Exosomes in triple negative breast cancer: Garbage disposals or Trojan horses? von Goh, Chia Yin, Wyse, Cathy, Ho, Matthew, O'Beirne, Ellen, Howard, Jane, Lindsay, Sinéad, Kelly, Pamela, Higgins, Michaela, McCann, Amanda

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Resident bacteria in breast cancer tissue: pathogenic agents or harmless commensals? von O'Connor, Hugh, MacSharry, John, Bueso, Yensi Flores, Lindsay, Sinéad, Kavanagh, Emma L, Tangney, Mark, Clyne, Marguerite, Saldova, Radka, McCann, Amanda

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Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling von Ho, Matthew, Chen, Tianzeng, Liu, Jiye, Dowling, Paul, Hideshima, Teru, Zhang, Li, Morelli, Eugenio, Camci-Unal, Gulden, Wu, Xinchen, Tai, Yu-Tzu, Wen, Kenneth, Samur, Mehmet, Schlossman, Robert L., Mazitschek, Ralph, Kavanagh, Emma L., Lindsay, Sinéad, Harada, Takeshi, McCann, Amanda, Anderson, Kenneth C., O’Gorman, Peter, Bianchi, Giada

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Identification of a novel mutation at the primary dimer interface of GyrA conferring fluoroquinolone resistance in Clostridium difficile von Mac Aogáin, Micheál, Kilkenny, Shauna, Walsh, Claire, Lindsay, Sinéad, Moloney, Geraldine, Morris, Trefor, Jones, Sophie, Rogers, Thomas R.

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Targeting Proteotoxic Stress in Cancer: A Review of the Role that Protein Quality Control Pathways Play in Oncogenesis von Guang, Matthew Ho Zhi, Kavanagh, Emma L, Dunne, Luke Paul, Dowling, Paul, Zhang, Li, Lindsay, Sinéad, Bazou, Despina, Goh, Chia Yin, Hanley, Cathal, Bianchi, Giada, Anderson, Kenneth C, O'Gorman, Peter, McCann, Amanda

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N-Linked glycosylation profiles of therapeutic induced senescent (TIS) triple negative breast cancer cells (TNBC) and their extracellular vesicle (EV) progeny von Kavanagh, Emma L., Halasz, Melinda, Dowling, Paul, Withers, Jo, Lindsay, Sinead, Higgins, Michaela J., Irwin, Jane A., Rudd, Pauline M., Saldova, Radka, McCann, Amanda

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Overexpression of the microRNA miR‐433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells von Weiner‐Gorzel, Karolina, Dempsey, Eugene, Milewska, Malgorzata, McGoldrick, Aloysius, Toh, Valerie, Walsh, Aoibheann, Lindsay, Sinead, Gubbins, Luke, Cannon, Aoife, Sharpe, Daniel, O'Sullivan, Jacintha, Murphy, Madeline, Madden, Stephen F., Kell, Malcolm, McCann, Amanda, Furlong, Fiona

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Abstract 1060: Longitudinal profiling of plasma derived extracellular vesicles (EVs) from women presenting with metastatic triple-negative breast cancer (mTNBC) informs on metastat... von Lindsay, Sinéad, McIntyre, Jennifer, Gubbins, Luke, Smith, Martina, Kerr, Laura, Kavanagh, Emma, Higgins, Michaela J., Hennelly, Bryan, Dowling, Paul, Byrne, Hugh, McCann, Amanda

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Abstract 457: Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic-induced senescent triple-negative breast cancer cells von Kavanagh, Emma L., Lindsay, Sinéad, Halasz, Melinda, Gubbins, Luke C., Weiner-Gorzel, Karolina, Guang, Matthew Ho Zhi, McGoldrick, Aloysius, Collins, Eoin, Henry, Michael, O'Gorman, Peter, Fitzpatrick, Patricia, Higgins, Michaela J., Dowling, Paul, McCann, Amanda

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Linked glycosylation profiles of therapeutic induced senescent (TIS) triple negative breast cancer cells (TNBC) and their extracellular vesicle (EV) progeny von Kavanagh, Emma L, Halasz, Melinda, Dowling, Paul, Withers, Jo, Lindsay, Sinéad, Higgins, Michaela J, Irwin, Jane A, Rudd, Pauline M, Saldova, Radka, McCann, Amanda

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Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial von Seymour, Matthew T, Prof, Thompson, Lindsay C, MSc, Wasan, Harpreet S, Prof, Middleton, Gary, MD, Brewster, Alison E, MD, Shepherd, Stephen F, MD, O'Mahony, M Sinead, MBBS, Maughan, Timothy S, Prof, Parmar, Mahesh, Prof, Langley, Ruth E, PhD

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Impact of probiotics in women with gestational diabetes mellitus on metabolic health: a randomized controlled trial von Lindsay, Karen L., PhD, Brennan, Lorraine, PhD, Kennelly, Maria A., MRCPI, Maguire, Orla C., MSc, Smith, Thomas, PhD, Curran, Sinead, BSc, Coffey, Mary, MSc, Foley, Michael E., MD, Hatunic, Mensud, MD, Shanahan, Fergus, MD, McAuliffe, Fionnuala M., MD

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Genetic analyses of diverse populations improves discovery for complex traits von Wojcik, Genevieve L., Graff, Mariaelisa, Nishimura, Katherine K., Tao, Ran, Haessler, Jeffrey, Gignoux, Christopher R., Highland, Heather M., Patel, Yesha M., Sorokin, Elena P., Avery, Christy L., Belbin, Gillian M., Bien, Stephanie A., Cheng, Iona, Cullina, Sinead, Hodonsky, Chani J., Hu, Yao, Huckins, Laura M., Jeff, Janina, Justice, Anne E., Kocarnik, Jonathan M., Lim, Unhee, Lin, Bridget M., Lu, Yingchang, Nelson, Sarah C., Park, Sung-Shim L., Poisner, Hannah, Preuss, Michael H., Richard, Melissa A., Schurmann, Claudia, Setiawan, Veronica W., Sockell, Alexandra, Vahi, Karan, Verbanck, Marie, Vishnu, Abhishek, Walker, Ryan W., Young, Kristin L., Zubair, Niha, Acuña-Alonso, Victor, Ambite, Jose Luis, Barnes, Kathleen C., Boerwinkle, Eric, Bottinger, Erwin P., Bustamante, Carlos D., Caberto, Christian, Canizales-Quinteros, Samuel, Conomos, Matthew P., Deelman, Ewa, Do, Ron, Doheny, Kimberly, Fernández-Rhodes, Lindsay, Fornage, Myriam, Hailu, Benyam, Heiss, Gerardo, Henn, Brenna M., Hindorff, Lucia A., Jackson, Rebecca D., Laurie, Cecelia A., Laurie, Cathy C., Li, Yuqing, Lin, Dan-Yu, Moreno-Estrada, Andres, Nadkarni, Girish, Norman, Paul J., Pooler, Loreall C., Reiner, Alexander P., Romm, Jane, Sabatti, Chiara, Sandoval, Karla, Sheng, Xin, Stahl, Eli A., Stram, Daniel O., Thornton, Timothy A., Wassel, Christina L., Wilkens, Lynne R., Winkler, Cheryl A., Yoneyama, Sachi, Buyske, Steven, Haiman, Christopher A., Kooperberg, Charles, Le Marchand, Loic, Loos, Ruth J. F., Matise, Tara C., North, Kari E., Peters, Ulrike, Kenny, Eimear E., Carlson, Christopher S.

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Deresuscitation of Patients With Iatrogenic Fluid Overload Is Associated With Reduced Mortality in Critical Illness von Silversides, Jonathan A., Fitzgerald, Emma, Manickavasagam, Uma S., Lapinsky, Stephen E., Nisenbaum, Rosane, Hemmings, Noel, Nutt, Christopher, Trinder, T. John, Pogson, David G., Fan, Eddy, Ferguson, Andrew J., McAuley, Daniel F., Marshall, John C.

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Protecting older people living in care homes from COVID-19: a protocol for a mixed-methods study to understand the challenges and solutions to implementing social distancing and is... von Fitzpatrick, Joanne M, Rafferty, Anne Marie, Hussein, Shereen, Ezhova, Ivanka, Palmer, Sinead, Adams, Richard, Rees, Lindsay, Brearley, Sally, Sims, Sarah, Harris, Ruth

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Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors von Root, Adam R., Guntas, Gurkan, Katragadda, Madan, Apgar, James R., Narula, Jatin, Chang, Chew Shun, Hanscom, Sara, McKenna, Matthew, Wade, Jason, Meade, Caryl, Ma, Weijun, Guo, Yongjing, Liu, Yan, Duan, Weili, Hendershot, Claire, King, Amy C., Zhang, Yan, Sousa, Eric, Tam, Amy, Benard, Susan, Yang, Han, Kelleher, Kerry, Jin, Fang, Piche-Nicholas, Nicole, Keating, Sinead E., Narciandi, Fernando, Lawrence-Henderson, Rosemary, Arai, Maya, Stochaj, Wayne R., Svenson, Kristine, Mosyak, Lidia, Lam, Khetemcnee, Francis, Christopher, Marquette, Kimberly, Wroblewska, Liliana, Zhu, H. Lily, Sheehan, Alfredo Darmanin, LaVallie, Edward R., D'Antona, Aaron M., Betts, Alison, King, Lindsay, Rosfjord, Edward, Cunningham, Orla, Lin, Laura, Sapra, Puja, Tchistiakova, Lioudmila, Mathur, Divya, Bloom, Laird

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Social Distancing and Isolation Strategies to Prevent and Control the Transmission of COVID-19 and Other Infectious Diseases in Care Homes for Older People: An International Review von Sims, Sarah, Harris, Ruth, Hussein, Shereen, Rafferty, Anne Marie, Desai, Amit, Palmer, Sinead, Brearley, Sally, Adams, Richard, Rees, Lindsay, Fitzpatrick, Joanne M

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Measuring the population burden of injuries--implications for global and national estimates: a multi-centre prospective UK longitudinal study von Lyons, Ronan A, Kendrick, Denise, Towner, Elizabeth M, Christie, Nicola, Macey, Steven, Coupland, Carol, Gabbe, Belinda J

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Comparison of the two most commonly used treatments for pyoderma gangrenosum: results of the STOP GAP randomised controlled trial von Ormerod, Anthony D, Thomas, Kim S, Craig, Fiona E, Mitchell, Eleanor, Greenlaw, Nicola, Norrie, John, Mason, James M, Walton, Shernaz, Johnston, Graham A, Williams, Hywel C

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A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson disease von RICHARD, I. H, MCDERMOTT, M. P, MANNING, C, MARSH, L, SHULMAN, L, FERNANDEZ, H. H, BLACK, K. J, PANISSET, M, CHRISTINE, C. W, JIANG, W, SINGER, C, HORN, S, KURLAN, R, PFEIFFER, R, ROTTENBERG, D, SLEVIN, J, ELMER, L, PRESS, D, HYSON, H. C, MCDONALD, W, LYNESS, J. M, COMO, P. G, PEARSON, N, FACTOR, S. A, JUNCOS, J, SERRANO RAMOS, C, BRODSKY, M

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