N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain von Raikwar, Nandita S, Liu, Kang Z, Thomas, Christie P

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A Recently Evolved Novel Trophoblast-Enriched Secreted Form of fms-Like Tyrosine Kinase-1 Variant Is Up-Regulated in Hypoxia and Preeclampsia von Thomas, Christie P., Andrews, Janet I., Raikwar, Nandita S., Kelley, Elizabeth A., Herse, Florian, Dechend, Ralf, Golos, Thaddeus G., Liu, Kang Z.

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Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist von Raikwar, Nandita S., Liu, Kang Z., Thomas, Christie P.

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Intronic polyadenylation signal sequences and alternate splicing generate human soluble Flt1 variants and regulate the abundance of soluble Flt1 in the placenta von Thomas, Christie P, Andrews, Janet I, Liu, Kang Z

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Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage von Raikwar, Nandita S., Liu, Kang Z., Thomas, Christie P.

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A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in the collecting duct von Raikwar, Nandita S, Liu, Kang Z, Thomas, Christie P

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Alternate processing of Flt1 transcripts is directed by conserved cis-elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation von Thomas, Christie P, Raikwar, Nandita S, Kelley, Elizabeth A, Liu, Kang Z

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Glucocorticoids stimulate human sgk1 gene expression by activation of a GRE in its 5'-flanking region von Itani, Omar A, Liu, Kang Z, Cornish, Kristyn L, Campbell, Jason R, Thomas, Christie P

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Medroxyprogesterone acetate binds the glucocorticoid receptor to stimulate alpha-ENaC and sgk1 expression in renal collecting duct epithelia von Thomas, Christie P, Liu, Kang Z, Vats, Hemender S

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Cycloheximide increases glucocorticoid-stimulated alpha -ENaC mRNA in collecting duct cells by p38 MAPK-dependent pathway von Itani, Omar A, Cornish, Kristyn L, Liu, Kang Z, Thomas, Christie P

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Systemic pseudohypoaldosteronism from deletion of the promoter region of the human Beta epithelial na(+) channel subunit von Thomas, Christie P, Zhou, Jackie, Liu, Kang Z, Mick, Verity E, MacLaughlin, Eithne, Knowles, Michael

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Genomic organization of the 5' end of human beta-ENaC and preliminary characterization of its promoter von Thomas, Christie P, Loftus, Randy W, Liu, Kang Z, Itani, Omar A

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AVP-induced VIT32 gene expression in collecting duct cells occurs via trans-activation of a CRE in the 5'-flanking region of the VIT32 gene von Thomas, Christie P, Loftus, Randy W, Liu, Kang Z

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Gene symbol: SCNN1B. Disease: Pseudohypoaldosteronism, type 1 von Thomas, C P, Zhou, Jackie, Liu, Kang Z, Mick, Verity E, MacLaughlin, Eithne, Knowles, Michael

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Post‐translational cleavage of Flt1 occurs very close to transmembrane domain releasing extracellular N‐terminal fragment which binds to PlGF von Raikwar, Nandita S, Liu, Kang Z, Thomas, Christie P

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A regulated NH 2 -terminal Sgk1 variant with enhanced function is expressed in the collecting duct von Raikwar, Nandita S., Liu, Kang Z., Thomas, Christie P.

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A regulated NH^sub 2^-terminal Sgk1 variant with enhanced function is expressed in the collecting duct von Raikwar, Nandita S, Liu, Kang Z, Thomas, Christie P

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VEGFR‐1/FLT‐1 is induced by protein kinase C and its Ectodomain Cleavage is regulated by glycosylation and metalloproteases von Raikwar, Nandita S, Liu, Kang Z, Thomas, Christie P

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A regulated NH2-terminal Sgkl variant with enhanced function is expressed in the collecting duct von RAIKWAR, Nandita S, LIU, Kang Z, THOMAS, Christie P

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Intronic polyadenylation signal sequences and alternate splicing generate human soluble Fltl variants and regulate the abundance of soluble Flt1 in the placenta von Thomas, Christie P., Andrews, Janet I., Liu, Kang Z.

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