Overcoming Barriers: A Comprehensive Review of Chronic Pain Management and Accessibility Challenges in Rural America von Baker, Maxwell B, Liu, Eileen C, Bully, Micaiah A, Hsieh, Adam, Nozari, Ala, Tuler, Marissa, Binda, Dhanesh D

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De novo mutations in epileptic encephalopathies von Andrew S. Allen1, Samuel F. Berkovic2, Patrick Cossette3, Norman Delanty4, Dennis Dlugos5, Evan E. Eichler6, Michael P. Epstein7, Tracy Glauser8, David B. Goldstein9, Johnson, MR, Ruben Kuzniecky12, Daniel H. Lowenstein13, Yi-Fan Lu9, Maura R. Z.Madou, Anthony G. Marson14, Heather C. Mefford15, Sahar Esmaeeli Nieh16, Terence J. O’Brien17, Ruth Ottman18, Slave´ Petrovski2,9,17, Annapurna Poduri19, Elizabeth K Ruzzo9, Ingrid E. Scheffer20,21, Elliott H. Sherr22 & Christopher J. Yuskaitis23, Bassel Abou-Khalil24, Brian K. Alldredge25, Jocelyn F. Bautista26, Samuel F. Berkovic2, Alex Boro27, Gregory D. Cascino28, Damian Consalvo29, Patricia Crumrine30, Orinn Devinsky31, Dennis Dlugos5, Michael P. Epstein7, Miguel Fiol32, Nathan B. Fountain33, Jacqueline French12, Daniel Friedman12, Eric B. Geller34, Tracy Glauser8, SIMON Glynn35, Sheryl R. Haut36, Jean Hayward37, Sandra L. Helmers38, Sucheta Joshi39, Andres Kanner40, Heidi E. Kirsch13,41, Robert C. Knowlton42, Eric H. Kossoff43, Rachel Kuperman44, Ruben Kuzniecky12, Daniel H. Lowenstein13, Shannon M. McGuire45, Paul V. Motika46, Edward J. Novotny47, Ruth Ottman18, Juliann M. Paolicchi48, Jack Parent49,50, Kristen Park51, Annapurna Poduri19, Ingrid E. Scheffer20,21, Renee A Shellhaas52, Elliott H. Sherr22, Jerry J. Shih53, Rani Singh54, Joseph Sirven55, Michael C Smith40, Joseph Sullivan13, K. Liu Lin Thio56, Anu Venkat5, Eileen P. G. Vining57, GretchenK. VonAllmen58, Judith L.Weisenberg59, Peter Widdess-Walsh34&Melodie R.Winawer

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High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue von Liu, Yang, Yang, Mingyu, Deng, Yanxiang, Su, Graham, Enninful, Archibald, Guo, Cindy C., Tebaldi, Toma, Zhang, Di, Kim, Dongjoo, Bai, Zhiliang, Norris, Eileen, Pan, Alisia, Li, Jiatong, Xiao, Yang, Halene, Stephanie, Fan, Rong

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CoralTemp and the Coral Reef Watch Coral Bleaching Heat Stress Product Suite Version 3.1 von Skirving, William, Marsh, Benjamin, De La Cour, Jacqueline, Liu, Gang, Harris, Andy, Maturi, Eileen, Geiger, Erick, Eakin, C. Mark

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Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women von Landovitz, Raphael J, Donnell, Deborah, Clement, Meredith E, Hanscom, Brett, Cottle, Leslie, Coelho, Lara, Cabello, Robinson, Chariyalertsak, Suwat, Dunne, Eileen F, Frank, Ian, Gallardo-Cartagena, Jorge A, Gaur, Aditya H, Gonzales, Pedro, Tran, Ha V, Hinojosa, Juan C, Kallas, Esper G, Kelley, Colleen F, Losso, Marcelo H, Madruga, J. Valdez, Middelkoop, Keren, Phanuphak, Nittaya, Santos, Breno, Sued, Omar, Valencia Huamaní, Javier, Overton, Edgar T, Swaminathan, Shobha, del Rio, Carlos, Gulick, Roy M, Richardson, Paul, Sullivan, Philip, Piwowar-Manning, Estelle, Marzinke, Mark, Hendrix, Craig, Li, Maoji, Wang, Zhe, Marrazzo, Jeanne, Daar, Eric, Asmelash, Aida, Brown, Todd T, Anderson, Peter, Eshleman, Susan H, Bryan, Marcus, Blanchette, Cheryl, Lucas, Jonathan, Psaros, Christina, Safren, Steven, Sugarman, Jeremy, Scott, Hyman, Eron, Joseph J, Fields, Sheldon D, Sista, Nirupama D, Gomez-Feliciano, Kailazarid, Jennings, Andrea, Kofron, Ryan M, Holtz, Timothy H, Shin, Katherine, Rooney, James F, Smith, Kimberly Y, Spreen, William, Margolis, David, Rinehart, Alex, Adeyeye, Adeola, Cohen, Myron S, McCauley, Marybeth, Grinsztejn, Beatriz

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RegSNPs-intron: a computational framework for predicting pathogenic impact of intronic single nucleotide variants von Lin, Hai, Hargreaves, Katherine A, Li, Rudong, Reiter, Jill L, Wang, Yue, Mort, Matthew, Cooper, David N, Zhou, Yaoqi, Zhang, Chi, Eadon, Michael T, Dolan, M Eileen, Ipe, Joseph, Skaar, Todd C, Liu, Yunlong

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Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience von Udeochu, Joe C., Amin, Sadaf, Huang, Yige, Fan, Li, Torres, Eileen Ruth S., Carling, Gillian K., Liu, Bangyan, McGurran, Hugo, Coronas-Samano, Guillermo, Kauwe, Grant, Mousa, Gergey Alzaem, Wong, Man Ying, Ye, Pearly, Nagiri, Ravi Kumar, Lo, Iris, Holtzman, Julia, Corona, Carlo, Yarahmady, Allan, Gill, Michael T., Raju, Ravikiran M., Mok, Sue-Ann, Gong, Shiaoching, Luo, Wenjie, Zhao, Mingrui, Tracy, Tara E., Ratan, Rajiv R., Tsai, Li-Huei, Sinha, Subhash C., Gan, Li

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Crumbs3 Is Essential for Proper Epithelial Development and Viability von Whiteman, Eileen L., Fan, Shuling, Harder, Jennifer L., Walton, Katherine D., Liu, Chia-Jen, Soofi, Abdul, Fogg, Vanessa C., Hershenson, Marc B., Dressler, Gregory R., Deutsch, Gail H., Gumucio, Deborah L., Margolis, Ben

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Canadian Cardiovascular Harmonized National Guidelines Endeavour (C-CHANGE) guideline for the prevention and management of cardiovascular disease in primary care: 2018 update von Tobe, Sheldon W., MD MScCH, Stone, James A., MD PhD, Anderson, Todd, MD, Bacon, Simon, PhD, Cheng, Alice Y.Y., MD, Daskalopoulou, Stella S., MD PhD, Ezekowitz, Justin A., MBBCh MSc, Gregoire, Jean C., MD, Gubitz, Gord, MD, Jain, Rahul, MD MScCH, Keshavjee, Karim, MSc MD, Lindsay, Patty, RN PhD, L’Abbe, Mary, PhD, Lau, David C.W., MD PhD, Leiter, Lawrence A., MD, O’Meara, Eileen, MD, Pearson, Glen J., PharmD, Rabi, Doreen M., MD MSc, Sherifali, Diana, RN PhD, Selby, Peter, MBBS MHSc, Tu, Jack V., MD PhD, Wharton, Sean, MD PharmD, Walker, Kimberly M., MPH, Hua-Stewart, Diane, MPH, Liu, Peter P., MD

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Neoplasia risk in patients with Lynch syndrome treated with immune checkpoint blockade von Harrold, Emily C., Foote, Michael B., Rousseau, Benoit, Walch, Henry, Kemel, Yelena, Richards, Allison L., Keane, Fergus, Cercek, Andrea, Yaeger, Rona, Rathkopf, Dana, Segal, Neil H., Patel, Zalak, Maio, Anna, Borio, Matilde, O’Reilly, Eileen M., Reidy, Diane, Desai, Avni, Janjigian, Yelena Y., Murciano-Goroff, Yonina R., Carlo, Maria I., Latham, Alicia, Liu, Ying L., Walsh, Michael F., Ilson, David, Rosenberg, Jonathan E., Markowitz, Arnold J., Weiser, Martin R., Rossi, Anthony M., Vanderbilt, Chad, Mandelker, Diana, Bandlamudi, Chaitanya, Offit, Kenneth, Berger, Michael F., Solit, David B., Saltz, Leonard, Shia, Jinru, Diaz, Luis A., Stadler, Zsofia K.

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Adjuvant Lapatinib and Trastuzumab for Early Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Results From the Randomized Phase III Adjuvant Lapatinib and/or Trastu... von Piccart-Gebhart, Martine, Holmes, Eileen, Baselga, José, de Azambuja, Evandro, Dueck, Amylou C, Viale, Giuseppe, Zujewski, Jo Anne, Goldhirsch, Aron, Armour, Alison, Pritchard, Kathleen I, McCullough, Ann E, Dolci, Stella, McFadden, Eleanor, Holmes, Andrew P, Tonghua, Liu, Eidtmann, Holger, Dinh, Phuong, Di Cosimo, Serena, Harbeck, Nadia, Tjulandin, Sergei, Im, Young-Hyuck, Huang, Chiun-Sheng, Diéras, Véronique, Hillman, David W, Wolff, Antonio C, Jackisch, Christian, Lang, Istvan, Untch, Michael, Smith, Ian, Boyle, Frances, Xu, Binghe, Gomez, Henry, Suter, Thomas, Gelber, Richard D, Perez, Edith A

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A phase 1/1B trial of ADI‐PEG 20 plus nab‐paclitaxel and gemcitabine in patients with advanced pancreatic adenocarcinoma von Lowery, Maeve A., Yu, Kenneth H., Kelsen, David Paul, Harding, James J., Bomalaski, John S., Glassman, Danielle C., Covington, Christina M., Brenner, Robin, Hollywood, Ellen, Barba, Adalberto, Johnston, Amanda, Liu, Kay Chia‐Wei, Feng, Xiaoxing, Capanu, Marinela, Abou‐Alfa, Ghassan K., O'Reilly, Eileen M.

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Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group von Reshmi, Shalini C., Harvey, Richard C., Roberts, Kathryn G., Stonerock, Eileen, Smith, Amy, Jenkins, Heather, Chen, I-Ming, Valentine, Marc, Liu, Yu, Li, Yongjin, Shao, Ying, Easton, John, Payne-Turner, Debbie, Gu, Zhaohui, Tran, Thai Hoa, Nguyen, Jonathan V., Devidas, Meenakshi, Dai, Yunfeng, Heerema, Nyla A., Carroll, Andrew J., Raetz, Elizabeth A., Borowitz, Michael J., Wood, Brent L., Angiolillo, Anne L., Burke, Michael J., Salzer, Wanda L., Zweidler-McKay, Patrick A., Rabin, Karen R., Carroll, William L., Zhang, Jinghui, Loh, Mignon L., Mullighan, Charles G., Willman, Cheryl L., Gastier-Foster, Julie M., Hunger, Stephen P.

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A New Global Definition of Acute Respiratory Distress Syndrome von Matthay, Michael A, Arabi, Yaseen, Arroliga, Alejandro C, Bernard, Gordon, Bersten, Andrew D, Brochard, Laurent J, Calfee, Carolyn S, Combes, Alain, Daniel, Brian M, Ferguson, Niall D, Gong, Michelle N, Gotts, Jeffrey E, Herridge, Margaret S, Laffey, John G, Liu, Kathleen D, Machado, Flavia R, Martin, Thomas R, McAuley, Danny F, Mercat, Alain, Moss, Marc, Mularski, Richard A, Pesenti, Antonio, Qiu, Haibo, Ramakrishnan, Nagarajan, Ranieri, V Marco, Riviello, Elisabeth D, Rubin, Eileen, Slutsky, Arthur S, Thompson, B Taylor, Twagirumugabe, Theogene, Ware, Lorraine B, Wick, Katherine D

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Use, Durability, and Risks for Discontinuation of Initial and Subsequent Biologics in a Large Pediatric‐Onset IBD Cohort von Kaplan, Jess L., Liu, Chunyan, King, Eileen C., Bass, Julie A., Patel, Ashish S., Tung, Jeanne, Chen, Shiran, Lissoos, Trevor, Candela, Ninfa, Saeed, Shehzad, Colletti, Richard B., Adler, Jeremy, Baron, Howard I., Cabrera, José M., Dorsey, Jill M., Dykes, Dana M.H., Ebach, Dawn R., Garin‐Laflam, Monica P., Gold, Benjamin D., Grunow, John, Higuchi, Leslie M., Jester, Traci W., Lapsia, Sameer P., Leibowitz, Ian, Linvlle, Tiffany M., Morhardt, Tina L., Moses, Jonathan, Moulton, Dedrick, Nasiri‐Blomgren, Shaida, Niklinska‐Schirtz, B. Joanna, Ogunmola, Nicholas A., Palomo, Pablo J., Park, K.T., Pashankar, Dinesh S., Pasternak, Brad A., Radano, Marcella C., Samson, Charles M., Sandberg, Kelly C., Schaefer, Marc E., Shashidhar, Harohalli, Steiner, Steven J., Sullivan, Jillian S., Tomer, Gitit, Verstraete, Sophia G.

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Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas von Kim, Jennifer E, Patel, Mira A, Mangraviti, Antonella, Kim, Eileen S, Theodros, Debebe, Velarde, Esteban, Liu, Ann, Sankey, Eric W, Tam, Ada, Xu, Haiying, Mathios, Dimitrios, Jackson, Christopher M, Harris-Bookman, Sarah, Garzon-Muvdi, Tomas, Sheu, Mary, Martin, Allison M, Tyler, Betty M, Tran, Phuoc T, Ye, Xiaobu, Olivi, Alessandro, Taube, Janis M, Burger, Peter C, Drake, Charles G, Brem, Henry, Pardoll, Drew M, Lim, Michael

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Conversion to the Amyotrophic Lateral Sclerosis Phenotype Is Associated with Intermolecular Linked Insoluble Aggregates of SOD1 in Mitochondria von Deng, Han-Xiang, Shi, Yong, Furukawa, Yoshiaki, Zhai, Hong, Fu, Ronggen, Liu, Erdong, Gorrie, George H., Khan, Mohammad S., Hung, Wu-Yen, Bigio, Eileen H., Lukas, Thomas, Canto, Mauro C. Dal, O'Halloran, Thomas V., Siddique, Teepu

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Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer von Li, Rui, Ong, Stephanie L., Tran, Linh M., Jing, Zhe, Liu, Bin, Park, Stacy J., Huang, Zi Ling, Walser, Tonya C., Heinrich, Eileen L., Lee, Gina, Salehi-Rad, Ramin, Crosson, William P., Pagano, Paul C., Paul, Manash K., Xu, Shili, Herschman, Harvey, Krysan, Kostyantyn, Dubinett, Steven

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Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial von Lv, Jicheng, Wong, Muh Geot, Hladunewich, Michelle A, Jha, Vivekanand, Hooi, Lai Seong, Monaghan, Helen, Zhao, Minghui, Barbour, Sean, Jardine, Meg J, Reich, Heather N, Cattran, Daniel, Glassock, Richard, Levin, Adeera, Wheeler, David C, Woodward, Mark, Billot, Laurent, Stepien, Sandrine, Rogers, Kris, Chan, Tak Mao, Liu, Zhi-Hong, Johnson, David W, Cass, Alan, Feehally, John, Floege, Jürgen, Remuzzi, Giuseppe, Wu, Yangfeng, Agarwal, Rajiv, Zhang, Hong, Perkovic, Vlado

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Increased Persistent Sodium Current Due to Decreased PI3K Signaling Contributes to QT Prolongation in the Diabetic Heart von ZHONGJU LU, JIANG, Ya-Ping, WU, Chia-Yen C, BALLOU, Lisa M, SHENGNAN LIU, CARPENTER, Eileen S, ROSEN, Michael R, COHEN, Ira S, LIN, Richard Z

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