Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core von Sivaprakasam, Prasanna, Han, Xiaojun, Civiello, Rita L, Jacutin-Porte, Swanee, Kish, Kevin, Pokross, Matt, Lewis, Hal A, Ahmed, Nazia, Szapiel, Nicolas, Newitt, John A, Baldwin, Eric T, Xiao, Hong, Krause, Carol M, Park, Hyunsoo, Nophsker, Michelle, Lippy, Jonathan S, Burton, Catherine R, Langley, David R, Macor, John E, Dubowchik, Gene M

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Discovery of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of adaptor protein 2-associated kinase 1 for the treatment of pain von Dzierba, Carolyn D., Dasgupta, Bireshwar, Karageorge, George, Kostich, Walter, Hamman, Brian, Allen, Jason, Esposito, Kim M., Padmanabha, Ramesh, Grace, James, Lentz, Kimberley, Morrison, John, Morgan, Daniel, Easton, Amy, Bourin, Clotilde, Browning, Marc R., Rajamani, Ramkumar, Good, Andrew, Parker, Dawn D., Muckelbauer, Jodi K., Khan, Javed, Camac, Daniel, Ghosh, Kaushik, Halan, Vivek, Lippy, Jonathan S., Santone, Kenneth S., Denton, R. Rex, Westphal, Ryan, Bristow, Linda J., Conway, Charles M., Bronson, Joanne J., Macor, John E.

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Discovery, Structure–Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2‑Associated Kinase 1 (AAK1) Inhibitors for the Treatmen... von Hartz, Richard A, Ahuja, Vijay T, Nara, Susheel J, Kumar, C.M. Vijaya, Brown, Jeffrey M, Bristow, Linda J, Rajamani, Ramkumar, Muckelbauer, Jodi K, Camac, Daniel, Kiefer, Susan E, Hunihan, Lisa, Gulianello, Michael, Lewis, Martin, Easton, Amy, Lippy, Jonathan S, Surti, Neha, Pattipati, Sreenivasulu N, Dokania, Manoj, Elavazhagan, Saravanan, Dandapani, Kumaran, Hamman, Brian D, Allen, Jason, Kostich, Walter, Bronson, Joanne J, Macor, John E, Dzierba, Carolyn D

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Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2‑Associated Kinase 1 Inhibitors von Hartz, Richard A, Ahuja, Vijay T, Nara, Susheel J, Kumar, C. M. Vijaya, Manepalli, Raju K. V. L. P, Sarvasiddhi, Sarat Kumar, Honkhambe, Swarnamba, Patankar, Vidya, Dasgupta, Bireshwar, Rajamani, Ramkumar, Muckelbauer, Jodi K, Camac, Daniel M, Ghosh, Kaushik, Pokross, Matthew, Kiefer, Susan E, Brown, Jeffrey M, Hunihan, Lisa, Gulianello, Michael, Lewis, Martin, Lippy, Jonathan S, Surti, Neha, Hamman, Brian D, Allen, Jason, Kostich, Walter A, Bronson, Joanne J, Macor, John E, Dzierba, Carolyn D

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Conversion of carbazole carboxamide based reversible inhibitors of Bruton’s tyrosine kinase (BTK) into potent, selective irreversible inhibitors in the carbazole, tetrahydrocarbazo... von Liu, Qingjie, Batt, Douglas G., Chaudhry, Charu, Lippy, Jonathan S., Pattoli, Mark A., Surti, Neha, Xu, Songmei, Carter, Percy H., Burke, James R., Tino, Joseph A.

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Trends in Kinase Selectivity: Insights for Target Class-Focused Library Screening von Posy, Shana L, Hermsmeier, Mark A, Vaccaro, Wayne, Ott, Karl-Heinz, Todderud, Gordon, Lippy, Jonathan S, Trainor, George L, Loughney, Deborah A, Johnson, Stephen R

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Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton’s tyrosine kinase (BTK) and Janus kinase 2 (JAK2) von Liu, Qingjie, Batt, Douglas G., Lippy, Jonathan S., Surti, Neha, Tebben, Andrew J., Muckelbauer, Jodi K., Chen, Lin, An, Yongmi, Chang, Chiehying, Pokross, Matt, Yang, Zheng, Wang, Haiqing, Burke, James R., Carter, Percy H., Tino, Joseph A.

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Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors von Hynes, John, Wu, Hong, Kempson, James, Duan, James J.-W., Lu, Zhonghui, Jiang, Bin, Stachura, Sylwia, Tokarski, John S., Sack, John S., Khan, Javed A., Lippy, Jonathan S., Zhang, Rosemary F., Pitt, Sidney, Shen, Guoxiang, Gillooly, Kate, McIntyre, Kim, Carter, Percy H., Barrish, Joel C., Nadler, Steven G., Salter-Cid, Luisa M., Fura, Aberra, Schieven, Gary L., Pitts, William J., Wrobleski, Stephen T.

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Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis von Spergel, Steven H, Mertzman, Michael E, Kempson, James, Guo, Junqing, Stachura, Sylwia, Haque, Lauren, Lippy, Jonathan S, Zhang, Rosemary F, Galella, Michael, Pitt, Sidney, Shen, Guoxiang, Fura, Aberra, Gillooly, Kathleen, McIntyre, Kim W, Tang, Vicky, Tokarski, John, Sack, John S, Khan, Javed, Carter, Percy H, Barrish, Joel C, Nadler, Steven G, Salter-Cid, Luisa M, Schieven, Gary L, Wrobleski, Stephen T, Pitts, William J

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Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors von Duan, James J-W, Lu, Zhonghui, Jiang, Bin, Yang, Bingwei V, Doweyko, Lidia M, Nirschl, David S, Haque, Lauren E, Lin, Shuqun, Brown, Gregory, Hynes, Jr, John, Tokarski, John S, Sack, John S, Khan, Javed, Lippy, Jonathan S, Zhang, Rosemary F, Pitt, Sidney, Shen, Guoxiang, Pitts, William J, Carter, Percy H, Barrish, Joel C, Nadler, Steven G, Salter-Cid, Luisa M, McKinnon, Murray, Fura, Aberra, Schieven, Gary L, Wrobleski, Stephen T

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Rapid Compound Integrity Assessment for High-Throughput Screening Hit Triaging von Shou, Wilson Z., Gerritz, Samuel W., Harden, David, Lawrence, R. Michael, Chase, Peter, Chin, Jefferson, Surti, Neha, Lippy, Jonathan S., Weller, Harold N., Nielsen, Julia, Weerakoon, Darshani

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A Scintillation Proximity Assay for RNA Detection von Liu, Jianwei, Feldman, Patricia A., Lippy, Jonathan S., Bobkova, Ekaterina, Kurilla, Michael G., Chung, Thomas D.Y.

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Identification of 2-amino-5-(thioaryl)thiazoles as inhibitors of nerve growth factor receptor TrkA von Kim, Soong-Hoon, Tokarski, John S., Leavitt, Kenneth J., Fink, Brian E., Salvati, Mark E., Moquin, Robert, Obermeier, Mary T., Trainor, George L., Vite, Gregory G., Stadnick, Linda K., Lippy, Jonathan S., You, Dan, Lorenzi, Matthew V., Chen, Ping

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Quantitative, High-Throughput Cell-Based Assays for Inhibitors of trkA Receptor von Angeles, Thelma S., Lippy, Jonathan S., Yang, Shi X.

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Latent demand for the bone-anchored hearing aid: the Lippy Group experience von Burkey, John M, Berenholz, Leonard P, Lippy, William H

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TiN Metal Hard Mask Removal with Selectivity to Tungsten and TiN Liner von Lippy, Steven, Chen, Li-Min, Peethala, Brown, Rath, David L, Boggs, Karl, Sankarapandian, Muthumanickam, Kennedy, Evelyn

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Total Ossiculoplasty: Advantages of Two-Point Stabilization Technique von Berenholz, Leonard, Burkey, John, Lippy, William

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Abstract 5395: Anti-tumor activity of BMS-595, a novel CK2 kinase inhibitor von Rupnow, Brent A., Yu, Chiang, Pabalan, Jonathan G., Roongta, Urvashi V., Lippy, Jonathan S., Dongre, Ashok R., Obermeier, Mary T., Fura, Aberra, Elzinga, Paul A., Henley, Benjamin J., Fargnoli, Joseph, Lee, Francis Y., Foster, William R., Tarby, Christine M., Fink, Brian E., Tokarski, John S., Gavai, Ashvinikumar V., Wong, Tai W., Hunt, John T., Vite, Gregory D., Purandare, Ashok V.

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Cleaning Options for Copper/Ultralow-k Structures von Hsu, C P S, Cruz, B, Lippy, S, Stewart, J

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Crosslinked polyolefin foam sheet with exceptional softness, haptics, moldability, thermal stability and shear strength von Lippy, Jeffrey S, Baldwin, Jesse J, Sieradzki, Pawel

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