Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease von Fil, Daniel, DeLoach, Abigail, Yadav, Shilpi, Alkam, Duah, MacNicol, Melanie, Singh, Awantika, Compadre, Cesar M, Goellner, Joseph J, O'Brien, Charles A, Fahmi, Tariq, Basnakian, Alexei G, Calingasan, Noel Y, Klessner, Jodi L, Beal, Flint M, Peters, Owen M, Metterville, Jake, Brown, Jr, Robert H, Ling, Karen K Y, Rigo, Frank, Ozdinler, P Hande, Kiaei, Mahmoud

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TSUNAMI: an antisense method to phenocopy splicing-associated diseases in animals von Sahashi, Kentaro, Hua, Yimin, Ling, Karen K Y, Hung, Gene, Rigo, Frank, Horev, Guy, Katsuno, Masahisa, Sobue, Gen, Ko, Chien-Ping, Bennett, C Frank, Krainer, Adrian R

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Minor snRNA gene delivery improves the loss of proprioceptive synapses on SMA motor neurons von Osman, Erkan Y., Van Alstyne, Meaghan, Yen, Pei-Fen, Lotti, Francesco, Feng, Zhihua, Ling, Karen K.Y., Ko, Chien-Ping, Pellizzoni, Livio, Lorson, Christian L.

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SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy von Naryshkin, Nikolai A., Weetall, Marla, Dakka, Amal, Narasimhan, Jana, Zhao, Xin, Feng, Zhihua, Ling, Karen K. Y., Karp, Gary M., Qi, Hongyan, Woll, Matthew G., Chen, Guangming, Zhang, Nanjing, Gabbeta, Vijayalakshmi, Vazirani, Priya, Bhattacharyya, Anuradha, Furia, Bansri, Risher, Nicole, Sheedy, Josephine, Kong, Ronald, Ma, Jiyuan, Turpoff, Anthony, Lee, Chang-Sun, Zhang, Xiaoyan, Moon, Young-Choon, Trifillis, Panayiota, Welch, Ellen M., Colacino, Joseph M., Babiak, John, Almstead, Neil G., Peltz, Stuart W., Eng, Loren A., Chen, Karen S., Mull, Jesse L., Lynes, Maureen S., Rubin, Lee L., Fontoura, Paulo, Santarelli, Luca, Haehnke, Daniel, McCarthy, Kathleen D., Schmucki, Roland, Ebeling, Martin, Sivaramakrishnan, Manaswini, Ko, Chien-Ping, Paushkin, Sergey V., Ratni, Hasane, Gerlach, Irene, Ghosh, Anirvan, Metzger, Friedrich

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Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy von Ling, Karen K. Y., Gibbs, Rebecca M., Feng, Zhihua, Ko, Chien-Ping

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Synaptic defects in the spinal and neuromuscular circuitry in a mouse model of spinal muscular atrophy von Ling, Karen K Y, Lin, Ming-Yi, Zingg, Brian, Feng, Zhihua, Ko, Chien-Ping

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Pharmacologically induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset von Feng, Zhihua, Ling, Karen K Y, Zhao, Xin, Zhou, Chunyi, Karp, Gary, Welch, Ellen M, Naryshkin, Nikolai, Ratni, Hasane, Chen, Karen S, Metzger, Friedrich, Paushkin, Sergey, Weetall, Marla, Ko, Chien-Ping

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SMN protein is required throughout life to prevent spinal muscular atrophy disease progression von Zhao, Xin, Feng, Zhihua, Risher, Nicole, Mollin, Anna, Sheedy, Josephine, Ling, Karen K Y, Narasimhan, Jana, Dakka, Amal, Baird, John D, Ratni, Hasane, Lutz, Catherine, Chen, Karen S, Naryshkin, Nikolai A, Ko, Chien-Ping, Welch, Ellen, Metzger, Friedrich, Weetall, Marla

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Pharmacokinetics, pharmacodynamics, and efficacy of a small-molecule SMN2 splicing modifier in mouse models of spinal muscular atrophy von Zhao, Xin, Feng, Zhihua, Ling, Karen K Y, Mollin, Anna, Sheedy, Josephine, Yeh, Shirley, Petruska, Janet, Narasimhan, Jana, Dakka, Amal, Welch, Ellen M, Karp, Gary, Chen, Karen S, Metzger, Friedrich, Ratni, Hasane, Lotti, Francesco, Tisdale, Sarah, Naryshkin, Nikolai A, Pellizzoni, Livio, Paushkin, Sergey, Ko, Chien-Ping, Weetall, Marla

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Minor snRNA gene delivery improves the loss of proprioceptive synapses on SMA motor neurons von Osman, Erkan Y., Van Alstyne, Meaghan, Yen, Pei-Fen, Lotti, Francesco, Feng, Zhihua, Ling, Karen K. Y., Ko, Chien-Ping, Pellizzoni, Livio, Lorson, Christian L.

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Pathological impact of SMN2 mis‐splicing in adult SMA mice von Sahashi, Kentaro, Ling, Karen K. Y., Hua, Yimin, Wilkinson, John Erby, Nomakuchi, Tomoki, Rigo, Frank, Hung, Gene, Xu, David, Jiang, Ya‐Ping, Lin, Richard Z., Ko, Chien‐Ping, Bennett, C. Frank, Krainer, Adrian R.

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ATP Acts via P2Y1 Receptors to Stimulate Acetylcholinesterase and Acetylcholine Receptor Expression: Transduction and Transcription Control von Choi, Roy C. Y, Siow, Nina L, Cheng, Anthony W. M, Ling, Karen K. Y, Tung, Edmund K. K, Simon, Joseph, Barnard, Eric A, Tsim, Karl W. K

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P2Y2 Receptor Activation Regulates the Expression of Acetylcholinesterase and Acetylcholine Receptor Genes at Vertebrate Neuromuscular Junctions von Tung, Edmund K K, Choi, Roy C Y, Siow, Nina L, Jiang, Joy X S, Ling, Karen K Y, Simon, Joseph, Barnard, Eric A, Tsim, Karl W K

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ATP potentiates the formation of AChR aggregate in the co-culture of NG108-15 cells with C2C12 myotubes von Ling, Karen K.Y., Siow, Nina L., Choi, Roy C.Y., Tsim, Karl W.K.

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ATP potentiates agrin-induced AChR aggregation in cultured myotubes: activation of RhoA in P2Y1 nucleotide receptor signaling at vertebrate neuromuscular junctions von Ling, Karen K Y, Siow, Nina L, Choi, Roy C Y, Ting, Annie K L, Kong, Ling W, Tsim, Karl W K

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ATP Potentiates Agrin-induced AChR Aggregation in Cultured Myotubes von Ling, Karen K.Y., Siow, Nina L., Choi, Roy C.Y., Ting, Annie K.L., Kong, Ling W., Tsim, Karl W.K.

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Transcriptional control of different acetylcholinesterase subunits in formation and maintenance of vertebrate neuromuscular junctions von Tsim, Karl W K, Xie, Heidi Q H, Ting, Annie K L, Siow, Nina L, Ling, Karen K Y, Kong, Ling W

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Bridge centrality network structure of negative symptoms in people with schizophrenia von Wang, Ling-ling, Tam, Michelle H. W., Ho, Karen K. Y., Hung, Karen S. Y., Wong, Jessica O. Y., Lui, Simon S. Y., Chan, Raymond C. K.

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Emotion-behaviour decoupling and experiential pleasure deficits predict negative symptoms and functional outcome in first-episode schizophrenia patients von Lui, Simon S.Y., Wang, Ling-ling, Lau, Wilson Y.S., Shing, Eunice, Yeung, Hera K.H., Tsang, Kirby C.M., Zhan, Emma N., Cheung, Ezmond S.L., Ho, Karen K.Y., Hung, Karen S.Y., Cheung, Eric F.C., Chan, Raymond C.K.

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Long-term Cost-effectiveness in the Veterans Affairs Open vs Endovascular Repair Study of Aortic Abdominal Aneurysm: A Randomized Clinical Trial von Lederle, Frank A, Stroupe, Kevin T, Kyriakides, Tassos C, Ge, Ling, Freischlag, Julie A

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