Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis von Little, Rory F, Hertweck, Christian

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Correction: Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis von Little, Rory F, Hertweck, Christian

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The biosynthetic pathway to tetromadurin (SF2487/A80577), a polyether tetronate antibiotic von Little, Rory F, Samborskyy, Markiyan, Leadlay, Peter F, Boddy, Christopher N, Cirino, Patrick C

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Nitroreductase gene-directed enzyme prodrug therapy: insights and advances toward clinical utility von Williams, Elsie M, Little, Rory F, Mowday, Alexandra M, Rich, Michelle H, Chan-Hyams, Jasmine V E, Copp, Janine N, Smaill, Jeff B, Patterson, Adam V, Ackerley, David F

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Insect‐Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non‐Canonical Polyketide Chain Termination von Niehs, Sarah P., Kumpfmüller, Jana, Dose, Benjamin, Little, Rory F., Ishida, Keishi, Flórez, Laura V., Kaltenpoth, Martin, Hertweck, Christian

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Bacterial Pathogen Channels Medium-Sized Fatty Acids into Malleicyprol Biosynthesis von Trottmann, Felix, Fiedler, Jonas, Ishida, Keishi, Ishida-Ito, Mie, Little, Rory F., Hertweck, Christian

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Calcium‐Dependent Lipopeptide Antibiotics against Drug‐Resistant Pathogens Discovered via Host‐Dependent Heterologous Expression of a Cloned Biosynthetic Gene Cluster von Lai, Hung‐En, Woolner, V. Helen, Little, Rory F., Woolly, Ethan F., Keyzers, Robert A., Owen, Jeremy G.

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Analysis of the Valgamicin Biosynthetic Pathway Reveals a General Mechanism for Cyclopropanol Formation across Diverse Natural Product Scaffolds von Little, Rory F., Trottmann, Felix, Hashizume, Hideki, Preissler, Miriam, Unger, Sandra, Sawa, Ryuichi, Kries, Hajo, Pidot, Sacha, Igarashi, Masayuki, Hertweck, Christian

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Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections von Copp, Janine N., Pletzer, Daniel, Brown, Alistair S., Van der Heijden, Joris, Miton, Charlotte M., Edgar, Rebecca J., Rich, Michelle H., Little, Rory F., Williams, Elsie M., Hancock, Robert E. W., Tokuriki, Nobuhiko, Ackerley, David F.

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A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening von Rich, Michelle H., Sharrock, Abigail V., Mulligan, Timothy S., Matthews, Frazer, Brown, Alistair S., Lee-Harwood, Hannah R., Williams, Elsie M., Copp, Janine N., Little, Rory F., Francis, Jenni J.B., Horvat, Claire N., Stevenson, Luke J., Owen, Jeremy G., Saxena, Meera T., Mumm, Jeff S., Ackerley, David F.

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Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues von Hall, Kelsi R, Robins, Katherine J, Williams, Elsie M, Rich, Michelle H, Calcott, Mark J, Copp, Janine N, Little, Rory F, Schwörer, Ralf, Evans, Gary B, Patrick, Wayne M, Ackerley, David F

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Calcium‐Dependent Lipopeptide Antibiotics against Drug‐Resistant Pathogens Discovered via Host‐Dependent Heterologous Expression of a Cloned Biosynthetic Gene Cluster von Lai, Hung‐En, Woolner, V. Helen, Little, Rory F., Woolly, Ethan F., Keyzers, Robert A., Owen, Jeremy G.

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Insect‐Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non‐Canonical Polyketide Chain Termination von Niehs, Sarah P., Kumpfmüller, Jana, Dose, Benjamin, Little, Rory F., Ishida, Keishi, Flórez, Laura V., Kaltenpoth, Martin, Hertweck, Christian

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The biosynthetic pathway to tetromadurin von Little, Rory F, Samborskyy, Markiyan, Leadlay, Peter F, Boddy, Christopher N, Cirino, Patrick C

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An intramodular thioesterase domain catalyses chain release in the biosynthesis of a cytotoxic virulence factor von Little, Rory, Trottmann, Felix, Preissler, Miriam, Hertweck, Christian

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Enzymatic Ring Formation in Polyether Tetronate Antibiotic Biosynthesis von Little, Rory Fox

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Unexpected enzyme-catalysed [4+2] cycloaddition and rearrangement in polyether antibiotic biosynthesis von Little, Rory, Paiva, Fernanda C. R., Jenkins, Robert, Hong, Hui, Sun, Yuhui, Demydchuk, Yuliya, Samborskyy, Markiyan, Tosin, Manuela, Leeper, Finian J., Dias, Marcio V. B., Leadlay, Peter F.

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The Lost History of Apprendi and the Blakely Petition for Rehearing von LITTLE, RORY K., CHEN, TERESA

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Unexpected enzyme-catalysed 4+2 cycloaddition and rearrangement in polyether antibiotic biosynthesis von Little, Rory, Paiva, Fernanda C R, Jenkins, Rob, Hong, Hui, Sun, Yuhui, Demydchuk, Yuliya, Samborskyy, Markiyan, Tosin, Manuela, Leeper, Finian J, Dias, Marcio V B, Leadlay, Peter F

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Good Enough for Government Work? The Tension Between Uniformity and Differing Regional Values in Administering the Federal Death Penalty von Little, Rory K.

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