The Courage study: A first-in-human phase 1 study of the CBP/p300 inhibitor FT-7051 in men with metastatic castration-resistant prostate cancer von Armstrong, Andrew J., Gordon, Michael S., Reimers, Melissa Andrea, Sedkov, Alex, Lipford, Kate, Snavely-Merhaut, Juliana, Kumar, Sonia, Guichard, Sylvie Mireille, Shore, Neal

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A phase Ib/II study of olutasidenib in patients with relapsed/refractory IDH1 mutant gliomas: Safety and efficacy as single agent and in combination with azacitidine von De La Fuente, Macarena Ines, Colman, Howard, Rosenthal, Mark, Van Tine, Brian Andrew, Levaci, Danijela, Walbert, Tobias, Gan, Hui Kong, Vieito, Maria, Milhem, Mohammed M., Lipford, Kate, Forsyth, Sanjeev, Guichard, Sylvie Mireille, Mikhailov, Yelena, Sedkov, Alexander, Thomson, Blythe, Kelly, Patrick Francis, Monga, Varun

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A phase Ib/II study of olutasidenib in patients with relapsed/refractory IDH1 mutant solid tumors: Safety and efficacy as single agent von Jones, Robin Lewis, Macarulla, Teresa, Charlson, John A., Van Tine, Brian Andrew, Goyal, Lipika, Italiano, Antoine, Massard, Christophe, Rosenthal, Mark, De La Fuente, Macarena Ines, Roxburgh, Patricia, Kundranda, Madappa N., Blay, Jean-Yves, Yoo, Changhoon, Lipford, Kate, Forsyth, Sanjeev, Guichard, Sylvie Mireille, Mikhailov, Yelena, Thomson, Blythe, Kelly, Patrick Francis, Duffaud, Florence

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ACTR-52. PHASE 1 STUDY OF FT-2102, AN INHIBITOR OF MUTANT IDH1, IN PATIENTS WITH RELAPSED/REFRACTORY IDH1 MUTANT GLIOMAS: PRELIMINARY SAFETY AND CLINICAL ACTIVITY von De la Fuente, Macarena I, Colman, Howard, Rosenthal, Mark, Van Tine, Brian A, Fonkem, Ekokobe, Walbert, Tobias, Milhem, Mohammed, Lipford, Kate, Forsyth, Sanjeev, Guichard, Sylvie, Brevard, Julie, Mikhailov, Yelena, Thomson, Blythe, Monga, Varun

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Discovery of a Covalent Inhibitor of KRAS(G12C) (AMG 510) for the Treatment of Solid Tumors von Lanman, Brian A., Allen, Jennifer R., Allen, John G., Amegadzie, Albert K., Ashton, Kate S., Booker, Shon K., Chen, Jian Jeffrey, Chen, Ning, Frohn, Michael J., Goodman, Guy, Kopecky, David J., Liu, Longbin, Lopez, Patricia, Low, Jonathan D., Ma, Vu, Minatti, Ana E., Nguyen, Thomas T., Nishimura, Nobuko, Pickrell, Alexander J., Reed, Anthony B., Shin, Youngsook, Siegmund, Aaron C., Tamayo, Nuria A., Tegley, Christopher M., Walton, Mary C., Wang, Hui-Ling, Wurz, Ryan P., Xue, May, Yang, Kevin C., Achanta, Pragathi, Bartberger, Michael D., Canon, Jude, Hollis, L. Steven, McCarter, John D., Mohr, Christopher, Rex, Karen, Saiki, Anne Y., San Miguel, Tisha, Volak, Laurie P., Wang, Kevin H., Whittington, Douglas A., Zech, Stephan G., Lipford, J. Russell, Cee, Victor J.

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Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases von Luo, Xin, Archibeque, Ivonne, Dellamaggiore, Ken, Smither, Kate, Homann, Oliver, Lipford, James Russell, Mohl, Dane

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Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors von Lanman, Brian A, Allen, Jennifer R, Allen, John G, Amegadzie, Albert K, Ashton, Kate S, Booker, Shon K, Chen, Jian Jeffrey, Chen, Ning, Frohn, Michael J, Goodman, Guy, Kopecky, David J, Liu, Longbin, Lopez, Patricia, Low, Jonathan D, Ma, Vu, Minatti, Ana E, Nguyen, Thomas T, Nishimura, Nobuko, Pickrell, Alexander J, Reed, Anthony B, Shin, Youngsook, Siegmund, Aaron C, Tamayo, Nuria A, Tegley, Christopher M, Walton, Mary C, Wang, Hui-Ling, Wurz, Ryan P, Xue, May, Yang, Kevin C, Achanta, Pragathi, Bartberger, Michael D, Canon, Jude, Hollis, L. Steven, McCarter, John D, Mohr, Christopher, Rex, Karen, Saiki, Anne Y, San Miguel, Tisha, Volak, Laurie P, Wang, Kevin H, Whittington, Douglas A, Zech, Stephan G, Lipford, J. Russell, Cee, Victor J

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Discovery of a Covalent Inhibitor of KRAS G12C (AMG 510) for the Treatment of Solid Tumors von Lanman, Brian A, Allen, Jennifer R, Allen, John G, Amegadzie, Albert K, Ashton, Kate S, Booker, Shon K, Chen, Jian Jeffrey, Chen, Ning, Frohn, Michael J, Goodman, Guy, Kopecky, David J, Liu, Longbin, Lopez, Patricia, Low, Jonathan D, Ma, Vu, Minatti, Ana E, Nguyen, Thomas T, Nishimura, Nobuko, Pickrell, Alexander J, Reed, Anthony B, Shin, Youngsook, Siegmund, Aaron C, Tamayo, Nuria A, Tegley, Christopher M, Walton, Mary C, Wang, Hui-Ling, Wurz, Ryan P, Xue, May, Yang, Kevin C, Achanta, Pragathi, Bartberger, Michael D, Canon, Jude, Hollis, L Steven, McCarter, John D, Mohr, Christopher, Rex, Karen, Saiki, Anne Y, San Miguel, Tisha, Volak, Laurie P, Wang, Kevin H, Whittington, Douglas A, Zech, Stephan G, Lipford, J Russell, Cee, Victor J

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