Understanding and Modeling Metastasis Biology to Improve Therapeutic Strategies for Combating Osteosarcoma Progression von Fan, Timothy M., Roberts, Ryan D., Lizardo, Michael M.

Volltext

Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression von Heinecke, Julie L., Ridnour, Lisa A., Cheng, Robert Y. S., Switzer, Christopher H., Lizardo, Michael M., Khanna, Chand, Glynn, Sharon A., Hussain, S. Perwez, Young, Howard A., Ambs, Stefan, Wink, David A.

Volltext

Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group von Roberts, Ryan D., Lizardo, Michael M., Reed, Damon R., Hingorani, Pooja, Glover, Jason, Allen‐Rhoades, Wendy, Fan, Timothy, Khanna, Chand, Sweet‐Cordero, E. Alejandro, Cash, Thomas, Bishop, Michael W., Hegde, Meenakshi, Sertil, Aparna R., Koelsche, Christian, Mirabello, Lisa, Malkin, David, Sorensen, Poul H., Meltzer, Paul S., Janeway, Katherine A., Gorlick, Richard, Crompton, Brian D.

Volltext

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence von Morrow, James J, Bayles, Ian, Funnell, Alister P W, Miller, Tyler E, Saiakhova, Alina, Lizardo, Michael M, Bartels, Cynthia F, Kapteijn, Maaike Y, Hung, Stevephen, Mendoza, Arnulfo, Dhillon, Gursimran, Chee, Daniel R, Myers, Jay T, Allen, Frederick, Gambarotti, Marco, Righi, Alberto, DiFeo, Analisa, Rubin, Brian P, Huang, Alex Y, Meltzer, Paul S, Helman, Lee J, Picci, Piero, Versteeg, Henri H, Stamatoyannopoulos, John A, Khanna, Chand, Scacheri, Peter C

Volltext

A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma von Ramos, Louise, Truong, Sarah, Zhai, Beibei, Joshi, Jay, Ghaidi, Fariba, Lizardo, Michael M., Shyp, Taras, Kung, Sonia H.Y., Rezakhanlou, Alireza M., Oo, Htoo Zarni, Adomat, Hans, Le Bihan, Stephane, Collins, Colin, Bacha, Jeffrey, Brown, Dennis, Langlands, John, Shen, Wang, Lallous, Nada, Sorensen, Poul H., Daugaard, Mads

Volltext

Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma von Zhang, Hai-Feng, Hughes, Christopher S., Li, Wei, He, Jian-Zhong, Surdez, Didier, El-Naggar, Amal M., Cheng, Hongwei, Prudova, Anna, Delaidelli, Alberto, Negri, Gian Luca, Li, Xiaojun, Orum-Madsen, Maj Sofie, Lizardo, Michael M., Oo, Htoo Zarni, Colborne, Shane, Shyp, Taras, Scopim-Ribeiro, Renata, Hammond, Colin A., Dhez, Anne-Chloe, Langman, Sofya, Lim, Jonathan K. M., Kung, Sonia H. Y., Li, Amy, Steino, Anne, Daugaard, Mads, Parker, Seth J., Geltink, Ramon I. Klein, Orentas, Rimas J., Xu, Li-Yan, Morin, Gregg B., Delattre, Olivier, Dimitrov, Dimiter S., Sorensen, Poul H.

Volltext

Characterization of the metastatic phenotype of a panel of established osteosarcoma cells von Ren, Ling, Mendoza, Arnulfo, Zhu, Jack, Briggs, Joseph W, Halsey, Charles, Hong, Ellen S, Burkett, Sandra S, Morrow, James, Lizardo, Michael M, Osborne, Tanasa, Li, Samuel Q, Luu, Hue H, Meltzer, Paul, Khanna, Chand

Volltext

Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression von Lizardo, Michael M, Morrow, James J, Miller, Tyler E, Hong, Ellen S, Ren, Ling, Mendoza, Arnulfo, Halsey, Charles H, Scacheri, Peter C, Helman, Lee J, Khanna, Chand

Volltext

Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation von Ridnour, Lisa A, Barasch, Kimberly M, Windhausen, Alisha N, Dorsey, Tiffany H, Lizardo, Michael M, Yfantis, Harris G, Lee, Dong H, Switzer, Christopher H, Cheng, Robert Y S, Heinecke, Julie L, Brueggemann, Ernst, Hines, Harry B, Khanna, Chand, Glynn, Sharon A, Ambs, Stefan, Wink, David A

Volltext

The HACE1 E3 ligase mediates RAC1‐dependent control of mTOR signaling complexes von Turgu, Busra, El‐Naggar, Amal, Kogler, Melanie, Tortola, Luigi, Zhang, Hai‐Feng, Hassan, Mariam, Lizardo, Michael M, Kung, Sonia HY, Lam, Wan, Penninger, Josef M, Sorensen, Poul H

Volltext

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay von Lizardo, Michael M, Sorensen, Poul H

Volltext

NSG Mice Facilitate ex vivo Characterization of Ewing Sarcoma Lung Metastasis Using the PuMA Model von Scopim-Ribeiro, Renata, Lizardo, Michael M., Zhang, Hai-Feng, Dhez, Anne-Chloe, Hughes, Chistopher S., Sorensen, Poul H.

Volltext

mTOR Inhibition Mitigates Enhanced mRNA Translation Associated with the Metastatic Phenotype of Osteosarcoma Cells In Vivo von Morrow, James J, Mendoza, Arnulfo, Koyen, Allyson, Lizardo, Michael M, Ren, Ling, Waybright, Timothy J, Hansen, Ryan J, Gustafson, Daniel L, Zhou, Ming, Fan, Timothy M, Scacheri, Peter C, Khanna, Chand

Volltext

Dysregulation of Ezrin Phosphorylation Prevents Metastasis and Alters Cellular Metabolism in Osteosarcoma von LING REN, HONG, Sung-Hyeok, KHAN, Javed, KHANNA, Chand, CHEN, Qing-Rong, BRIGGS, Joseph, CASSAVAUGH, Jessica, SRINIVASAN, Satish, LIZARDO, Michael M, MENDOZA, Arnulfo, XIA, Ashley Y, AVADHANI, Narayan

Volltext

Imaging the impact of chemically inducible proteins on cellular dynamics in vivo von Leong, Hon S, Lizardo, Michael M, Ablack, Amber, McPherson, Victor A, Wandless, Thomas J, Chambers, Ann F, Lewis, John D

Volltext

A MYCN-independent mechanism mediating secretome reprogramming and metastasis in MYCN -amplified neuroblastoma von Zhang, Hai-Feng, Delaidelli, Alberto, Javed, Sumreen, Turgu, Busra, Morrison, Taylor, Hughes, Christopher S, Yang, Xiaqiu, Pachva, Manideep, Lizardo, Michael M, Singh, Gurdeep, Hoffmann, Jennifer, Huang, Yue Zhou, Patel, Khushbu, Shraim, Rawan, Kung, Sonia H Y, Morin, Gregg B, Aparicio, Samuel, Martinez, Daniel, Maris, John M, Bosse, Kristopher R, Williams, Karla C, Sorensen, Poul H

Volltext

Abstract B10: Modulation of mRNA translation regulation in highly metastatic ssteosarcoma cells increases their sensitivity to redox stress von Lizardo, Michael M., Sorensen, Poul

Volltext

Abstract B55: MYCN promotes m6a-dependent translation of eEF2K mRNA during adaptation to ER stress von Vislovukh, Andrii, Hughes, Cristopher, Lizardo, Michael, Sorensen, Poul H.

Volltext

Abstract A19: Immunologic dysfunctions of NSG mice confer higher engraftment levels of xenograft Ewing sarcoma metastasis in the PuMA model compared to NOD-SCID mice von Scopim-Ribeiro, Renata, Lizardo, Michael M., Dhez, Anne-Chloe, El-Naggar, Amal M., Sorensen, Poul H.

Volltext

Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis von Webb, Meghan, Emberley, Ethan D, Lizardo, Michael, Alowami, Salem, Qing, Gefei, Alfia'ar, Abdullah, Snell-Curtis, Linda J, Niu, Yulian, Civetta, Alberto, Myal, Yvonne, Shiu, Robert, Murphy, Leigh C, Watson, Peter H

Volltext