Receptor/ligand sorting along the endocytic pathway von Linderman, Jennifer J, Lauffenburger, Douglas A

Volltext

THE EFFECTS OF GROWTH HORMONE (GH) AND FUNCTIONAL OVERLOAD ON SOLEUS MASS AND OXIDATIVE CAPACITY IN HYPOPHYSECTOMIZED RATS 368 von Jacobs, K. A., Grindeland, R. E., Bigbee, A. J, Lauderdale, M. A., Finch, B. C., Azevedo, J. A., Linderman, J. A

Volltext

Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans von Lee, Paul, Linderman, Joyce D., Smith, Sheila, Brychta, Robert J., Wang, Juan, Idelson, Christopher, Perron, Rachel M., Werner, Charlotte D., Phan, Giao Q., Kammula, Udai S., Kebebew, Electron, Pacak, Karel, Chen, Kong Y., Celi, Francesco S.

Volltext

Antibodies with 'Original Antigenic Sin' Properties Are Valuable Components of Secondary Immune Responses to Influenza Viruses von Linderman, Susanne L, Hensley, Scott E

Volltext

Dynamic balance of pro‐ and anti‐inflammatory signals controls disease and limits pathology von Cicchese, Joseph M., Evans, Stephanie, Hult, Caitlin, Joslyn, Louis R., Wessler, Timothy, Millar, Jess A., Marino, Simeone, Cilfone, Nicholas A., Mattila, Joshua T., Linderman, Jennifer J., Kirschner, Denise E.

Volltext

Lipid raft-mediated regulation of G-protein coupled receptor signaling by ligands which influence receptor dimerization: a computational study von Fallahi-Sichani, Mohammad, Linderman, Jennifer J

Volltext

Mechanisms of Resistance to Crizotinib in Patients with ALK Gene Rearranged Non―Small Cell Lung Cancer von DOEBELE, Robert C, PILLING, Amanda B, VARELLA-GARCIA, Marileila, ROSS CAMIDGE, D, AISNER, Dara L, KUTATELADZE, Tatiana G, LE, Anh T, WEICKHARDT, Andrew J, KONDO, Kimi L, LINDERMAN, Derek J, HEASLEY, Lynn E, FRANKLIN, Wilbur A

Volltext

Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity von O'Mara, Alana E, Johnson, James W, Linderman, Joyce D, Brychta, Robert J, McGehee, Suzanne, Fletcher, Laura A, Fink, Yael A, Kapuria, Devika, Cassimatis, Thomas M, Kelsey, Nathan, Cero, Cheryl, Sater, Zahraa Abdul, Piccinini, Francesca, Baskin, Alison S, Leitner, Brooks P, Cai, Hongyi, Millo, Corina M, Dieckmann, William, Walter, Mary, Javitt, Norman B, Rotman, Yaron, Walter, Peter J, Ader, Marilyn, Bergman, Richard N, Herscovitch, Peter, Chen, Kong Y, Cypess, Aaron M

Volltext

Influenza vaccine-induced human bone marrow plasma cells decline within a year after vaccination von Davis, Carl W, Jackson, Katherine J L, McCausland, Megan M, Darce, Jaime, Chang, Cathy, Linderman, Susanne L, Chennareddy, Chakravarthy, Gerkin, Rebecca, Brown, Shantoria J, Wrammert, Jens, Mehta, Aneesh K, Cheung, Wan Cheung, Boyd, Scott D, Waller, Edmund K, Ahmed, Rafi

Volltext

Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity von Chen, Kong Y., Brychta, Robert J., Abdul Sater, Zahraa, Cassimatis, Thomas M., Cero, Cheryl, Fletcher, Laura A., Israni, Nikita S., Johnson, James W., Lea, Hannah J., Linderman, Joyce D., O'Mara, Alana E., Zhu, Kenneth Y., Cypess, Aaron M.

Volltext

An approximate line attractor in the hypothalamus encodes an aggressive state von Nair, Aditya, Karigo, Tomomi, Yang, Bin, Ganguli, Surya, Schnitzer, Mark J., Linderman, Scott W., Anderson, David J., Kennedy, Ann

Volltext

Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach von Pienaar, Elsje, Sarathy, Jansy, Prideaux, Brendan, Dietzold, Jillian, Dartois, Véronique, Kirschner, Denise E, Linderman, Jennifer J

Volltext

Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space von Makowski, Emily K., Kinnunen, Patrick C., Huang, Jie, Wu, Lina, Smith, Matthew D., Wang, Tiexin, Desai, Alec A., Streu, Craig N., Zhang, Yulei, Zupancic, Jennifer M., Schardt, John S., Linderman, Jennifer J., Tessier, Peter M.

Volltext

Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection von Cilfone, Nicholas A, Perry, Cory R, Kirschner, Denise E, Linderman, Jennifer J

Volltext

Engineering RGD nanopatterned hydrogels to control preosteoblast behavior: A combined computational and experimental approach von Comisar, Wendy A, Kazmers, Nikolas H, Mooney, David J, Linderman, Jennifer J

Volltext

An Agent-Based Systems Pharmacology Model of the Antibody-Drug Conjugate Kadcyla to Predict Efficacy of Different Dosing Regimens von Menezes, Bruna, Cilliers, Cornelius, Wessler, Timothy, Thurber, Greg M., Linderman, Jennifer J.

Volltext

Emergence and selection of isoniazid and rifampin resistance in tuberculosis granulomas von Pienaar, Elsje, Linderman, Jennifer J, Kirschner, Denise E

Volltext

The CXCL12/CXCR7 signaling axis, isoforms, circadian rhythms, and tumor cellular composition dictate gradients in tissue von Spinosa, Phillip C, Luker, Kathryn E, Luker, Gary D, Linderman, Jennifer J

Volltext

Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection von Marino, Simeone, Cilfone, Nicholas A, Mattila, Joshua T, Linderman, Jennifer J, Flynn, JoAnne L, Kirschner, Denise E

Volltext

Key green chemistry research areas—a perspective from pharmaceutical manufacturers von Constable, David J. C., Dunn, Peter J., Hayler, John D., Humphrey, Guy R., Leazer, Jr, Johnnie L., Linderman, Russell J., Lorenz, Kurt, Manley, Julie, Pearlman, Bruce A., Wells, Andrew, Zaks, Aleksey, Zhang, Tony Y.

Volltext