878 T cell immunotherapies recruit and activate neutrophils to eliminate tumor antigen escape variants von Hirschhorn, Daniel, Budhu, Sadna, Kraehenbuehl, Lukas, Gigoux, Mathieu, Schröder, David, Chow, Andrew, Ricca, Jacob M, Gasmi, Billel, De Henau, Olivier, Mangarin, Levi Mark B, Li, Yanyun, Flamar, Anne-Laure, Choi, Heyjin, Cortez, Czrina A, Liu, Cailian, Holland, Aliya, Schad, Sara, Schulze, Isabell, Hamadene, Linda, Warner, Allison Betof, Hollmann, Travis, Arora, Arshi, Panageas, Katherine S, Duhen, Rebekka, Weinberg, Andrew D, Rizzuto, Gabrielle A, Spencer, Christine N, Ng, David, He, Xue-Yan, Albrengues, Jean, Redmond, David, Egeblad, Mikala, Wolchok, Jedd D, Merghoub, Taha

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Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness von Hirschhorn, Daniel, Betof Warner, Allison, Maniyar, Rachana, Chow, Andrew, Mangarin, Levi Mb, Cohen, Adam D, Hamadene, Linda, Rizzuto, Gabrielle A, Budhu, Sadna, Suek, Nathan, Liu, Cailian, Houghton, Alan N, Merghoub, Taha, Wolchok, Jedd D

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T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants von Hirschhorn, Daniel, Budhu, Sadna, Kraehenbuehl, Lukas, Gigoux, Mathieu, Schröder, David, Chow, Andrew, Ricca, Jacob M., Gasmi, Billel, De Henau, Olivier, Mangarin, Levi Mark B., Li, Yanyun, Hamadene, Linda, Flamar, Anne-Laure, Choi, Hyejin, Cortez, Czrina A., Liu, Cailian, Holland, Aliya, Schad, Sara, Schulze, Isabell, Betof Warner, Allison, Hollmann, Travis J., Arora, Arshi, Panageas, Katherine S., Rizzuto, Gabrielle A., Duhen, Rebekka, Weinberg, Andrew D., Spencer, Christine N., Ng, David, He, Xue-Yan, Albrengues, Jean, Redmond, David, Egeblad, Mikala, Wolchok, Jedd D., Merghoub, Taha

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Abstract 1795: Combination of cyclophosphamide chemotherapy with immune modulation overcomes resistance to checkpoint blockade in a pre-clinical melanoma model von Warner, Allison Betof, Hirschhorn, Daniel, Mangarin, Levi M., Hamadene, Linda, Cohen, Adam D., Rizzuto, Gabrielle A., Wolchok, Jedd D., Merghoub, Taha

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789 Immune checkpoint blockade augments cyclophosphamide induced anti-tumor immunity by expanding effector CD8+ T cell clones in a preclinical melanoma model von George, Mariam M, Hamadene, Linda, Ceglia, Nicholas J, Marouf, Yacine, Hirschhorn, Daniel, Houghton, Alan N, Wolchok, Jedd D, Warner, Allison B, Merghoub, Taha

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Abstract 4167: Combination of cyclophosphamide with immune checkpoint blockade inhibition elicits potent tumor control in a preclinical melanoma model von George, Mariam M., Warner, Allison Betof, Hamadene, Linda, Hirschhorn, Daniel, Houghton, Alan N., Wolchok, Jedd D., Merghoub, Taha

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1148 Signal-regulatory protein alpha (SIRPα) confers tumor cell resistance to anti-tumor immunity von Chien-Huan Weng, Hamadene, Linda, Eghbali, Shabnam, Venkatesh, Divya, Monette, Sébastien, Levi Mangarin, Samaan, Fadi, Liu, Cailian, Holland, Pamela, Wolchok, Jedd, Taha Merghoub

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Abstract 6150: Potential role of CD47 in T cell exhaustion program von Weng, Chien-Huan, Samaan, Fadi, Budhu, Sadna, Mangarin, Levi, Monette, Sébastien, Liu, Cailian, Pourpe, Stephane, Hamadene, Linda, Zhong, Hong, Yang, Xia, Schroder, David, Zappasodi, Roberta, Holland, Pamela, Wolchok, Jedd D., Merghoub, Taha

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789 Immune checkpoint blockade augments cyclophosphamide induced anti-tumor immunity by expanding effector CD8+ T cell clones in a preclinical melanoma model von Alan N Houghton, Jedd D Wolchok, Taha Merghoub, Daniel Hirschhorn, Linda Hamadene, Yacine Marouf, Allison B Warner, Mariam M George, Nicholas J Ceglia

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Begabung verändert – förderliche Lernwelten erforschen, gestalten, implementieren

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