Multiple Criteria Decision Analysis for HTA across four EU Member States: Piloting the Advance Value Framework von Angelis, A., Linch, M., Montibeller, G., Molina-Lopez, T., Zawada, A., Orzel, K., Arickx, F., Espin, J., Kanavos, P.

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Positioning checkpoint blockade in urothelial cancer: PURE-01 and PEANUTS von Linch, M., Lee, Alvin J.X.

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Prostate cancers that ‘Wnt’ respond to abiraterone von Linch, M., Attard, G.

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Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters von Linch, M., Goh, G., Hiley, C., Shanmugabavan, Y., McGranahan, N., Rowan, A., Wong, Y.N.S., King, H., Furness, A., Freeman, A., Linares, J., Akarca, A., Herrero, J., Rosenthal, R., Harder, N., Schmidt, G., Wilson, G.A., Birkbak, N.J., Mitter, R., Dentro, S., Cathcart, P., Arya, M., Johnston, E., Scott, R., Hung, M., Emberton, M., Attard, G., Szallasi, Z., Punwani, S., Quezada, S.A., Marafioti, T., Gerlinger, M., Ahmed, H.U., Swanton, C.

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A phase II study investigating the safety and efficacy of neoadjuvent atezolizumab in muscle invasive bladder cancer (ABACUS) von Castellano, D., Duran, I., Rodríguez-Vida, A., Crabb, S.J., van der Heijden, M.S., Font Pous, A., Gravis, G., Anido Herranz, U., Protheroe, A., Ravaud, A., Maillet, D., Mendez-Vidal, M.J., Suarez, C., Lorch, A., Sternberg, C.N., Linch, M., Sarker, S.-J., Notta, J., Mousa, K., Powles, T.B.

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AZD8186, a potent and selective inhibitor of PI3Kβ/δ, as monotherapy and in combination with abiraterone acetate plus prednisone (AAP), in patients (pts) with metastatic castrate-r... von de Bono, J.S., Hansen, A., Choudhury, A.D., Cook, N., Heath, E.I., Higano, C., Linch, M., Martin-Liberal, J., Rathkopf, D.E., Wisinski, K.B., Barry, S., de Bruin, E., Brugger, W., Colebrook, S., Klinowska, T., Moschetta, M., Mortimer, P.G.S., Siu, L.L., Shapiro, G.

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Targeting protein kinase C in sarcoma von Martin-Liberal, J., Cameron, A.J., Claus, J., Judson, I.R., Parker, P.J., Linch, M.

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Novel therapeutic agents in ovarian cancer von Agarwal, R., Linch, M., Kaye, S.B.

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An Audit of the Use of Cabazitaxel for the Treatment of Metastatic Castrate Resistant Prostate Cancer (mCRPC) Compared with Previous Experience with ECarboF (Epirubicin, Carboplati... von Al-Bakir, M, Williams, S, Davda, R, Mascoll, J, Lynch, C, Mitra, A, Payne, H, Dickson, J, Harland, S, Lopes, A, McGovern, U, Chau, N.-M, Linch, M

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Experience in a UK cancer centre of weekly paclitaxel in the treatment of relapsed ovarian and primary peritoneal cancer von Linch, M, Stavridi, F, Hook, J, Barbachano, Y, Gore, M, Kaye, S.B

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A Retrospective Evaluation of Clinical Outcomes of Patients Undergoing Cystectomy for Bladder Cancer at a Specialist Centre; Real-world Data from University College London Hospital von Veli, M., Freeman, A., Alifrangis, C., Sridhar, A., Linch, M., McGovern, U.

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1622P A phase II study of the first-in-class oral innate immune activator BXCL701 with pembrolizumab in patients with metastatic castration-resistant prostate cancer (mCRPC): Long-... von Aggarwal, R., Tagawa, S.T., Monk, P., Zhu, X., Jones, R.J., Linch, M., Costin, D., de Bono, J.S., Karsh, L.I., Petrylak, D.P., Borderies, P., Deshpande, R., O'Neill, V., Zhang, J.

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1397P Phase I results of exicorilant plus enzalutamide in patients with castration-resistant prostate cancer von Linch, M., Liu, G., Crabb, S.J., Beer, T.M., Heath, E., Gordon, M., de Bono, J.S., Pashova, H.I., Tudor, I.C., Custodio, J.M., Mann, G., Morris, M.J.

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610P BXCL701 - 1st-in-class oral activator of systemic innate immunity-combined with pembrolizumab, in men with metastatic castration-resistant prostate cancer (mCRPC): Phase II re... von Monk, P., Zhang, J., Costin, D., Petrylak, D.P., Tagawa, S.T., Karsh, L.I., Zhu, X., Linch, M., Jones, R., Borderies, P., O'Neill, V., Aggarwal, R.R.

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Renal tubular acidosis due to oxaliplatin von Linch, M, Cunningham, D, Mingo, O, Stiles, A, Farquhar-Smith, WP

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Copy number architectures define treatment-mediated selection of lethal prostate cancer clones von Hasan, AMM, Cremaschi, P, Wetterskog, D, Jayaram, A, Wong, SQ, Williams, S, Pasam, A, Trigos, A, Trujillo, B, Grist, E, Friedrich, S, Vainauskas, O, Parry, M, Ismail, M, Devlies, W, Wingate, A, Linch, M, Naceur-Lombardelli, C, PEACE consortium, Swanton, C, Jamal-Hanjani, M, Lise, S, Sandhu, S, Attard, G

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2363MO A phase II study investigating the safety and efficacy of neoadjuvant atezolizumab in non-urothelial, muscle invasive bladder cancer (ABACUS-2) von Szabados, B.E., Nogueron Martinez, E., Alvarez Marquez, F.J., Castellano Gauna, D.E., Rodriguez-Vida, A., Garcias de Espana, M.C., Hussain, S.A., Alvarez Fernandez, C., Linch, M., Bonfill Abella, T., Gross Goupil, M., Kelly, J., Jones, R.J., Crabb, S., Beltran, L., Garonce-Hediger, R., Rakebrandt, N.J., Georgescu, R., Ackerman, C., Powles, T.B.

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1389P Two-year follow-up of KEYNOTE-365 cohort D: Pembrolizumab (pembro) plus abiraterone acetate (abi) and prednisone in patients with chemotherapy-naive metastatic castration-res... von Linch, M., Ferrario, C., Stoeckle, M., Laguerre, B., Arranz Arija, J.A., Todenhöfer, T., Fong, P.C., Piulats Rodriguez, J.M., Berry, W., Emmenegger, U., Mourey, L., Mar, N., Appleman, L.J., Joshua, A., Conter, H.J., Li, X.T., Schloss, C., Poehlein, C.H., de Bono, J.S., Yu, E.Y.

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199O A phase II study investigating neoadjuvant atezolizumab in cisplatin-ineligible patients with muscle-invasive bladder cancer: Final analysis von Szabados, B.E., Rodriguez-Vida, A., Duran, I., Crabb, S.J., van der Heijden, M.S., Pous, A. Font, Gravis, G., Herranz, U. Anido, Protheroe, A., Ravaud, A., Maillet, D., Mendez, M.J., Suarez, C., Linch, M., Prendergast, A., Tyson, C., Mousa, K., Castellano, D., Powles, T.B.

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P223 Evaluating atezolizumab in patients with urinary tract squamous cell carcinoma (AURORA) – a single arm, open-label, multicentre, phase II clinical trial in progress von Lawrence, M., Crabb, S., Wickens, R., Bibby, S.J., Dunkley, D., Knight, A., Jones, R., Birtle, A., Huddart, R., Linch, M., Martin, J., Coleman, A., Irvine, N., Boukas, K., Markham, H., Griffiths, G.

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