Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9 von Littler, Dene R., Gully, Benjamin S., Colson, Rhys N., Rossjohn, Jamie

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Inside-out: Antibody-binding reveals potential folding hinge-points within the SARS-CoV-2 replication co-factor nsp9 von Pan, Yue, Chandrashekaran, Indu R, Tennant, Luke, Rossjohn, Jamie, Littler, Dene R

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CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age von Menon, Tejas, Illing, Patricia T., Chaurasia, Priyanka, McQuilten, Hayley A., Shepherd, Chloe, Rowntree, Louise C., Petersen, Jan, Littler, Dene R., Khuu, Grace, Huang, Ziyi, Allen, Lilith F., Rockman, Steve, Crowe, Jane, Flanagan, Katie L., Wakim, Linda M., Nguyen, Thi H. O., Mifsud, Nicole A., Rossjohn, Jamie, Purcell, Anthony W., van de Sandt, Carolien E., Kedzierska, Katherine

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The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins? von Littler, Dene R., Harrop, Stephen J., Goodchild, Sophia C., Phang, Juanita M., Mynott, Andrew V., Jiang, Lele, Valenzuela, Stella M., Mazzanti, Michele, Brown, Louise J., Breit, Samuel N., Curmi, Paul M.G.

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Binding Studies of the Prodrug HAO472 to SARS-Cov‑2 Nsp9 and Variants von Liu, Miaomiao, Littler, Dene R, Rossjohn, Jamie, Quinn, Ronald J

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EcxAB Is a Founding Member of a New Family of Metalloprotease AB5 Toxins with a Hybrid Cholera-like B Subunit von Ng, Natasha M., Littler, Dene R., Paton, Adrienne W., Le Nours, Jérôme, Rossjohn, Jamie, Paton, James C., Beddoe, Travis

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OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gαz von Keen, Alastair C., Pedersen, Maria Hauge, Lemel, Laura, Scott, Daniel J., Canals, Meritxell, Littler, Dene R., Beddoe, Travis, Ono, Yuki, Shi, Lei, Inoue, Asuka, Javitch, Jonathan A., Lane, J. Robert

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Discovery of Anti-SARS-CoV‑2 Nsp9 Binders from Natural Products by a Native Mass Spectrometry Approach von Quinn, Ronald J., Mak, Tin, Littler, Dene R., Rossjohn, Jamie, Liu, Miaomiao

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ADP-ribosyltransferase-based biocatalysis of nonhydrolyzable NAD+ analogs von Sakari, Moona, Bhadane, Rajendra, Kumar, Sujit, Azevedo, Rita, Malakoutikhah, Morteza, Masoumi, Ahmadreza, Littler, Dene R., Härmä, Harri, Kopra, Kari, Pulliainen, Arto T.

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The Intracellular Chloride Ion Channel Protein CLIC1 Undergoes a Redox-controlled Structural Transition von Littler, Dene R., Harrop, Stephen J., Fairlie, W. Douglas, Brown, Louise J., Pankhurst, Greg J., Pankhurst, Susan, DeMaere, Matthew Z., Campbell, Terence J., Bauskin, Asne R., Tonini, Raffaella, Mazzanti, Michele, Breit, Samuel N., Curmi, Paul M.G.

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Molecular basis of cytokine receptor activation von Lopez, Angel F, Hercus, Timothy R, Ekert, Paul, Littler, Dene R, Guthridge, Mark, Thomas, Daniel, Ramshaw, Hayley S, Stomski, Frank, Perugini, Michelle, D'Andrea, Richard, Grimbaldeston, Michele, Parker, Michael W

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A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein von Littler, Dene R., Liu, Miaomiao, McAuley, Julie L., Lowery, Shea A., Illing, Patricia T., Gully, Benjamin S., Purcell, Anthony W., Chandrashekaran, Indu R., Perlman, Stanley, Purcell, Damian F.J., Quinn, Ronald J., Rossjohn, Jamie

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Crystal structures of pertussis toxin with NAD+ and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity von Sakari, Moona, Tran, Mai T., Rossjohn, Jamie, Pulliainen, Arto T., Beddoe, Travis, Littler, Dene R.

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Recognition of the antigen-presenting molecule MR1 by a Vδ3⁺ γδ T cell receptor von Rice, Michael T., von Borstel, Anouk, Chevour, Priyanka, Awad, Wael, Howson, Lauren J., Littler, Dene R., Gherardin, Nicholas A., Le Nours, Jérôme, Giles, Edward M., Berry, Richard, Godfrey, Dale I., Davey, Martin S., Rossjohn, Jamie, Gully, Benjamin S.

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Polo-box domains confer target specificity to the Polo-like kinase family von van de Weerdt, Barbara C.M., Littler, Dene R., Klompmaker, Rob, Huseinovic, Angelina, Fish, Alex, Perrakis, Anastassis, Medema, René H.

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Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02 von Anand, Sushma, Littler, Dene R., Mobbs, Jesse I., Braun, Asolina, Baker, Daniel G., Tennant, Luke, Purcell, Anthony W., Vivian, Julian P., Rossjohn, Jamie

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Crystal structure of the soluble form of the redox‐regulated chloride ion channel protein CLIC4 von Littler, Dene R., Assaad, Nagi N., Harrop, Stephen J., Brown, Louise J., Pankhurst, Greg J., Luciani, Paolo, Aguilar, Marie‐Isabel, Mazzanti, Michele, Berryman, Mark A., Breit, Samuel N., Curmi, Paul M. G.

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Structure of a fully assembled γδ T cell antigen receptor von Gully, Benjamin S., Ferreira Fernandes, João, Gunasinghe, Sachith D., Vuong, Mai T., Lui, Yuan, Rice, Michael T., Rashleigh, Liam, Lay, Chan-sien, Littler, Dene R., Sharma, Sumana, Santos, Ana Mafalda, Venugopal, Hariprasad, Rossjohn, Jamie, Davis, Simon J.

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Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 nonstructural protein 9 von Littler, Dene R., Mohanty, Biswaranjan, Lowery, Shea A., Colson, Rhys N., Gully, Benjamin S., Perlman, Stanley, Scanlon, Martin J., Rossjohn, Jamie

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A pocket guide on how to structure SARS-CoV-2 drugs and therapies von Littler, Dene R, MacLachlan, Bruce J, Watson, Gabrielle M, Vivian, Julian P, Gully, Benjamin S

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