, Cyril H., Engelman, Jeffrey A.

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Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations von Ahronian, Leanne G, Sennott, Erin M, Van Allen, Eliezer M, Wagle, Nikhil, Kwak, Eunice L, Faris, Jason E, Godfrey, Jason T, Nishimura, Koki, Lynch, Kerry D, Mermel, Craig H, Lockerman, Elizabeth L, Kalsy, Anuj, Gurski, Jr, Joseph M, Bahl, Samira, Anderka, Kristin, Green, Lisa M, Lennon, Niall J, Huynh, Tiffany G, Mino-Kenudson, Mari, Getz, Gad, Dias-Santagata, Dora, Iafrate, A John, Engelman, Jeffrey A, Garraway, Levi A, Corcoran, Ryan B

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Dural arteriovenous fistulas without cortical venous drainage: presentation, treatment, and outcomes von Samaniego, Edgar A, Roa, Jorge A, Hayakawa, Minako, Chen, Ching-Jen, Sheehan, Jason P, Kim, Louis J, Abecassis, Isaac Josh, Levitt, Michael R, Guniganti, Ridhima, Kansagra, Akash P, Lanzino, Giuseppe, Giordan, Enrico, Brinjikji, Waleed, Bulters, Diederik, Durnford, Andrew, Fox, W Christopher, Polifka, Adam J, Gross, Bradley A, Amin-Hanjani, Sepideh, Alaraj, Ali, Kwasnicki, Amanda, Starke, Robert M, Sur, Samir, van Dijk, J Marc C, Potgieser, Adriaan R E, Satomi, Junichiro, Tada, Yoshiteru, Abla, Adib, Winkler, Ethan, Du, Rose, Lai, Pui Man Rosalind, Zipfel, Gregory J, Derdeyn, Colin P

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Intervention for unruptured high-grade intracranial dural arteriovenous fistulas: a multicenter study von Chen, Ching-Jen, Buell, Thomas J, Ding, Dale, Guniganti, Ridhima, Kansagra, Akash P, Lanzino, Giuseppe, Giordan, Enrico, Kim, Louis J, Levitt, Michael R, Abecassis, Isaac Josh, Bulters, Diederik, Durnford, Andrew, Fox, W Christopher, Polifka, Adam J, Gross, Bradley A, Hayakawa, Minako, Derdeyn, Colin P, Samaniego, Edgar A, Amin-Hanjani, Sepideh, Alaraj, Ali, Kwasnicki, Amanda, van Dijk, J Marc C, Potgieser, Adriaan R E, Starke, Robert M, Sur, Samir, Satomi, Junichiro, Tada, Yoshiteru, Abla, Adib A, Winkler, Ethan A, Du, Rose, Lai, Pui Man Rosalind, Zipfel, Gregory J, Sheehan, Jason P

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Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM von Song, Kyung-A, Niederst, Matthew J, Lochmann, Timothy L, Hata, Aaron N, Kitai, Hidenori, Ham, Jungoh, Floros, Konstantinos V, Hicks, Mark A, Hu, Haichuan, Mulvey, Hillary E, Drier, Yotam, Heisey, Daniel A R, Hughes, Mark T, Patel, Neha U, Lockerman, Elizabeth L, Garcia, Angel, Gillepsie, Shawn, Archibald, Hannah L, Gomez-Caraballo, Maria, Nulton, Tara J, Windle, Brad E, Piotrowska, Zofia, Sahingur, Sinem E, Taylor, Shirley M, Dozmorov, Mikhail, Sequist, Lecia V, Bernstein, Bradley, Ebi, Hiromichi, Engelman, Jeffrey A, Faber, Anthony C

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Recurrence after cure in cranial dural arteriovenous fistulas: a collaborative effort by the Consortium for Dural Arteriovenous Fistula Outcomes Research (CONDOR) von Abecassis, Isaac Josh, Meyer, R Michael, Levitt, Michael R, Sheehan, Jason P, Chen, Ching-Jen, Gross, Bradley A, Smith, Jessica, Fox, W Christopher, Giordan, Enrico, Lanzino, Giuseppe, Starke, Robert M, Sur, Samir, Potgieser, Adriaan R E, van Dijk, J Marc C, Durnford, Andrew, Bulters, Diederik, Satomi, Junichiro, Tada, Yoshiteru, Kwasnicki, Amanda, Amin-Hanjani, Sepideh, Alaraj, Ali, Samaniego, Edgar A, Hayakawa, Minako, Derdeyn, Colin P, Winkler, Ethan, Abla, Adib, Lai, Pui Man Rosalind, Du, Rose, Guniganti, Ridhima, Kansagra, Akash P, Zipfel, Gregory J, Kim, Louis J

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Consortium for Dural Arteriovenous Fistula Outcomes Research (CONDOR): rationale, design, and initial characterization of patient cohort von Guniganti, Ridhima, Giordan, Enrico, Chen, Ching-Jen, Abecassis, Isaac Josh, Levitt, Michael R, Durnford, Andrew, Smith, Jessica, Samaniego, Edgar A, Derdeyn, Colin P, Kwasnicki, Amanda, Alaraj, Ali, Potgieser, Adriaan R E, Sur, Samir, Chen, Stephanie H, Tada, Yoshiteru, Winkler, Ethan, Phelps, Ryan R L, Lai, Pui Man Rosalind, Du, Rose, Abla, Adib, Satomi, Junichiro, Starke, Robert M, van Dijk, J Marc C, Amin-Hanjani, Sepideh, Hayakawa, Minako, Gross, Bradley A, Fox, W Christopher, Bulters, Diederik, Kim, Louis J, Sheehan, Jason, Lanzino, Giuseppe, Piccirillo, Jay F, Kansagra, Akash P, Zipfel, Gregory J

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Risk of Early Versus Later Rebleeding From Dural Arteriovenous Fistulas With Cortical Venous Drainage von Durnford, Andrew J., Akarca, Danyal, Culliford, David, Millar, John, Guniganti, Ridhima, Giordan, Enrico, Brinjikji, Waleed, Chen, Ching-Jen, Abecassis, Isaac Josh, Levitt, Michael, Polifka, Adam J., Derdeyn, Colin P., Samaniego, Edgar A., Kwasnicki, Amanda, Alaraj, Ali, Potgieser, Adriaan R.E., Chen, Stephanie, Tada, Yoshiteru, Phelps, Ryan, Abla, Adib, Satomi, Junichiro, Starke, Robert M., van Dijk, J. Marc C., Amin-Hanjani, Sepideh, Hayakawa, Minako, Gross, Bradley, Fox, W. Christopher, Kim, Louis, Sheehan, Jason, Lanzino, Giuseppe, Kansagra, Akash P., Du, Rose, Lai, Rosalind, Zipfel, Gregory J., Bulters, Diederik O.

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Assessing the rate, natural history, and treatment trends of intracranial aneurysms in patients with intracranial dural arteriovenous fistulas: a Consortium for Dural Arteriovenous... von Abecassis, Isaac Josh, Meyer, R Michael, Levitt, Michael R, Sheehan, Jason P, Chen, Ching-Jen, Gross, Bradley A, Lockerman, Ashley, Fox, W Christopher, Brinjikji, Waleed, Lanzino, Giuseppe, Starke, Robert M, Chen, Stephanie H, Potgieser, Adriaan R E, van Dijk, J Marc C, Durnford, Andrew, Bulters, Diederik, Satomi, Junichiro, Tada, Yoshiteru, Kwasnicki, Amanda, Amin-Hanjani, Sepideh, Alaraj, Ali, Samaniego, Edgar A, Hayakawa, Minako, Derdeyn, Colin P, Winkler, Ethan, Abla, Adib, Lai, Pui Man Rosalind, Du, Rose, Guniganti, Ridhima, Kansagra, Akash P, Zipfel, Gregory J, Kim, Louis J

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Focused Helium Ion Beam Nanomachining of Thin Membranes vs. Bulk Substrates von Mutunga, E.M., Lockerman, S., Tan, S., Livengood, R., Vladár, A.E., Klein, K.L.

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Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition von Hata, Aaron N, Niederst, Matthew J, Archibald, Hannah L, Gomez-Caraballo, Maria, Siddiqui, Faria M, Mulvey, Hillary E, Maruvka, Yosef E, Ji, Fei, Bhang, Hyo-eun C, Radhakrishna, Viveksagar Krishnamurthy, Siravegna, Giulia, Hu, Haichuan, Raoof, Sana, Lockerman, Elizabeth, Kalsy, Anuj, Lee, Dana, Keating, Celina L, Ruddy, David A, Damon, Leah J, Crystal, Adam S, Costa, Carlotta, Piotrowska, Zofia, Bardelli, Alberto, Iafrate, Anthony J, Sadreyev, Ruslan I, Stegmeier, Frank, Getz, Gad, Sequist, Lecia V, Faber, Anthony C, Engelman, Jeffrey A

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