The impact of opioid-induced constipation among chronic pain patients with sufficient laxative use von LoCasale, R. J., Datto, C. J., Margolis, M. K., Tack, J., Coyne, K. S.

Volltext

Burden of cardio‐renal‐metabolic conditions in adults with type 2 diabetes within the Diabetes Collaborative Registry von Arnold, Suzanne V., Kosiborod, Mikhail, Wang, Jingyan, Fenici, Peter, Gannedahl, Goran, LoCasale, Robert J.

Volltext

Opioid-induced constipation in patients with chronic noncancer pain in the USA, Canada, Germany, and the UK: descriptive analysis of baseline patient-reported outcomes and retrospe... von Coyne, Karin S, LoCasale, Robert J, Datto, Catherine J, Sexton, Chris C, Yeomans, Karen, Tack, Jan

Volltext

The Burden of Opioid-Induced Constipation: Discordance Between Patient and Health Care Provider Reports von LoCasale, Robert J., Datto, Catherine, Wilson, Hilary, Yeomans, Karen, Coyne, Karin S.

Volltext

Human sperm displays rapid responses to diet von Nätt, Daniel, Kugelberg, Unn, Casas, Eduard, Nedstrand, Elizabeth, Zalavary, Stefan, Henriksson, Pontus, Nijm, Carola, Jäderquist, Julia, Sandborg, Johanna, Flinke, Eva, Ramesh, Rashmi, Örkenby, Lovisa, Appelkvist, Filip, Lingg, Thomas, Guzzi, Nicola, Bellodi, Cristian, Löf, Marie, Vavouri, Tanya, Öst, Anita

Volltext

Towards precision medicine in diabetes? A critical review of glucotypes von Hulman, Adam, Foreman, Yuri D, Brouwers, Martijn C G J, Kroon, Abraham A, Reesink, Koen D, Dagnelie, Pieter C, van der Kallen, Carla J H, Greevenbroek, Marleen M J van, Færch, Kristine, Vistisen, Dorte, Jørgensen, Marit E, Stehouwer, Coen D A, Witte, Daniel R

Volltext

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism von Johnson, Marc O., Wolf, Melissa M., Madden, Matthew Z., Andrejeva, Gabriela, Sugiura, Ayaka, Contreras, Diana C., Maseda, Damian, Liberti, Maria V., Paz, Katelyn, Kishton, Rigel J., Johnson, Matthew E., de Cubas, Aguirre A., Wu, Pingsheng, Li, Gongbo, Zhang, Yongliang, Newcomb, Dawn C., Wells, Andrew D., Restifo, Nicholas P., Rathmell, W. Kimryn, Locasale, Jason W., Davila, Marco L., Blazar, Bruce R., Rathmell, Jeffrey C.

Volltext

The molecular and metabolic program by which white adipocytes adapt to cool physiologic temperatures von Mori, Hiroyuki, Dugan, Colleen E, Nishii, Akira, Benchamana, Ameena, Li, Ziru, Cadenhead, 4th, Thomas S, Das, Arun K, Evans, Charles R, Overmyer, Katherine A, Romanelli, Steven M, Peterson, Sydney K, Bagchi, Devika P, Corsa, Callie A, Hardij, Julie, Learman, Brian S, El Azzouny, Mahmoud, Coon, Joshua J, Inoki, Ken, MacDougald, Ormond A

Volltext

A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity von Cao, Jennifer Yinuo, Poddar, Aunoy, Magtanong, Leslie, Lumb, Jennifer H., Mileur, Trevor R., Reid, Michael A., Dovey, Cole M., Wang, Jin, Locasale, Jason W., Stone, Everett, Cole, Susan P.C., Carette, Jan E., Dixon, Scott J.

Volltext

AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival von Kishton, Rigel J., Barnes, Carson E., Nichols, Amanda G., Cohen, Sivan, Gerriets, Valerie A., Siska, Peter J., Macintyre, Andrew N., Goraksha-Hicks, Pankuri, de Cubas, Aguirre A., Liu, Tingyu, Warmoes, Marc O., Abel, E. Dale, Yeoh, Allen Eng Juh, Gershon, Timothy R., Rathmell, W. Kimryn, Richards, Kristy L., Locasale, Jason W., Rathmell, Jeffrey C.

Volltext

Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells von Vander Heiden, Matthew G, Locasale, Jason W, Swanson, Kenneth D, Sharfi, Hadar, Heffron, Greg J, Amador-Noguez, Daniel, Christofk, Heather R, Wagner, Gerhard, Rabinowitz, Joshua D, Asara, John M, Cantley, Lewis C

Volltext

A roadmap for interpreting (13)C metabolite labeling patterns from cells von Buescher, Joerg M, Antoniewicz, Maciek R, Boros, Laszlo G, Burgess, Shawn C, Brunengraber, Henri, Clish, Clary B, DeBerardinis, Ralph J, Feron, Olivier, Frezza, Christian, Ghesquiere, Bart, Gottlieb, Eyal, Hiller, Karsten, Jones, Russell G, Kamphorst, Jurre J, Kibbey, Richard G, Kimmelman, Alec C, Locasale, Jason W, Lunt, Sophia Y, Maddocks, Oliver D K, Malloy, Craig, Metallo, Christian M, Meuillet, Emmanuelle J, Munger, Joshua, Nöh, Katharina, Rabinowitz, Joshua D, Ralser, Markus, Sauer, Uwe, Stephanopoulos, Gregory, St-Pierre, Julie, Tennant, Daniel A, Wittmann, Christoph, Vander Heiden, Matthew G, Vazquez, Alexei, Vousden, Karen, Young, Jamey D, Zamboni, Nicola, Fendt, Sarah-Maria

Volltext

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis von Locasale, Jason W, Cantley, Lewis C, Vander Heiden, Matthew G, Grassian, Alexandra R, Melman, Tamar, Lyssiotis, Costas A, Mattaini, Katherine R, Bass, Adam J, Heffron, Gregory, Metallo, Christian M, Muranen, Taru, Sharfi, Hadar, Sasaki, Atsuo T, Anastasiou, Dimitrios, Mullarky, Edouard, Vokes, Natalie I, Sasaki, Mika, Beroukhim, Rameen, Stephanopoulos, Gregory, Ligon, Azra H, Meyerson, Matthew, Richardson, Andrea L, Chin, Lynda, Wagner, Gerhard, Asara, John M, Brugge, Joan S

Volltext

Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence von Singleton, Katherine R., Crawford, Lorin, Tsui, Elizabeth, Manchester, Haley E., Maertens, Ophelia, Liu, Xiaojing, Liberti, Maria V., Magpusao, Anniefer N., Stein, Elizabeth M., Tingley, Jennifer P., Frederick, Dennie T., Boland, Genevieve M., Flaherty, Keith T., McCall, Shannon J., Krepler, Clemens, Sproesser, Katrin, Herlyn, Meenhard, Adams, Drew J., Locasale, Jason W., Cichowski, Karen, Mukherjee, Sayan, Wood, Kris C.

Volltext

Myeloid Slc2a1 -Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1 von Freemerman, Alex J, Zhao, Liyang, Pingili, Ajeeth K, Teng, Bin, Cozzo, Alyssa J, Fuller, Ashley M, Johnson, Amy R, Milner, J Justin, Lim, Maili F, Galanko, Joseph A, Beck, Melinda A, Bear, James E, Rotty, Jeremy D, Bezavada, Lavanya, Smallwood, Heather S, Puchowicz, Michelle A, Liu, Juan, Locasale, Jason W, Lee, Douglas P, Bennett, Brian J, Abel, E Dale, Rathmell, Jeff C, Makowski, Liza

Volltext

MNK2 deficiency potentiates β-cell regeneration via translational regulation von Karampelias, Christos, Watt, Kathleen, Mattsson, Charlotte L., Ruiz, Ángel Fernández, Rezanejad, Habib, Mi, Jiarui, Liu, Xiaojing, Chu, Lianhe, Locasale, Jason W., Korbutt, Gregory S., Rovira, Meritxell, Larsson, Ola, Andersson, Olov

Volltext

Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain von Chen, Jinyu, Lee, Ho-Jeong, Wu, Xuefeng, Huo, Lei, Kim, Sun-Jin, Xu, Lei, Wang, Yan, He, Junqing, Bollu, Lakshmi R, Gao, Guang, Su, Fei, Briggs, James, Liu, Xiaojing, Melman, Tamar, Asara, John M, Fidler, Isaiah J, Cantley, Lewis C, Locasale, Jason W, Weihua, Zhang

Volltext

The role of prediction modeling in propensity score estimation: an evaluation of logistic regression, bCART, and the covariate-balancing propensity score von Wyss, Richard, Ellis, Alan R, Brookhart, M Alan, Girman, Cynthia J, Jonsson Funk, Michele, LoCasale, Robert, Stürmer, Til

Volltext

Metabolic adaptation to tyrosine kinase inhibition in leukemia stem cells von Qiu, Shaowei, Sheth, Vipul, Yan, Chengcheng, Liu, Juan, Chacko, Balu K, Li, Hui, Crossman, David K, Fortmann, Seth D, Aryal, Sajesan, Rennhack, Ashley, Grant, Maria B, Welner, Robert S, Paterson, Andrew J, Wende, Adam R, Darley-Usmar, Victor M, Lu, Rui, Locasale, Jason W, Bhatia, Ravi

Volltext

Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers von Liao, Chengheng, Glodowski, Cherise Ryan, Fan, Cheng, Liu, Juan, Mott, Kevin R, Kaushik, Akash, Vu, Hieu, Locasale, Jason W, McBrayer, Samuel K, DeBerardinis, Ralph J, Perou, Charles M, Zhang, Qing

Volltext