Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling von Liss, Martin, Radke, Michael H, Eckhard, Jamina, Neuenschwander, Martin, Dauksaite, Vita, von Kries, Jens-Peter, Gotthardt, Michael

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iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy von Briganti, Francesca, Sun, Han, Wei, Wu, Wu, Jingyan, Zhu, Chenchen, Liss, Martin, Karakikes, Ioannis, Rego, Shannon, Cipriano, Andrea, Snyder, Michael, Meder, Benjamin, Xu, Zhenyu, Millat, Gilles, Gotthardt, Michael, Mercola, Mark, Steinmetz, Lars M.

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Establishment of a Neuroepithelial Barrier by Claudin5a Is Essential for Zebrafish Brain Ventricular Lumen Expansion von Zhang, Jingjing, Piontek, Jörg, Wolburg, Hartwig, Piehl, Christian, Liss, Martin, Otten, Cécile, Christ, Annabel, Willnow, Thomas E., Blasig, Ingolf E., Abdelilah-Seyfried, Salim, Dawid, Igor B.

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SLM2 Is A Novel Cardiac Splicing Factor Involved in Heart Failure due to Dilated Cardiomyopathy von Boeckel, Jes-Niels, Möbius-Winkler, Maximilian, Müller, Marion, Rebs, Sabine, Eger, Nicole, Schoppe, Laura, Tappu, Rewati, Kokot, Karoline E., Kneuer, Jasmin M., Gaul, Susanne, Bordalo, Diana M., Lai, Alan, Haas, Jan, Ghanbari, Mahsa, Drewe-Boss, Philipp, Liss, Martin, Katus, Hugo A., Ohler, Uwe, Gotthardt, Michael, Laufs, Ulrich, Streckfuss-Bömeke, Katrin, Meder, Benjamin

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RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing von Guo, Wei, Schafer, Sebastian, Greaser, Marion L, Radke, Michael H, Liss, Martin, Govindarajan, Thirupugal, Maatz, Henrike, Schulz, Herbert, Li, Shijun, Parrish, Amanda M, Dauksaite, Vita, Vakeel, Padmanabhan, Klaassen, Sabine, Gerull, Brenda, Thierfelder, Ludwig, Regitz-Zagrosek, Vera, Hacker, Timothy A, Saupe, Kurt W, Dec, G William, Ellinor, Patrick T, MacRae, Calum A, Spallek, Bastian, Fischer, Robert, Perrot, Andreas, Özcelik, Cemil, Saar, Kathrin, Hubner, Norbert, Gotthardt, Michael

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Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance von Slater, Rebecca E, Strom, Joshua G, Methawasin, Mei, Liss, Martin, Gotthardt, Michael, Sweitzer, Nancy, Granzier, Henk L

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Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy von Sedaghat-Hamedani, Farbod, Haas, Jan, Zhu, Feng, Geier, Christian, Kayvanpour, Elham, Liss, Martin, Lai, Alan, Frese, Karen, Pribe-Wolferts, Regina, Amr, Ali, Li, Daniel Tian, Samani, Omid Shirvani, Carstensen, Avisha, Bordalo, Diana Martins, Müller, Marion, Fischer, Christine, Shao, Jing, Wang, Jing, Nie, Ming, Yuan, Li, Haßfeld, Sabine, Schwartz, Christine, Zhou, Min, Zhou, Zihua, Shu, Yanwen, Wang, Min, Huang, Kai, Zeng, Qiutang, Cheng, Longxian, Fehlmann, Tobias, Ehlermann, Philipp, Keller, Andreas, Dieterich, Christoph, Streckfuß-Bömeke, Katrin, Liao, Yuhua, Gotthardt, Michael, Katus, Hugo A, Meder, Benjamin

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RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis von Zhang, Yanghai, Wang, Chunyan, Sun, Mingming, Jin, Yutong, Braz, Camila Urbano, Khatib, Hasan, Hacker, Timothy A., Liss, Martin, Gotthardt, Michael, Granzier, Henk, Ge, Ying, Guo, Wei

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Abstract 891: Phosphorylation of RNA Binding Motif 20 is a Novel Target to Reduce Myocardial Stiffness in Diastolic Dysfunction von Sun, Mingming, Jin, Yutong, Zhu, Chaoqun, Rexiati, Maimaiti, Cai, Hanfang, Liss, Martin, Gotthardt, Michael, Ge, Ying, Guo, Wei

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RBM20 ASOs improve ventricular filling in a mouse model with increased titin-based stiffness von Badillo Lisakowski, Victor, Radke, Michael H., Britto-Borges, Thiago, Kubli, Dieter, Jüttner, René, Parakkat, Pragati, López Carballo, Jacobo, Hüttemeister, Judith, Liss, Martin, Hansen, Arne, Dieterich, Christoph, Mullick, Adam, Gotthardt, Michael

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Abstract 10966: Characterization of the Novel Cardiac Splicing Factor Slm2 in Heart Failure, Which Regulates Splicing of Titin von Boeckel, Jes-Niels, Moebius-Winkler, Maximilian Nicolas, Müller, Marion, Rebs, Sabine, Eger, Nicole, Schoppe, Laura, Tappu, Rewatti, Kokot, Karoline Elizabeth, Kneuer, Jasmin M, Gaul, Susanne, martins bordalo, diana, lai, alain, Haas, Jan, Ghanbari, Mahsa, Drewe-Boss, Philipp, Liss, Martin, Katus, Hugo A, Ohler, Uwe, gotthardt, Michael, Laufs, Ulrich, Streckfuß-Bömeke, Katrin, Meder, Benjamin

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RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing von Maatz, Henrike, Jens, Marvin, Liss, Martin, Schafer, Sebastian, Heinig, Matthias, Kirchner, Marieluise, Adami, Eleonora, Rintisch, Carola, Dauksaite, Vita, Radke, Michael H, Selbach, Matthias, Barton, Paul J R, Cook, Stuart A, Rajewsky, Nikolaus, Gotthardt, Michael, Landthaler, Markus, Hubner, Norbert

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Loss of Cardiac Splicing Regulator RBM20 Is Associated With Early-Onset Atrial Fibrillation von Vad, Oliver B., Angeli, Elisavet, Liss, Martin, Ahlberg, Gustav, Andreasen, Laura, Christophersen, Ingrid E., Hansen, Camilla C., Møller, Sophie, Hellsten, Ylva, Haunsoe, Stig, Tveit, Arnljot, Svendsen, Jesper H., Gotthardt, Michael, Lundegaard, Pia R., Olesen, Morten S.

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Involvement of claudins in zebrafish brain ventricle morphogenesis von Zhang, Jingjing, Liss, Martin, Wolburg, Hartwig, Blasig, Ingolf E., Abdelilah-Seyfried, Salim

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The Cost of Treatment of Skeletal-Related Events in Patients with Bone Metastases from Lung Cancer von Delea, Thomas, Langer, Corey, McKiernan, James, Liss, Martin, Edelsberg, John, Brandman, Jane, Sung, Jennifer, Raut, Monika, Oster, Gerry

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Response to a Letter to the Editor from Coiffier Regarding “Effect of Patient Exclusion Criteria on the Efficacy of Erythropoiesis‐Stimulating Agents in Patients with Cancer‐Relate... von Littlewood, Timothy J., Schenkel, Brad, Liss, Martin

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Response to “Effect of Patient Exclusion Criteria on the Efficacy of Erythropoiesis‐Stimulating Agents in Patients with Cancer‐Related Anemia” von Coiffier, Bertrand

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Effect of Patient Exclusion Criteria on the Efficacy of Erythropoiesis‐Stimulating Agents in Patients with Cancer‐Related Anemia von Littlewood, Timothy J., Schenkel, Brad, Liss, Martin

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O-9 Cost of skeletal complications in patients with bone metastases of lung cancer von Delea, Thomas, McKiernan, James, Liss, Martin, Edelsberg, John, Brandman, Jane, Sung, Jennifer, Raut, Monika, Oster, Gerry

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Beverage dispensing prevention von STENHAGE, ULF, EMDELIUS, NIKOLAJ, LENK MARTIN, LISS MARTIN

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