Morphological and sensorimotor phenotypes in a zebrafish CHARGE syndrome model are domain‐dependent von Hodorovich, Dana R., Lindsley, Patrick M., Berry, Austen A., Burton, Derek F., Marsden, Kurt C.

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Healthcare personnel exposure in an emergency department during influenza season von Rule, Ana M, Apau, Otis, Ahrenholz, Steven H, Brueck, Scott E, Lindsley, William G, de Perio, Marie A, Noti, John D, Shaffer, Ronald E, Rothman, Richard, Grigorovitch, Alina, Noorbakhsh, Bahar, Beezhold, Donald H, Yorio, Patrick L, Perl, Trish M, Fisher, Edward M

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Crystal structure of the M₅ muscarinic acetylcholine receptor von Vuckovic, Ziva, Gentry, Patrick R., Berizzi, Alice E., Hirata, Kunio, Varghese, Swapna, Thompson, Geoff, van der Westhuizen, Emma T., Burger, Wessel A. C., Rahmani, Raphaël, Valant, Celine, Langmead, Christopher J., Lindsley, Craig W., Baell, Jonathan B., Tobin, Andrew B., Sexton, Patrick M., Christopoulos, Arthur, Thal, David M.

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Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons von Joffe, Max E., Maksymetz, James, Luschinger, Joseph R., Dogra, Shalini, Ferranti, Anthony S., Luessen, Deborah J., Gallinger, Isabel M., Xiang, Zixiu, Branthwaite, Hannah, Melugin, Patrick R., Williford, Kellie M., Centanni, Samuel W., Shields, Brenda C., Lindsley, Craig W., Calipari, Erin S., Siciliano, Cody A., Niswender, Colleen M., Tadross, Michael R., Winder, Danny G., Conn, P. Jeffrey

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Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells von Nagpal, Neha, Wang, Jianing, Zeng, Jing, Lo, Emily, Moon, Diane H., Luk, Kevin, Braun, Roman O., Burroughs, Lauri M., Keel, Sioban B., Reilly, Christopher, Lindsley, R. Coleman, Wolfe, Scot A., Tai, Albert K., Cahan, Patrick, Bauer, Daniel E., Fong, Yick W., Agarwal, Suneet

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Muscarinic M5 receptors modulate ethanol seeking in rats von Berizzi, Alice E., Perry, Christina J., Shackleford, David M., Lindsley, Craig W., Jones, Carrie K., Chen, Nicola A., Sexton, Patrick M., Christopoulos, Arthur, Langmead, Christopher J., Lawrence, Andrew J.

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M1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease von Dwomoh, Louis, Rossi, Mario, Scarpa, Miriam, Khajehali, Elham, Molloy, Colin, Herzyk, Pawel, Mistry, Shailesh N, Bottrill, Andrew R, Sexton, Patrick M, Christopoulos, Arthur, Conn, Jeffrey, Lindsley, Craig W, Bradley, Sophie J, Tobin, Andrew B

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Probing the binding site of novel selective positive allosteric modulators at the M 1 muscarinic acetylcholine receptor von Khajehali, Elham, Valant, Celine, Jörg, Manuela, Tobin, Andrew B, Conn, P Jeffrey, Lindsley, Craig W, Sexton, Patrick M, Scammells, Peter J, Christopoulos, Arthur

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M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location von Foster, Daniel J, Gentry, Patrick R, Lizardi-Ortiz, Jose E, Bridges, Thomas M, Wood, Michael R, Niswender, Colleen M, Sulzer, David, Lindsley, Craig W, Xiang, Zixiu, Conn, P Jeffrey

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Discovery of the First Highly M5-Preferring Muscarinic Acetylcholine Receptor Ligand, an M5 Positive Allosteric Modulator Derived from a Series of 5-Trifluoromethoxy N-Benzyl Isati... von Bridges, Thomas M, Marlo, Joy E, Niswender, Colleen M, Jones, Carrie K, Jadhav, Satyawan B, Gentry, Patrick R, Plumley, Hyekyung C, Weaver, C. David, Conn, P. Jeffrey, Lindsley, Craig W

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M 1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease von Dwomoh, Louis, Rossi, Mario, Scarpa, Miriam, Khajehali, Elham, Molloy, Colin, Herzyk, Pawel, Mistry, Shailesh N, Bottrill, Andrew R, Sexton, Patrick M, Christopoulos, Arthur, Conn, Jeffrey, Lindsley, Craig W, Bradley, Sophie J, Tobin, Andrew B

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Crystal structure of the M 5 muscarinic acetylcholine receptor von Vuckovic, Ziva, Gentry, Patrick R, Berizzi, Alice E, Hirata, Kunio, Varghese, Swapna, Thompson, Geoff, van der Westhuizen, Emma T, Burger, Wessel A C, Rahmani, Raphaël, Valant, Celine, Langmead, Christopher J, Lindsley, Craig W, Baell, Jonathan B, Tobin, Andrew B, Sexton, Patrick M, Christopoulos, Arthur, Thal, David M

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Identification of a Novel Allosteric Site at the M5 Muscarinic Acetylcholine Receptor von Burger, Wessel A. C, Gentry, Patrick R, Berizzi, Alice E, Vuckovic, Ziva, van der Westhuizen, Emma T, Thompson, Geoff, Yeasmin, Mahmuda, Lindsley, Craig W, Sexton, Patrick M, Langmead, Christopher J, Tobin, Andrew B, Christopoulos, Arthur, Valant, Celine, Thal, David M

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Discovery of (S)‑2-Cyclopentyl‑N‑((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro‑1H‑pyrrido[3,4‑b]indole-4-carboxamide (VU0453379): A Novel, CNS Penetrant Glucagon-Like Pep... von Morris, Lindsey C, Nance, Kellie D, Gentry, Patrick R, Days, Emily L, Weaver, C. David, Niswender, Colleen M, Thompson, Analisa D, Jones, Carrie K, Locuson, Chuck W, Morrison, Ryan D, Daniels, J. Scott, Niswender, Kevin D, Lindsley, Craig W

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Probing the binding site of novel selective positive allosteric modulators at the M1 muscarinic acetylcholine receptor von Khajehali, Elham, Valant, Celine, Jörg, Manuela, Tobin, Andrew B., Conn, P. Jeffrey, Lindsley, Craig W., Sexton, Patrick M., Scammells, Peter J., Christopoulos, Arthur

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Identification of a Novel Allosteric Site at the M 5 Muscarinic Acetylcholine Receptor von Burger, Wessel A C, Gentry, Patrick R, Berizzi, Alice E, Vuckovic, Ziva, van der Westhuizen, Emma T, Thompson, Geoff, Yeasmin, Mahmuda, Lindsley, Craig W, Sexton, Patrick M, Langmead, Christopher J, Tobin, Andrew B, Christopoulos, Arthur, Valant, Celine, Thal, David M

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Discovery, Synthesis and Characterization of a Highly Muscarinic Acetylcholine Receptor (mAChR)-Selective M5-Orthosteric Antagonist, VU0488130 (ML381): A Novel Molecular Probe von Gentry, Patrick R., Kokubo, Masaya, Bridges, Thomas M., Cho, Hyekyung P., Smith, Emery, Chase, Peter, Hodder, Peter S., Utley, Thomas J., Rajapakse, Anuruddha, Byers, Frank, Niswender, Colleen M., Morrison, Ryan D., Daniels, J. Scott, Wood, Michael R., Conn, P. Jeffrey, Lindsley, Craig W.

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Restoring Agonist Function at a Chemogenetically Modified M1 Muscarinic Acetylcholine Receptor von Khajehali, Elham, Bradley, Sophie, van der Westhuizen, Emma T, Molloy, Colin, Valant, Celine, Finlayson, Lisa, Lindsley, Craig W, Sexton, Patrick M, Tobin, Andrew B, Christopoulos, Arthur

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Restoring Agonist Function at a Chemogenetically Modified M 1 Muscarinic Acetylcholine Receptor von Khajehali, Elham, Bradley, Sophie, van der Westhuizen, Emma T, Molloy, Colin, Valant, Celine, Finlayson, Lisa, Lindsley, Craig W, Sexton, Patrick M, Tobin, Andrew B, Christopoulos, Arthur

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Discovery and Optimization of Potent and CNS Penetrant M 5 -Preferring Positive Allosteric Modulators Derived from a Novel, Chiral N-(Indanyl)piperidine Amide Scaffold von Bender, Aaron M, Cho, Hyekyung P, Nance, Kellie D, Lingenfelter, Kaelyn S, Luscombe, Vincent B, Gentry, Patrick R, Voigtritter, Karl, Berizzi, Alice E, Sexton, Patrick M, Langmead, Christopher J, Christopoulos, Arthur, Locuson, Charles W, Bridges, Thomas M, Chang, Sichen, O'Neill, Jordan C, Zhan, Xiaoyan, Niswender, Colleen M, Jones, Carrie K, Conn, P Jeffrey, Lindsley, Craig W

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