Senotherapeutic drugs for human intervertebral disc degeneration and low back pain von Cherif, Hosni, Bisson, Daniel G, Mannarino, Matthew, Rabau, Oded, Ouellet, Jean A, Haglund, Lisbet

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3D-Printed ABS and PLA Scaffolds for Cartilage and Nucleus Pulposus Tissue Regeneration von Rosenzweig, Derek H, Carelli, Eric, Steffen, Thomas, Jarzem, Peter, Haglund, Lisbet

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Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain von Tansley, Shannon, Uttam, Sonali, Ureña Guzmán, Alba, Yaqubi, Moein, Pacis, Alain, Parisien, Marc, Deamond, Haley, Wong, Calvin, Rabau, Oded, Brown, Nicole, Haglund, Lisbet, Ouellet, Jean, Santaguida, Carlo, Ribeiro-da-Silva, Alfredo, Tahmasebi, Soroush, Prager-Khoutorsky, Masha, Ragoussis, Jiannis, Zhang, Ji, Salter, Michael W., Diatchenko, Luda, Healy, Luke M., Mogil, Jeffrey S., Khoutorsky, Arkady

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Three-Dimensional Printed Polylactic Acid Scaffolds Promote Bone-like Matrix Deposition in Vitro von Fairag, Rayan, Rosenzweig, Derek H, Ramirez-Garcialuna, Jose L, Weber, Michael H, Haglund, Lisbet

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Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain von Wuertz, Karin, Haglund, Lisbet

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Single-Cell RNA-Seq Analysis of Cells from Degenerating and Non-Degenerating Intervertebral Discs from the Same Individual Reveals New Biomarkers for Intervertebral Disc Degenerati... von Cherif, Hosni, Mannarino, Matthew, Pacis, Alain Sarabia, Ragoussis, Jiannis, Rabau, Oded, Ouellet, Jean A, Haglund, Lisbet

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Automated biofabrication of anisotropic dense fibrin gels accelerate osteoblastic differentiation of seeded mesenchymal stem cells von Griffanti, Gabriele, Fairag, Rayan, Rosenzweig, Derek H., Haglund, Lisbet, Nazhat, Showan N.

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Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin von Mannarino, Matthew, Cherif, Hosni, Li, Li, Sheng, Kai, Rabau, Oded, Jarzem, Peter, Weber, Michael H, Ouellet, Jean A, Haglund, Lisbet

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Physiological loading can restore the proteoglycan content in a model of early IVD degeneration von Gawri, Rahul, Moir, Janet, Ouellet, Jean, Beckman, Lorne, Steffen, Thomas, Roughley, Peter, Haglund, Lisbet

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Curcumin and o-Vanillin Exhibit Evidence of Senolytic Activity in Human IVD Cells In Vitro von Cherif, Hosni, Bisson, Daniel G, Jarzem, Peter, Weber, Michael, Ouellet, Jean A, Haglund, Lisbet

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DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics von Tam, Vivian, Chen, Peikai, Yee, Anita, Solis, Nestor, Klein, Theo, Kudelko, Mateusz, Sharma, Rakesh, Chan, Wilson Cw, Overall, Christopher M, Haglund, Lisbet, Sham, Pak C, Cheah, Kathryn Song Eng, Chan, Danny

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Uncovering the secretome of mesenchymal stromal cells exposed to healthy, traumatic, and degenerative intervertebral discs: a proteomic analysis von Wangler, Sebastian, Kamali, Amir, Wapp, Christina, Wuertz-Kozak, Karin, Häckel, Sonja, Fortes, Claudia, Benneker, Lorin M, Haglund, Lisbet, Richards, R Geoff, Alini, Mauro, Peroglio, Marianna, Grad, Sibylle

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DNA Methylation of SPARC and Chronic Low Back Pain von Tajerian, Maral, Alvarado, Sebastian, Millecamps, Magali, Dashwood, Thomas, Anderson, Kathleen M, Haglund, Lisbet, Ouellet, Jean, Szyf, Moshe, Stone, Laura S

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o-Vanillin Modulates Cell Phenotype and Extracellular Vesicles of Human Mesenchymal Stem Cells and Intervertebral Disc Cells von Li, Li, Sheng, Kai, Mannarino, Matthew, Jarzem, Peter, Cherif, Hosni, Haglund, Lisbet

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Development of an Organ Culture System for Long-Term Survival of the Intact Human Intervertebral Disc von GAWRI, Rahul, MWALE, Fackson, OUELLET, Jean, ROUGHLEY, Peter J, STEFFEN, Thomas, ANTONIOU, John, HAGLUND, Lisbet

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The C-terminal Peptide of Chondroadherin Modulates Cellular Activity by Selectively Binding to Heparan Sulfate Chains von Haglund, Lisbet, Tillgren, Viveka, Önnerfjord, Patrik, Heinegård, Dick

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Optimizing Design Parameters of PLA 3D-Printed Scaffolds for Bone Defect Repair von Dussault, Alexandrine, Pitaru, Audrey A., Weber, Michael H., Haglund, Lisbet, Rosenzweig, Derek H., Villemure, Isabelle

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A Composite Lactide-Mineral 3D-Printed Scaffold for Bone Repair and Regeneration von Fairag, Rayan, Li, Li, Ramirez-GarciaLuna, Jose Luis, Taylor, M. Scott, Gaerke, Brian, Weber, Michael H., Rosenzweig, Derek H., Haglund, Lisbet

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Senolytic Combination Treatment Is More Potent Than Single Drugs in Reducing Inflammatory and Senescence Burden in Cells from Painful Degenerating IVDs von Mannarino, Matthew, Wu-Martinez, Oliver, Sheng, Kai, Li, Li, Navarro-Ramirez, Rodrigo, Jarzem, Peter, Ouellet, Jean A., Cherif, Hosni, Haglund, Lisbet

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Low-frequency high-magnitude mechanical strain of articular chondrocytes activates p38 MAPK and induces phenotypic changes associated with osteoarthritis and pain von Rosenzweig, Derek H, Quinn, Thomas M, Haglund, Lisbet

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