Pharmacokinetic/Pharmacodynamic Modeling Identifies SN30000 and SN29751 as Tirapazamine Analogues with Improved Tissue Penetration and Hypoxic Cell Killing in Tumors von HICKS, Kevin O, SIIM, Bronwyn G, DENNY, William A, HAY, Michael P, WILSON, William R, JAISWAL, Jagdish K, PRUIJN, Frederik B, FRASER, Annie M, PATEL, Rita, HOGG, Alison, SARATH LIYANAGE, H. D, JO DORIE, Mary, BROWN, J. Martin

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Drug-DNA adducts as biomarkers for metabolic activation of the nitro-aromatic nitrogen mustard prodrug PR-104A von Stornetta, Alessia, Deng, Kai-Cheng Kieren, Danielli, Sara, Liyanage, H.D. Sarath, Sturla, Shana J., Wilson, William R., Gu, Yongchuan

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The flavoprotein FOXRED2 reductively activates nitro-chloromethylbenzindolines and other hypoxia-targeting prodrugs von Hunter, Francis W., Jaiswal, Jagdish K., Hurley, Daniel G., Liyanage, H.D. Sarath, McManaway, Sarah P., Gu, Yongchuan, Richter, Susan, Wang, Jingli, Tercel, Moana, Print, Cristin G., Wilson, William R., Pruijn, Frederik B.

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Nitro-chloromethylbenzindolines: hypoxia-activated prodrugs of potent adenine N3 DNA minor groove alkylators von Wilson, William R, Stribbling, Stephen M, Pruijn, Frederik B, Syddall, Sophie P, Patterson, Adam V, Liyanage, H D Sarath, Smith, Eileen, Botting, K Jane, Tercel, Moana

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Nitro-chloromethylbenzindolines: hypoxia-activated prodrugs of potent adenine N 3 DNA minor groove alkylators von Wilson, William R., Stribbling, Stephen M., Pruijn, Frederik B., Syddall, Sophie P., Patterson, Adam V., Liyanage, H.D. Sarath, Smith, Eileen, Botting, K. Jane, Tercel, Moana

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