The omega‐3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC‐26 colorectal cancer cell liver metastasis via inhibition of PGE2‐dependent cell motility von Hawcroft, G, Volpato, M, Marston, G, Ingram, N, Perry, SL, Cockbain, AJ, Race, AD, Munarini, A, Belluzzi, A, Loadman, PM, Coletta, PL, Hull, MA

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Plasma and rectal mucosal oxylipin levels during aspirin and eicosapentaenoic acid treatment in the seAFOod polyp prevention trial von Fuller, H., Race, A.D., Fenton, H., Burke, L., Downing, A., Williams, E.A., Rees, C.J., Brown, L.C., Loadman, P.M., Hull, M.A.

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Cellular Uptake and Efflux of Palbociclib In Vitro in Single Cell and Spheroid Models von Jove, M, Spencer, J A, Hubbard, M E, Holden, E C, O'Dea, R D, Brook, B S, Phillips, R M, Smye, S W, Loadman, P M, Twelves, C J

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Mathematical and computational models of drug transport in tumours von Groh, C. M., Hubbard, M. E., Jones, P. F., Loadman, P. M., Periasamy, N., Sleeman, B. D., Smye, S. W., Twelves, C. J., Phillips, R. M.

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The use of pharmacokinetic and pharmacodynamic end points to determine the dose of AQ4N, a novel hypoxic cell cytotoxin, given with fractionated radiotherapy in a phase I study von Steward, WP, Middleton, M, Benghiat, A, Loadman, PM, Hayward, C, Waller, S, Ford, S, Halbert, G, Patterson, LH, Talbot, D

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Drug delivery in a tumour cord model: a computational simulation von Hubbard, M. E., Jove, M., Loadman, P. M., Phillips, R. M., Twelves, C. J., Smye, S. W.

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Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: Correlation of MMP-14 mRNA expression and... von Atkinson, J.M, Pennington, C.J, Martin, S.W, Anikin, V.A, Mearns, A.J, Loadman, P.M, Edwards, D.R, Gill, J.H

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Evaluation of the safety of C-1311 (SYMADEX) administered in a phase 1 dose escalation trial as a weekly infusion for 3 consecutive weeks in patients with advanced solid tumours von Isambert, N, Campone, M, Bourbouloux, E, Drouin, M, Major, A, Yin, W, Loadman, P, Capizzi, R, Grieshaber, C, Fumoleau, P

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The omega‐3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC‐26 colorectal cancer cell liver metastasis via inhibition of PGE 2 ‐dependent cell motility von Hawcroft, G, Volpato, M, Marston, G, Ingram, N, Perry, SL, Cockbain, AJ, Race, AD, Munarini, A, Belluzzi, A, Loadman, PM, Coletta, PL, Hull, MA

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5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent: phase I clinical and pharmacokinetic study von Rustin, G J S, Bradley, C, Galbraith, S, Stratford, M, Loadman, P, Waller, S, Bellenger, K, Gumbrell, L, Folkes, L, Halbert, G

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A mathematical model of doxorubicin penetration through multicellular layers von Evans, C.J., Phillips, R.M., Jones, P.F., Loadman, P.M., Sleeman, B.D., Twelves, C.J., Smye, S.W.

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Evaluation of a novel in vitro assay for assessing drug penetration into avascular regions of tumours von PHILLIPS, R. M, LOADMAN, P. M, CRONIN, B. P

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646P A phase I trial of AVA6000, a fibroblast activation protein (FAP)-released, tumor microenvironment (TME)-targeted doxorubicin peptide drug conjugate in patients with FAP-posit... von Twelves, C.J., Banerji, U., Tap, W.D., Cook, N., Evans, T.R.J., Plummer, R., Anthoney, A., Plummer, C., Dawson, R., Loadman, P., Lahu, G., Jones, H., Kinnersley, N., Edwards, R., Gordon, G., Cranmer, L.D.

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Pharmacological approach towards the development of indolequinone bioreductive drugs based on the clinically inactive agent EO9 von Loadman, P M, Bibby, M C, Phillips, R M

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Pharmacokinetics of PK1 and Doxorubicin in Experimental Colon Tumor Models with Differing Responses to PK1 von LOADMAN, P. M, BIBBY, M. C, DOUBLE, J. A, AL-SHAKHAA, W. M, DUNCAN, R

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Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice von Loadman, Paul M, Phillips, Roger M, Lim, Lissa E, Bibby, Mike C

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Separation methods for anthraquinone related anti-cancer drugs von Loadman, Paul M, Calabrese, Christopher R

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Angiogenesis in the hollow fiber tumor model influences drug delivery to tumor cells : Implications for anticancer drug screening programs von PHILLIPS, R. M, PEARCE, J, LOADMAN, P. M, BIBBY, M. C, COOPER, P. A, SWAINE, D. J, DOUBLE, J. A

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5-Fluorouracil (5FU) intratumoural pharmacokinetics: Rapid uptake in cells and in spheroids (SPH) von Jove, M., Loadman, P., Wicks, J., Spencer, J., Race, A., Salazar, R., Twelves, C.J.

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427 The development and evaluation of an experimental model for assessing convective fluid flow through multicell layers von Phillips, R, Makeen, H, Periasamy, N, Loadman, P, Smye, S, Sleeman, B, Jones, P, Evans, C, Twelves, C

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