The clinical benefit of mepolizumab replacing omalizumab in uncontrolled severe eosinophilic asthma von Chapman, Kenneth R., Albers, Frank C., Chipps, Bradley, Muñoz, Xavier, Devouassoux, Gilles, Bergna, Miguel, Galkin, Dmitry, Azmi, Jay, Mouneimne, Dalal, Price, Robert G., Liu, Mark C.

Volltext

Stopping versus continuing long-term mepolizumab treatment in severe eosinophilic asthma (COMET study) von Moore, Wendy C, Kornmann, Oliver, Humbert, Marc, Poirier, Claude, Bel, Elisabeth H, Kaneko, Norihiro, Smith, Steven G, Martin, Neil, Gilson, Martyn J, Price, Robert G, Bradford, Eric S, Liu, Mark C

Volltext

From DREAM to REALITI‐A and beyond: Mepolizumab for the treatment of eosinophil‐driven diseases von Pavord, Ian D., Bel, Elisabeth H., Bourdin, Arnaud, Chan, Robert, Han, Joseph K., Keene, Oliver N., Liu, Mark C., Martin, Neil, Papi, Alberto, Roufosse, Florence, Steinfeld, Jonathan, Wechsler, Michael E., Yancey, Steven W.

Volltext

Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease von Pothoven, Kathryn L., PhD, Norton, James E., MSc, Suh, Lydia A., BSc, Carter, Roderick G., BSc, Harris, Kathleen E., BSc, Biyasheva, Assel, PhD, Welch, Kevin, MD, Shintani-Smith, Stephanie, MD, Conley, David B., MD, Liu, Mark C., MD, Kato, Atsushi, PhD, Avila, Pedro C., MD, Hamid, Qutayba, MD, PhD, Grammer, Leslie C., MD, Peters, Anju T., MD, Kern, Robert C., MD, Tan, Bruce K., MD, Schleimer, Robert P., PhD

Volltext

Effect of mepolizumab in severe eosinophilic asthma according to omalizumab eligibility von Humbert, Marc, Albers, Frank C., Bratton, Daniel J., Yancey, Steven W., Liu, Mark C., Hozawa, Soichiro, Llanos, Jean-Pierre, Kwon, Namhee

Volltext

Benefit of switching to mepolizumab from omalizumab in severe eosinophilic asthma based on patient characteristics von Liu, Mark C, Chipps, Bradley, Munoz, Xavier, Devouassoux, Gilles, Bergna, Miguel, Smith, Steven G, Price, Robert G, Galkin, Dmitry V, Azmi, Jay, Mouneimne, Dalal, Albers, Frank C, Chapman, Kenneth R

Volltext

Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease von Pothoven, Kathryn L., MSc, Norton, James E., MSc, Hulse, Kathryn E., PhD, Suh, Lydia A., BSc, Carter, Roderick G., BSc, Rocci, Erin, BSc, Harris, Kathleen E., BSc, Shintani-Smith, Stephanie, MD, Conley, David B., MD, Chandra, Rakesh K., MD, Liu, Mark C., MD, Kato, Atsushi, PhD, Gonsalves, Nirmala, MD, Grammer, Leslie C., MD, Peters, Anju T., MD, Kern, Robert C., MD, Bryce, Paul J., PhD, Tan, Bruce K., MD, MS, Schleimer, Robert P., PhD

Volltext

Impact of baseline clinical asthma characteristics on the response to mepolizumab: a post hoc meta-analysis of two Phase III trials von Lemiere, Catherine, Taillé, Camille, Lee, Jason Kihyuk, Smith, Steven G., Mallett, Stephen, Albers, Frank C., Bradford, Eric S., Yancey, Steven W., Liu, Mark C.

Volltext

Sex differences in M2 polarization, chemokine and IL-4 receptors in monocytes and macrophages from asthmatics von Becerra-Díaz, Mireya, Lerner, Andrew D., Yu, Diana H., Thiboutot, Jeffrey P., Liu, Mark C., Yarmus, Lonny B., Bose, Sonali, Heller, Nicola M.

Volltext

Safety and efficacy of the prostaglandin D2 receptor antagonist AMG 853 in asthmatic patients von Busse, William W., MD, Wenzel, Sally E., MD, Meltzer, Eli O., MD, Kerwin, Edward M., MD, Liu, Mark C., MD, Zhang, Nan, PhD, Chon, Yun, PhD, Budelsky, Alison L., PhD, Lin, Joseph, MD, Lin, Shao-Lee, MD, PhD

Volltext

Asthma outcomes: Pulmonary physiology von Tepper, Robert S., MD, PhD, Wise, Robert S., MD, Covar, Ronina, MD, Irvin, Charles G., PhD, Kercsmar, Carolyn M., MD, MS, Kraft, Monica, MD, Liu, Mark C., MD, O'Connor, George T., MD, MS, Peters, Stephen P., MD, PhD, Sorkness, Ronald, MS, PhD, RPh, Togias, Alkis, MD

Volltext

Effects of omalizumab on basophil and mast cell responses using an intranasal cat allergen challenge von Eckman, John A., MD, Sterba, Patricia M., MS, Kelly, Denise, RN, BSN, Alexander, Val, BS, Liu, Mark C., MD, Bochner, Bruce S., MD, MacGlashan, Donald W., MD, PhD, Saini, Sarbjit S., MD

Volltext

Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma von Ortega, Hector G, Liu, Mark C, Pavord, Ian D, Brusselle, Guy G, FitzGerald, J. Mark, Chetta, Alfredo, Humbert, Marc, Katz, Lynn E, Keene, Oliver N, Yancey, Steven W, Chanez, Pascal

Volltext

Local release of B cell–activating factor of the TNF family after segmental allergen challenge of allergic subjects von Kato, Atsushi, PhD, Xiao, HuiQing, MD, Chustz, Regina T., BS, Liu, Mark C., MD, Schleimer, Robert P., PhD

Volltext

Serum Amyloid A Regulates Granulomatous Inflammation in Sarcoidosis through Toll-like Receptor-2 von Chen, Edward S, Song, Zhimin, Willett, Matthew H, Heine, Shannon, Yung, Rex C, Liu, Mark C, Groshong, Steve D, Zhang, Ying, Tuder, Rubin M, Moller, David R

Volltext

The structural basis of airways hyperresponsiveness in asthma von Brown, Robert H, Pearse, David B, Pyrgos, George, Liu, Mark C, Togias, Alkis, Permutt, Solbert

Volltext

Release of both CCR4-active and CXCR3-active chemokines during human allergic pulmonary late-phase reactions von Bochner, Bruce S, Hudson, Shery A, Xiao, Hui Qing, Liu, Mark C

Volltext

Inflammatory cells in asthma: Mechanisms and implications for therapy von Hamid, Qutayba, Tulic', Meri K., Liu, Mark C., Moqbel, Redwan

Volltext

Role of nasal nitric oxide in the resolution of experimental rhinovirus infection von Sanders, Scherer P, Proud, David, Permutt, Solbert, Siekierski, Edward S, Yachechko, Robin, Liu, Mark C

Volltext

Mepolizumab real-world effectiveness in severe asthma with an eosinophilic phenotype and overlapping severe allergic asthma von Lee, Jason K., Pollard, Stephen J., Liu, Mark C., Schleich, Florence, Pelaia, Girolamo, Almonacid, Carlos, Heaney, Liam G., Chaudhuri, Rekha, Alfonso-Cristancho, Rafael, Zhang, Lingjiao, Maxwell, Aoife, Howarth, Peter

Volltext