Rule of five in 2015 and beyond: Target and ligand structural limitations, ligand chemistry structure and drug discovery project decisions von Lipinski, Christopher A.

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings von Lipinski, Christopher A., Lombardo, Franco, Dominy, Beryl W., Feeney, Paul J.

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Lead- and drug-like compounds: the rule-of-five revolution von Lipinski, Christopher A.

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Navigating chemical space for biology and medicine von Lipinski, Christopher, Hopkins, Andrew

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Phenotypic screening of low molecular weight compounds is rich ground for repurposed, on-target drugs von Lipinski, Christopher A., Reaume, Andrew G.

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High throughput in vivo phenotypic screening for drug repurposing: Discovery of MLR-1023 a novel insulin sensitizer and novel Lyn kinase activator with clinical proof of concept von Lipinski, Christopher A., Reaume, Andrew G.

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The rule of five should not impede anti-parasitic drug development von McKerrow, James H., Lipinski, Christopher A.

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings von Lipinski, Christopher A, Lombardo, Franco, Dominy, Beryl W, Feeney, Paul J

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Thermodynamic Proxies to Compensate for Biases in Drug Discovery Methods von Ekins, Sean, Litterman, Nadia K., Lipinski, Christopher A., Bunin, Barry A.

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Parallel worlds of public and commercial bioactive chemistry data von Lipinski, Christopher A, Litterman, Nadia K, Southan, Christopher, Williams, Antony J, Clark, Alex M, Ekins, Sean

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Badapple: promiscuity patterns from noisy evidence von Yang, Jeremy J., Ursu, Oleg, Lipinski, Christopher A., Sklar, Larry A., Oprea, Tudor I., Bologa, Cristian G.

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings von Lipinski, Christopher A., Lombardo, Franco, Dominy, Beryl W., Feeney, Paul J.

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Computational Prediction and Validation of an Expert’s Evaluation of Chemical Probes von Litterman, Nadia K, Lipinski, Christopher A, Bunin, Barry A, Ekins, Sean

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Emergency Department Rotational Patient Assignment von Traub, Stephen J., MD, Stewart, Christopher F., MD, Didehban, Roshanak, MS, Bartley, Adam C., MS, Saghafian, Soroush, PhD, Smith, Vernon D., MD, Silvers, Scott M., MD, LeCheminant, Ryan, BS, Lipinski, Christopher A., MD

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Emergency Department Rapid Medical Assessment: Overall Effect and Mechanistic Considerations von Traub, Stephen J., MD, Wood, Joseph P., MD, Kelley, James, MD, Nestler, David M., MD, Chang, Yu-Hui, PhD, Saghafian, Soroush, PhD, Lipinski, Christopher A., MD

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Physician in Triage Versus Rotational Patient Assignment von Traub, Stephen J., MD, Bartley, Adam C., MS, Smith, Vernon D., MD, Didehban, Roshanak, MS, Lipinski, Christopher A., MD, Saghafian, Soroush, PhD

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Serum Lactate and Mortality in Emergency Department Patients with Cancer von Maher, Steven A, Temkit, M'hamed, Buras, Matthew R, McLemore, Ryan Y, Butler, Rebecca K, Chowdhury, Yasmynn, Lipinski, Christopher A, Traub, Stephen J

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Chris Lipinski discusses life and chemistry after the Rule of Five von Owens, Joanna

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A crowdsourcing evaluation of the NIH chemical probes von Oprea, Tudor I, Sklar, Larry A, Bologa, Cristian G, Boyer, Scott, Curpan, Ramona F, Glen, Robert C, Hopkins, Andrew L, Lipinski, Christopher A, Marshall, Garland R, Martin, Yvonne C, Ostopovici-Halip, Liliana, Rishton, Gilbert, Ursu, Oleg, Vaz, Roy J, Waller, Chris, Waldmann, Herbert

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The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose homeostasis in animal models of type 2 diabe... von Ochman, Alexander R, Lipinski, Christopher A, Handler, Jeffrey A, Reaume, Andrew G, Saporito, Michael S

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