Molecular tuning of farnesoid X receptor partial agonism von Merk, Daniel, Sreeramulu, Sridhar, Kudlinzki, Denis, Saxena, Krishna, Linhard, Verena, Gande, Santosh L., Hiller, Fabian, Lamers, Christina, Nilsson, Ewa, Aagaard, Anna, Wissler, Lisa, Dekker, Niek, Bamberg, Krister, Schubert-Zsilavecz, Manfred, Schwalbe, Harald

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Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs von Heinzlmeir, Stephanie, Kudlinzki, Denis, Sreeramulu, Sridhar, Klaeger, Susan, Gande, Santosh Lakshmi, Linhard, Verena, Wilhelm, Mathias, Qiao, Huichao, Helm, Dominic, Ruprecht, Benjamin, Saxena, Krishna, Médard, Guillaume, Schwalbe, Harald, Kuster, Bernhard

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High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus von Kudlinzki, Denis, Linhard, Verena L., Saxena, Krishna, Sreeramulu, Sridhar, Gande, Santosh, Schieborr, Ulrich, Dreyer, Matthias, Schwalbe, Harald

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The MECP2‐TRD domain interacts with the DNMT3A‐ADD domain at the H3‐tail binding site von Kunert, Stefan, Linhard, Verena, Weirich, Sara, Choudalakis, Michel, Osswald, Florian, Krämer, Lisa, Köhler, Anja R., Bröhm, Alexander, Wollenhaupt, Jan, Schwalbe, Harald, Jeltsch, Albert

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Cover Feature: Optimization of the Lead Compound NVP‐BHG712 as a Colorectal Cancer Inhibitor (Chem. Eur. J. 23/2023) von Tröster, Alix, DiPrima, Michael, Jores, Nathalie, Kudlinzki, Denis, Sreeramulu, Sridhar, Gande, Santosh L., Linhard, Verena, Ludig, Damian, Schug, Alexander, Saxena, Krishna, Reinecke, Maria, Heinzlmeir, Stephanie, Leisegang, Matthias S., Wollenhaupt, Jan, Lennartz, Frank, Weiss, Manfred S., Kuster, Bernhard, Tosato, Giovanna, Schwalbe, Harald

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Modulation of Aβ42 Aggregation Kinetics and Pathway by Low‐Molecular‐Weight Inhibitors von Hutchison, Marie‐Theres, Bellomo, Giovanni, Cherepanov, Alexey, Stirnal, Elke, Fürtig, Boris, Richter, Christian, Linhard, Verena, Gurewitsch, Elina, Lelli, Moreno, Morgner, Nina, Schrader, Thomas, Schwalbe, Harald

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Randomizing the Unfolded State of Peptides (and Proteins) by Nearest Neighbor Interactions between Unlike Residues von Toal, Siobhan E., Kubatova, Nina, Richter, Christian, Linhard, Verena, Schwalbe, Harald, Schweitzer-Stenner, Reinhard

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Optimization of the Lead Compound NVP‐BHG712 as a Colorectal Cancer Inhibitor von Tröster, Alix, DiPrima, Michael, Jores, Nathalie, Kudlinzki, Denis, Sreeramulu, Sridhar, Gande, Santosh L., Linhard, Verena, Ludig, Damian, Schug, Alexander, Saxena, Krishna, Reinecke, Maria, Heinzlmeir, Stephanie, Leisegang, Matthias S., Wollenhaupt, Jan, Lennartz, Frank, Weiss, Manfred S., Kuster, Bernhard, Tosato, Giovanna, Schwalbe, Harald

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Binding Adaptation of GS-441524 Diversifies Macro Domains and Downregulates SARS-CoV-2 de-MARylation Capacity von Tsika, Aikaterini C., Gallo, Angelo, Fourkiotis, Nikolaos K., Argyriou, Aikaterini I., Sreeramulu, Sridhar, Löhr, Frank, Rogov, Vladimir V., Richter, Christian, Linhard, Verena, Gande, Santosh L., Altincekic, Nadide, Krishnathas, Robin, Elamri, Isam, Schwalbe, Harald, Wollenhaupt, Jan, Weiss, Manfred S., Spyroulias, Georgios A.

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Mechanistic Impact of Different Ligand Scaffolds on FXR Modulation Suggests Avenues to Selective Modulators von Heering, Jan, Jores, Nathalie, Kilu, Whitney, Schallmayer, Espen, Peelen, Evelyn, Muehler, Andreas, Kohlhof, Hella, Vitt, Daniel, Linhard, Verena, Gande, Santosh L., Chaikuad, Apirat, Sreeramulu, Sridhar, Schwalbe, Harald, Merk, Daniel

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Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily von Ma, Xueyan, Koepke, Juergen, Bayer, Anja, Linhard, Verena, Fritzsch, Günter, Zhang, Bin, Michel, Hartmut, Stöckigt, Joachim

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Corrigendum: Randomizing the Unfolded State of Peptides (and Proteins) by Nearest Neighbor Interactions between Unlike Residues von Toal, Siobhan E., Kubatova, Nina, Richter, Christian, Linhard, Verena, Schwalbe, Harald, Schweitzer‐Stenner, Reinhard

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The domain architecture of PtkA, the first tyrosine kinase from Mycobacterium tuberculosis, differs from the conventional kinase architecture von Niesteruk, Anna, Jonker, Hendrik R.A., Richter, Christian, Linhard, Verena, Sreeramulu, Sridhar, Schwalbe, Harald

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Chemoproteomics‐Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors von Heinzlmeir, Stephanie, Lohse, Jonas, Treiber, Tobias, Kudlinzki, Denis, Linhard, Verena, Gande, Santosh Lakshmi, Sreeramulu, Sridhar, Saxena, Krishna, Liu, Xiaofeng, Wilhelm, Mathias, Schwalbe, Harald, Kuster, Bernhard, Médard, Guillaume

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Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies von Altincekic, Nadide, Jores, Nathalie, Löhr, Frank, Richter, Christian, Ehrhardt, Claus, Blommers, Marcel J. J., Berg, Hannes, Öztürk, Sare, Gande, Santosh L., Linhard, Verena, Orts, Julien, Abi Saad, Marie Jose, Bütikofer, Matthias, Kaderli, Janina, Karlsson, B. Göran, Brath, Ulrika, Hedenström, Mattias, Gröbner, Gerhard, Sauer, Uwe H., Perrakis, Anastassis, Langer, Julian, Banci, Lucia, Cantini, Francesca, Fragai, Marco, Grifagni, Deborah, Barthel, Tatjana, Wollenhaupt, Jan, Weiss, Manfred S., Robertson, Angus, Bax, Adriaan, Sreeramulu, Sridhar, Schwalbe, Harald

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NVP‐BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family von Tröster, Alix, Heinzlmeir, Stephanie, Berger, Benedict‐Tilman, Gande, Santosh L., Saxena, Krishna, Sreeramulu, Sridhar, Linhard, Verena, Nasiri, Amir H., Bolte, Michael, Müller, Susanne, Kuster, Bernhard, Médard, Guillaume, Kudlinzki, Denis, Schwalbe, Harald

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Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina von Chatterjee, Deep, Kudlinzki, Denis, Linhard, Verena, Saxena, Krishna, Schieborr, Ulrich, Gande, Santosh L., Wurm, Jan Philip, Wöhnert, Jens, Abele, Rupert, Rogov, Vladimir V., Dötsch, Volker, Osiewacz, Heinz D., Sreeramulu, Sridhar, Schwalbe, Harald

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On the Implication of Water on Fragment‐to‐Ligand Growth in Kinase Binding Thermodynamics von Wienen‐Schmidt, Barbara, Wulsdorf, Tobias, Jonker, Hendrik R. A., Saxena, Krishna, Kudlinzki, Denis, Linhard, Verena, Sreeramulu, Sridhar, Heine, Andreas, Schwalbe, Harald, Klebe, Gerhard

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Expression and Purification of EPHA2 Tyrosine Kinase Domain for Crystallographic and NMR Studies von Gande, Santosh L., Saxena, Krishna, Sreeramulu, Sridhar, Linhard, Verena, Kudlinzki, Denis, Heinzlmeir, Stephanie, Reichert, Andreas J., Skerra, Arne, Kuster, Bernhard, Schwalbe, Harald

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Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications von Altincekic, Nadide, Korn, Sophie Marianne, Qureshi, Nusrat Shahin, Dujardin, Marie, Ninot-Pedrosa, Marti, Abele, Rupert, Saad, Marie Jose Abi, Alfano, Caterina, Almeida, Fabio C. L., Alshamleh, Islam, de Amorim, Gisele Cardoso, Anderson, Thomas K., Anobom, Cristiane D., Anorma, Chelsea, Bains, Jasleen Kaur, Bax, Adriaan, Blackledge, Martin, Blechar, Julius, Bockmann, Anja, Brigandat, Louis, Bula, Anna, Buetikofer, Matthias, Camacho-Zarco, Aldo R., Carlomagno, Teresa, Caruso, Icaro Putinhon, Ceylan, Betul, Chaikuad, Apirat, Chu, Feixia, Cole, Laura, Crosby, Marquise G., de Jesus, Vanessa, Dhamotharan, Karthikeyan, Felli, Isabella C., Ferner, Jan, Fleischmann, Yanick, Fogeron, Marie-Laure, Fourkiotis, Nikolaos K., Fuks, Christin, Fuertig, Boris, Gallo, Angelo, Gande, Santosh L., Gerez, Juan Atilio, Ghosh, Dhiman, Gomes-Neto, Francisco, Gorbatyuk, Oksana, Guseva, Serafima, Hacker, Carolin, Haefner, Sabine, Hao, Bing, Hargittay, Bruno, Henzler-Wildman, K., Hoch, Jeffrey C., Hohmann, Katharina F., Hutchison, Marie T., Jaudzems, Kristaps, Jovic, Katarina, Kaderli, Janina, Kalnins, Gints, Kanepe, Iveta, Kirchdoerfer, Robert N., Kirkpatrick, John, Knapp, Stefan, Krishnathas, Robin, Kutz, Felicitas, zur Lage, Susanne, Lambertz, Roderick, Lang, Andras, Laurents, Douglas, Lecoq, Lauriane, Linhard, Verena, Loehr, Frank, Malki, Anas, Bessa, Luiza Mamigonian, Martin, Rachel W., Matzel, Tobias, Maurin, Damien, McNutt, Seth W., Mebus-Antunes, Nathane Cunha, Meier, Beat H., Meiser, Nathalie, Mompean, Miguel, Monaca, Elisa, Montserret, Roland, Perez, Laura Marino, Moser, Celine, Muhle-Goll, Claudia, Neves-Martins, Thais Cristtina, Ni, Xiamonin, Norton-Baker, Brenna, Pierattelli, Roberta, Pontoriero, Letizia, Pustovalova, Yulia, Ohlenschlaeger, Oliver, Orts, Julien, Da Poian, Andrea T., Pyper, Dennis J., Richter, Christian, Riek, Roland, Rienstra, Chad M., Robertson, Angus

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