High-content assays for evaluating cellular and hepatic diacylglycerol acyltransferase activity von Qi, Jenson, Lang, Wensheng, Giardino, Edward, Caldwell, Gary W., Smith, Charles, Minor, Lisa K., Darrow, Andrew L., Willemsens, Gustaaf, DeWaepenaert, Katharina, Roevens, Peter, Linders, Joannes T.M., Liang, Yin, Connelly, Margery A.

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Blockade of the IKs potassium channel: An overlooked cardiovascular liability in drug safety screening? von Towart, Rob, Linders, Joannes T.M., Hermans, An N., Rohrbacher, Jutta, van der Linde, Henk J., Ercken, Martine, Cik, Miroslav, Roevens, Peter, Teisman, Ard, Gallacher, David J.

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Design, synthesis and characterisation of a novel type II B-RAF paradox breaker inhibitor von Arora, Rohit, Linders, Joannes T.M., Aci-Sèche, Samia, Verheyen, Thomas, Van Heerde, Erika, Brehmer, Dirk, Chaikuad, Apirat, Knapp, Stefan, Bonnet, Pascal

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Structural Investigation of B‑Raf Paradox Breaker and Inducer Inhibitors von Arora, Rohit, Di Michele, Michela, Stes, Elisabeth, Vandermarliere, Elien, Martens, Lennart, Gevaert, Kris, Van Heerde, Erika, Linders, Joannes T. M, Brehmer, Dirk, Jacoby, Edgar, Bonnet, Pascal

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MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells von Beke, Lijs, Kig, Cenk, Linders, Joannes T M, Boens, Shannah, Boeckx, An, van Heerde, Erika, Parade, Marc, De Bondt, An, Van den Wyngaert, Ilse, Bashir, Tarig, Ogata, Souichi, Meerpoel, Lieven, Van Eynde, Aleyde, Johnson, Christopher N, Beullens, Monique, Brehmer, Dirk, Bollen, Mathieu

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Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling von Wandinger, Sebastian K, Lahortiga, Idoya, Jacobs, Kris, Klammer, Martin, Jordan, Nicole, Elschenbroich, Sarah, Parade, Marc, Jacoby, Edgar, Linders, Joannes T M, Brehmer, Dirk, Cools, Jan, Daub, Henrik

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KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting von Wrobel, Eva, Rothenberg, Ina, Krisp, Christoph, Hundt, Franziska, Fraenzel, Benjamin, Eckey, Karina, Linders, Joannes T. M., Gallacher, David J., Towart, Rob, Pott, Lutz, Pusch, Michael, Yang, Tao, Roden, Dan M., Kurata, Harley T., Schulze-Bahr, Eric, Strutz-Seebohm, Nathalie, Wolters, Dirk, Seebohm, Guiscard

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Probes for narcotic receptor mediated phenomena. Part 31: Synthesis of rac-(3R,6aS,11aS)-2-methyl-1,3,4,5,6,11a-hexahydro-2H-3,6a-methanobenzofuro[2,3-c]azocine-10-ol, and azocine-... von Tadic, Dragana, Linders, Joannes T.M, Flippen-Anderson, Judith L, Jacobson, Arthur E, Rice, Kenner C

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Limited Proteolysis Combined with Stable Isotope Labeling Reveals Conformational Changes in Protein (Pseudo)kinases upon Binding Small Molecules von Di Michele, Michela, Stes, Elisabeth, Vandermarliere, Elien, Arora, Rohit, Astorga-Wells, Juan, Vandenbussche, Jonathan, van Heerde, Erika, Zubarev, Roman, Bonnet, Pascal, Linders, Joannes T. M, Jacoby, Edgar, Brehmer, Dirk, Martens, Lennart, Gevaert, Kris

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Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling von Wandinger, Sebastian K, Lahortiga, Idoya, Jacobs, Kris, Klammer, Martin, Jordan, Nicole, Elschenbroich, Sarah, Parade, Marc, Jacoby, Edgar, Linders, Joannes T.M, Brehmer, Dirk, Cools, Jan, Daub, Henrik

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Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase von Johnson, Christopher N, Berdini, Valerio, Beke, Lijs, Bonnet, Pascal, Brehmer, Dirk, Coyle, Joseph E, Day, Phillip J, Frederickson, Martyn, Freyne, Eddy J. E, Gilissen, Ron A. H. J, Hamlett, Christopher C. F, Howard, Steven, Meerpoel, Lieven, McMenamin, Rachel, Patel, Sahil, Rees, David C, Sharff, Andrew, Sommen, François, Wu, Tongfei, Linders, Joannes T. M

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Structure-Based Design of Type II Inhibitors Applied to Maternal Embryonic Leucine Zipper Kinase von Johnson, Christopher N, Adelinet, Christophe, Berdini, Valerio, Beke, Lijs, Bonnet, Pascal, Brehmer, Dirk, Calo, Frederick, Coyle, Joseph E, Day, Phillip J, Frederickson, Martyn, Freyne, Eddy J. E, Gilissen, Ron A. H. J, Hamlett, Christopher C. F, Howard, Steven, Meerpoel, Lieven, Mevellec, Laurence, McMenamin, Rachel, Pasquier, Elisabeth, Patel, Sahil, Rees, David C, Linders, Joannes T. M

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Abstract 2936: JNJ-47117096, a selective small molecule inhibitor of the MELK oncogene decreases DNA damage tolerance in highly proliferating cancer cells von Beke, Lijs, Linders, Joannes T.m., Kig, Cenk, Boeckx, An, Heerde, Erika van, Wuyts, Dirk, Parade, Marc, Meerpoel, Lieven, Johnson, Chris, Beullens, Monique, Bollen, Mathieu, Brehmer, Dirk

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An expedient synthesis of 9-keto-2-methyl-5-(dimethoxyphenyl)morphans von Linders, Joannes T.M, Flippen-Anderson, Judith L, George, Clifford F, Rice, Kenner C

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MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells von Beke, Lijs, Kig, Cenk, Linders, Joannes T.M, Boens, Shannah, Boeckx, An, van Heerde, Erika, Parade, Marc, De Bondt, An, Van den Wyngaert, Ilse, Bashir, Tarig, Ogata, Souichi, Meerpoel, Lieven, Van Eynde, Aleyde, Johnson, Christopher N, Beullens, Monique, Brehmer, Dirk, Bollen, Mathieu

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Synthesis and Biological Evaluation of Methylene-Bridged Analogs of the Potent Cannabinoid Receptor Antagonist Rimonabant von Ślusarczyk, Magdalena, De Borggraeve, Wim M., Hoornaert, Georges, Deroose, Frederik, Linders, Joannes T. M.

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An expeditious preparation of E-2-amino-5-hydroxyadamantane and its Z-isomer von Jaroskova, Libuse, Van der Veken, Louis, de Belser, Paul, Diels, Gaston, de Groot, Alex, Linders, Joannes T.M.

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Probes for Narcotic Receptor-Mediated Phenomena. 33. Construction of a Strained trans-5,6-Ring System by Displacement of a Nitro-Activated Aromatic Fluorine. Synthesis of the Penul... von Hashimoto, Akihiro, Przybyl, Anna K, Linders, Joannes T. M, Kodato, Shinichi, Tian, Xinrong, Deschamps, Jeffrey R, George, Clifford, Flippen-Anderson, Judith L, Jacobson, Arthur E, Rice, Kenner C

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Blockade of the I Ks potassium channel: An overlooked cardiovascular liability in drug safety screening? von Towart, Rob, Linders, Joannes T.M., Hermans, An N., Rohrbacher, Jutta, van der Linde, Henk J., Ercken, Martine, Cik, Miroslav, Roevens, Peter, Teisman, Ard, Gallacher, David J.

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Synthesis and Biological Evaluation of Bridged Analogues of the Platelet Aggregation Inhibitor Trifenagrel von Slusarczyk, Magdalena, De Borggraeve, Wim, Hoornaert, Georges, Robeyns, Koen, Van Meervelt, Luc, Wu, Tongfei, Deroose, Frederik, Linders, Joannes T.M

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