Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function von Pobezinsky, Leonid A, Etzensperger, Ruth, Jeurling, Susanna, Alag, Amala, Kadakia, Tejas, McCaughtry, Tom M, Kimura, Motoko Y, Sharrow, Susan O, Guinter, Terry I, Feigenbaum, Lionel, Singer, Alfred

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Uromodulin p.Cys147Trp mutation drives kidney disease by activating ER stress and apoptosis von Johnson, Bryce G, Dang, Lan T, Marsh, Graham, Roach, Allie M, Levine, Zebulon G, Monti, Anthony, Reyon, Deepak, Feigenbaum, Lionel, Duffield, Jeremy S

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Control of Toll-like Receptor 7 Expression Is Essential to Restrict Autoimmunity and Dendritic Cell Proliferation von Deane, Jonathan A., Pisitkun, Prapaporn, Barrett, Rebecca S., Feigenbaum, Lionel, Town, Terrence, Ward, Jerrold M., Flavell, Richard A., Bolland, Silvia

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Tumor-specific Th17-polarized cells eradicate large established melanoma von Muranski, Pawel, Boni, Andrea, Antony, Paul A., Cassard, Lydie, Irvine, Kari R., Kaiser, Andrew, Paulos, Chrystal M., Palmer, Douglas C., Touloukian, Christopher E., Ptak, Krzysztof, Gattinoni, Luca, Wrzesinski, Claudia, Hinrichs, Christian S., Kerstann, Keith W., Feigenbaum, Lionel, Chan, Chi-Chao, Restifo, Nicholas P.

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Global Regulation of Promoter Melting in Naive Lymphocytes von Kouzine, Fedor, Wojtowicz, Damian, Yamane, Arito, Resch, Wolfgang, Kieffer-Kwon, Kyong-Rim, Bandle, Russell, Nelson, Steevenson, Nakahashi, Hirotaka, Awasthi, Parirokh, Feigenbaum, Lionel, Menoni, Herve, Hoeijmakers, Jan, Vermeulen, Wim, Ge, Hui, Przytycka, Teresa M., Levens, David, Casellas, Rafael

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NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells von Masters, Seth L., Gerlic, Motti, Metcalf, Donald, Preston, Simon, Pellegrini, Marc, O’Donnell, Joanne A., McArthur, Kate, Baldwin, Tracey M., Chevrier, Stephane, Nowell, Cameron J., Cengia, Louise H., Henley, Katya J., Collinge, Janelle E., Kastner, Daniel L., Feigenbaum, Lionel, Hilton, Douglas J., Alexander, Warren S., Kile, Benjamin T., Croker, Ben A.

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CtIP-mediated resection is essential for viability and can operate independently of BRCA1 von Polato, Federica, Callen, Elsa, Wong, Nancy, Faryabi, Robert, Bunting, Samuel, Chen, Hua-Tang, Kozak, Marina, Kruhlak, Michael J, Reczek, Colleen R, Lee, Wen-Hwa, Ludwig, Thomas, Baer, Richard, Feigenbaum, Lionel, Jackson, Stephen, Nussenzweig, André

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Ifih1 gene dose effect reveals MDA5-mediated chronic type I IFN gene signature, viral resistance, and accelerated autoimmunity von Crampton, Steve P, Deane, Jonathan A, Feigenbaum, Lionel, Bolland, Silvia

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Regulation of AID expression in the immune response von Crouch, Elizabeth E, Li, Zhiyu, Takizawa, Makiko, Fichtner-Feigl, Stefan, Gourzi, Polyxeni, Montaño, Carolina, Feigenbaum, Lionel, Wilson, Patrick, Janz, Siegfried, Papavasiliou, F Nina, Casellas, Rafael

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The transcription factor ThPOK suppresses Runx3 and imposes CD4+ lineage fate by inducing the SOCS suppressors of cytokine signaling von Luckey, Megan A, Kimura, Motoko Y, Waickman, Adam T, Feigenbaum, Lionel, Singer, Alfred, Park, Jung-Hyun

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A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3 von Steward-Tharp, Scott M., Laurence, Arian, Kanno, Yuka, Kotlyar, Alex, Villarino, Alejandro V., Sciume, Giuseppe, Kuchen, Stefan, Resch, Wolfgang, Wohlfert, Elizabeth A., Jiang, Kan, Hirahara, Kiyoshi, Vahedi, Golnaz, Sun, Hong-wei, Feigenbaum, Lionel, Milner, Joshua D., Holland, Steven M., Casellas, Rafael, Powrie, Fiona, O'Shea, John J.

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Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein von Rane, Neena S, Chakrabarti, Oishee, Feigenbaum, Lionel, Hegde, Ramanujan S

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Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo von Wang, Weidong, Pellegrini, Manuela, Feigenbaum, Lionel, Celeste, Arkady, Guo, Rong, Nussenzweig, André, Difilippantonio, Simone

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Visualizing the Selectivity and Dynamics of Interferon Signaling In Vivo von Stifter, Sebastian A., Bhattacharyya, Nayan, Sawyer, Andrew J., Cootes, Taylor A., Stambas, John, Doyle, Sean E., Feigenbaum, Lionel, Paul, William E., Britton, Warwick J., Sher, Alan, Feng, Carl G.

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Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain von PALMIERI, Diane, BRONDER, Julie L, VORTMEYER, Alexander O, STEINBERG, Seth M, ALDAPE, Kenneth, STEEG, Patricia S, HERRING, Jeanne M, YONEDA, Toshiyuki, WEIL, Robert J, STARK, Andreas M, KUREK, Raffael, VEGA-VALLE, Eleazar, FEIGENBAUM, Lionel, HALVERSON, Douglas

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Reduced Translocation of Nascent Prion Protein During ER Stress Contributes to Neurodegeneration von Rane, Neena S., Kang, Sang-Wook, Chakrabarti, Oishee, Feigenbaum, Lionel, Hegde, Ramanujan S.

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Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15Rα von Chen, Jing, Feigenbaum, Lionel, Awasthi, Parirokh, Butcher, Donna O., Anver, Miriam R., Golubeva, Yelena G., Bamford, Richard, Zhang, Xiaojie, St. Claire, Mark B., Thomas, Craig J., Discepolo, Valentina, Jabri, Bana, Waldmann, Thomas A.

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AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development von Takizawa, Makiko, Tolarová, Helena, Li, Zhiyu, Dubois, Wendy, Lim, Susan, Callen, Elsa, Franco, Sonia, Mosaico, Maria, Feigenbaum, Lionel, Alt, Frederick W, Nussenzweig, André, Potter, Michael, Casellas, Rafael

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Smad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2 von Yang, Yu-An, Zhang, Gen-Mu, Feigenbaum, Lionel, Zhang, Ying E.

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Expression of the SNARE protein SNAP-23 is essential for cell survival von Kaul, Sunil, Mittal, Sharad K, Feigenbaum, Lionel, Kruhlak, Michael J, Roche, Paul A

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