Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial von Ribas, Antoni, Prof, Puzanov, Igor, MD, Dummer, Reinhard, Prof, Schadendorf, Dirk, Prof, Hamid, Omid, MD, Robert, Caroline, Prof, Hodi, F Stephen, MD, Schachter, Jacob, Prof, Pavlick, Anna C, MD, Lewis, Karl D, MD, Cranmer, Lee D, MD, Blank, Christian U, MD, O'Day, Steven J, MD, Ascierto, Paolo A, Prof, Salama, April K S, MD, Margolin, Kim A, Prof, Loquai, Carmen, MD, Eigentler, Thomas K, MD, Gangadhar, Tara C, MD, Carlino, Matteo S, MBBS, Agarwala, Sanjiv S, Prof, Moschos, Stergios J, MD, Sosman, Jeffrey A, Prof, Goldinger, Simone M, MD, Shapira-Frommer, Ronnie, MD, Gonzalez, Rene, Prof, Kirkwood, John M, Prof, Wolchok, Jedd D, Prof, Eggermont, Alexander, Prof, Li, Xiaoyun Nicole, PhD, Zhou, Wei, PhD, Zernhelt, Adriane M, BS, Lis, Joy, BSN, Ebbinghaus, Scot, MD, Kang, S Peter, MD, Daud, Adil, Prof

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Randomized double-blind safety study of enoxaparin versus unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes treated with tirofiban and aspir... von Cohen, Marc, Théroux, Pierre, Borzak, Steven, Frey, Martin J., White, Harvey D., Van Mieghem, W., Senatore, Fred, Lis, Joy, Mukherjee, Robin, Harris, Kathy, Bigonzi, Frederique

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A randomized controlled comparison of pembrolizumab and chemotherapy in patients with ipilimumab-refractory melanoma von Dummer, Reinhard, Daud, Adil, Puzanov, Igor, Hamid, Omid, Schadendorf, Dirk, Robert, Caroline, Schachter, Jacob, Pavlick, Anna, Gonzalez, Rene, Hodi, F, Cranmer, Lee D, Blank, Christian, O’Day, Steven J, Ascierto, Paolo A, Salama, April K S, Li, Nicole Xiaoyun, Zhou, Wei, Lis, Joy, Ebbinghaus, Scot, Kang, Peter S, Ribas, Antoni

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Randomized double-blind safety study of enoxaparin versus unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes treated with tirofiban and asoir... von COHEN, Marc, THEROUX, Pierre, BIGONZI, Frederique, BORZAK, Steven, FREY, Martin J, WHITE, Harvey D, VAN MIEGHEM, W, SENATORE, Fred, LIS, Joy, MUKHERIEE, Robin, HARRIS, Kathy

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Randomized double-blind safety study of enoxaparin versus unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes treated with tirofiban and aspir... von Cohen, Marc, Théroux, Pierre, Borzak, Steven, Frey, Martin J, White, Harvey D, Van Mieghem, W, Senatore, Fred, Lis, Joy, Mukherjee, Robin, Harris, Kathy, Bigonzi, Frederique

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A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models von van Lengerich, Bettina, Zhan, Lihong, Xia, Dan, Chan, Darren, Joy, David, Park, Joshua I., Tatarakis, David, Calvert, Meredith, Hummel, Selina, Lianoglou, Steve, Pizzo, Michelle E., Prorok, Rachel, Thomsen, Elliot, Bartos, Laura M., Beumers, Philipp, Capell, Anja, Davis, Sonnet S., de Weerd, Lis, Dugas, Jason C., Duque, Joseph, Earr, Timothy, Gadkar, Kapil, Giese, Tina, Gill, Audrey, Gnörich, Johannes, Ha, Connie, Kannuswamy, Malavika, Kim, Do Jin, Kunte, Sebastian T., Kunze, Lea H., Lac, Diana, Lechtenberg, Kendra, Leung, Amy Wing-Sze, Liang, Chun-Chi, Lopez, Isabel, McQuade, Paul, Modi, Anuja, Torres, Vanessa O., Nguyen, Hoang N., Pesämaa, Ida, Propson, Nicholas, Reich, Marvin, Robles-Colmenares, Yaneth, Schlepckow, Kai, Slemann, Luna, Solanoy, Hilda, Suh, Jung H., Thorne, Robert G., Vieira, Chandler, Wind-Mark, Karin, Xiong, Ken, Zuchero, Y. Joy Yu, Diaz, Dolo, Dennis, Mark S., Huang, Fen, Scearce-Levie, Kimberly, Watts, Ryan J., Haass, Christian, Lewcock, Joseph W., Di Paolo, Gilbert, Brendel, Matthias, Sanchez, Pascal E., Monroe, Kathryn M.

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Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision von Baldridge, Dustin, Wangler, Michael F, Bowman, Angela N, Yamamoto, Shinya, Schedl, Tim, Pak, Stephen C, Postlethwait, John H, Shin, Jimann, Solnica-Krezel, Lilianna, Bellen, Hugo J, Westerfield, Monte

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EFEMP1 haploinsufficiency causes a Marfan‐like hereditary connective tissue disorder von Forghani, Irman, Adam, Margaret, Azamian, Mahshid S., Baker, Eva, Baldridge, Dustin, Bale, Jim, Beck, Anita, Berg‐Rood, Beverly, Berry, Gerard T., Bican, Anna, Boyd, Brenna, Briere, Lauren C., Burke, Elizabeth A., Burrage, Lindsay C., Byers, Peter, Carey, John, Chang, Ta Chen Peter, Cogan, Joy D., Colley, Heather A., D'Souza, Precilla, Dasari, Surendra, Dell'Angelica, Esteban C., Duncan, Laura, Eckstein, David J., Emrick, Lisa T., Eng, Christine M., Esteves, Cecilia, Fernandez, Liliana, Fieg, Elizabeth L., Forghani, Irman, Gochuico, Bernadette, Grajewski, Alana, Hahn, Sihoun, Hamid, Rizwan, High, Frances, Hing, Anne, Hisama, Fuki M., Holm, Ingrid A., Huang, Yong, Jamal, Fariha, Jayadev, Suman, Kohler, Jennefer N., Krakow, Deborah, Kravets, Elijah, Koziura, Mary, Lam, Byron, Lam, Christina, Lanza, Ian R., LeBlanc, Kimberly, Lee, Brendan H., Lee, Hane, Levitt, Roy, Liu, Pengfei, Maas, Richard L., Macnamara, Ellen F., Maduro, Valerie V., Majcherska, Marta M., Manolio, Teri A., Marth, Gabor, Martínez‐Agosto, Julian A., Marwaha, Shruti, McCauley, Jacob, McConkie‐Rosell, Allyn, McGee, Elisabeth, Might, Matthew, Mirzaa, Ghayda, Moretti, Paolo M., Mosbrook‐Davis, Deborah, Murdock, David R., Nieves‐Rodriguez, Shirley, Parker, Neil H., Phillips, John A., Power, Bradley, Pusey, Barbara N., Quinlan, Aaron, Raskind, Wendy, Sacco, Ralph, Sampson, Jacinda B., Saporta, Mario, Shin, Jimann, Silverman, Edwin K., Sinsheimer, Janet S., Solem, Emily, Stoler, Joan M., Sun, Angela, Tabor, Holly K., Tan, Amelia L. M., Telischi, Fred, Tifft, Cynthia J., Toro, Camilo, Tucker, Brianna M., Vogel, Tiphanie P., Wambach, Jennifer, Wang, Lee‐kai, Wegner, Daniel, Wenger, Tara, Westerfield, Monte, Wolfe, Lynne A., Zein, Wadih, Zuchner, Stephan

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H4C5 missense variant leads to a neurodevelopmental phenotype overlapping with Angelman syndrome von Bivona, Stephanie, Peart, LéShon, Guo, Shengru, Adam, Margaret, Agrawal, Pankaj B., Alvey, Justin, Balasubramanyam, Ashok, Bayrak‐Toydemir, Pinar, Beck, Anita, Bohnsack, John, Bonner, Devon, Botto, Lorenzo, Butte, Manish J., Chanprasert, Sirisak, Clark, Gary D., Coggins, Matthew, Cope, Heidi, Craigen, William J., Dorrani, Naghmeh, Doss, Argenia L., Douine, Emilie D., Earl, Dawn, Eckstein, David J., Emrick, Lisa T., Ferreira, Carlos, Fisher, Paul G., Gahl, William A., Goldman, Alica M., Goldstein, David B., Grajewski, Alana, Groden, Catherine A., Hamid, Rizwan, Hanchard, Neil A., Hassey, Kelly, Hayes, Nichole, Horike‐Pyne, Martha, Huang, Alden, Huang, Yong, Huryn, Laryssa, Isasi, Rosario, Jarvik, Gail P., Kennedy, Jennifer, Kiley, Dana, Kohane, Isaac S., Krakow, Deborah, Krasnewich, Donna M., Kravets, Elijah, Korrick, Susan, Koziura, Mary, Krier, Joel B., Lalani, Seema R., Lam, Christina, LaMoure, Grace L., Lee, Brendan H., Lincoln, Sharyn A., Loo, Sandra K., Maduro, Valerie V., Majcherska, Marta M., Malicdan, May Christine V., Mamounas, Laura A., Mao, Rong, Maravilla, Kenneth, Marom, Ronit, Martin, Beth A., Marwaha, Shruti, Mefford, Heather, Morava, Eva, Mulvihill, John J., Nakano‐Okuno, Mariko, Nath, Avi, Nickerson, Deborah, Nieves‐Rodriguez, Shirley, Pallais, J. Carl, Raskind, Wendy, Renteria, Genecee, Ruzhnikov, Maura, Samson, Susan L., Shashi, Vandana, Silverman, Edwin K., Sisco, Kathy, Solnica‐Krezel, Lilianna, Solomon, Ben, Sun, Angela, Sweetser, David A., Tan, Queenie K.‐G., Thorson, Willa, Thurm, Audrey, Tran, Alyssa A., Vanderver, Adeline, Velinder, Matt, Viskochil, Dave, Wallace, Stephanie, Walsh, Chris A., Wambach, Jennifer, Wan, Jijun, Ward, Patricia A., Wener, Mark, Wenger, Tara, Yang, John, Yousef, Muhammad

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On the Mechanisms Governing Aluminum-Mediated Solid-Phase Epitaxy of Silicon von Civale, Yann, Vastola, Guglielmo, Nanver, Lis K., Mary-Joy, Rani, Kim, Jae-Ryoung

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Genome sequencing reveals novel noncoding variants in PLA2G6 and LMNB1 causing progressive neurologic disease von Adams, David R., Bademci, Guney, Baker, Eva, Baldridge, Dustin, Bale, Jim, Barbouth, Deborah, Beck, Anita, Berg‐Rood, Beverly, Berry, Gerard T., Brokamp, Elly, Burke, Elizabeth A., Burrage, Lindsay C., Byers, Peter, Carey, John, Chang, Ta Chen Peter, Coakley, Terra R., Colley, Heather A., Cooper, Cynthia M., Dasari, Surendra, Dayal, Jyoti G., Duncan, Laura, Eng, Christine M., Esteves, Cecilia, Fernandez, Liliana, Fieg, Elizabeth L., Forghani, Irman, Glass, Ian, Gochuico, Bernadette, Golden‐Grant, Katie, Goldrich, Madison P., Grajewski, Alana, Hahn, Sihoun, Hamid, Rizwan, Hing, Anne, Holm, Ingrid A., Huang, Yong, Jamal, Fariha, Jayadev, Suman, Kohane, Isaac S., Kohler, Jennefer N., Kravets, Elijah, Lam, Byron, Lam, Christina, Lee, Hane, Levitt, Roy, Liu, Pengfei, Liu, Xue Zhong, Longo, Nicola, Maas, Richard L., Macnamara, Ellen F., Maduro, Valerie V., Manolio, Teri A., Marth, Gabor, Martínez‐Agosto, Julian A., McCauley, Jacob, McConkie‐Rosell, Allyn, McGee, Elisabeth, Might, Matthew, Moretti, Paolo M., Mosbrook‐Davis, Deborah, Nagy, Anna, Nelson, Stan F., Nicholas, Sarah K., Orengo, James P., Pace, Laura, Pallais, J. Carl, Parker, Neil H., Phillips, John A., Power, Bradley, Pusey, Barbara N., Quinlan, Aaron, Rao, Deepak A., Robertson, Amy K., Rosenwasser, Natalie, Rossignol, Francis, Sacco, Ralph, Sampson, Jacinda B., Saporta, Mario, Scott, C. Ron, Scott, Daryl A., Shin, Jimann, Silverman, Edwin K., Sinsheimer, Janet S., Solem, Emily, Stoler, Joan M., Sullivan, Jennifer A., Tifft, Cynthia J., Toro, Camilo, Vanderver, Adeline, Vogel, Tiphanie P., Walker, Melissa, Wambach, Jennifer, Wang, Lee‐kai, Ward, Patricia A., Wegner, Daniel, Wenger, Tara, Westerfield, Monte, Wolfe, Lynne A., Woods, Jeremy D., Yang, John

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A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models von van Lengerich, Bettina, Zhan, Lihong, Xia, Dan, Chan, Darren, Joy, David, Park, Joshua I, Tatarakis, David, Calvert, Meredith, Hummel, Selina, Lianoglou, Steve, Pizzo, Michelle E, Prorok, Rachel, Thomsen, Elliot, Bartos, Laura M, Beumers, Philipp, Capell, Anja, Davis, Sonnet S, de Weerd, Lis, Dugas, Jason C, Duque, Joseph, Earr, Timothy, Gadkar, Kapil, Giese, Tina, Gill, Audrey, Gnoerich, Johannes, Ha, Connie, Kannuswamy, Malavika, Kim, Do Jin, Kunte, Sebastian T, Kunze, Lea H, Lac, Diana, Lechtenberg, Kendra, Leung, Amy Wing-Sze, Liang, Chun-Chi, Lopez, Isabel, McQuade, Paul, Modi, Anuja, Torres, Vanessa O, Nguyen, Hoang N, Pesaemaa, Ida, Propson, Nicholas, Reich, Marvin, Robles-Colmenares, Yaneth, Schlepckow, Kai, Slemann, Luna, Solanoy, Hilda, Suh, Jung H, Thorne, Robert G, Vieira, Chandler, Wind-Mark, Karin, Xiong, Ken, Zuchero, Y. Joy Yu, Diaz, Dolo, Dennis, Mark S, Huang, Fen, Scearce-Levie, Kimberly, Watts, Ryan J, Haass, Christian, Lewcock, Joseph W, Di Paolo, Gilbert, Brendel, Matthias, Sanchez, Pascal E, Monroe, Kathryn M

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A concurrent cohort study of oral contraceptive users from the VAMP research bank von Lis, Yvonne, Spitzer, Walter O., Mann, Ronald D., Chukwujindu, Joy, Thorogood, Margaret, Evans, Stephen, Suissa, Samy, Lelorier, Jacques

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