Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement von Kim, Edward S, Bruinooge, Suanna S, Roberts, Samantha, Ison, Gwynn, Lin, Nancy U, Gore, Lia, Uldrick, Thomas S, Lichtman, Stuart M, Roach, Nancy, Beaver, Julia A, Sridhara, Rajeshwari, Hesketh, Paul J, Denicoff, Andrea M, Garrett-Mayer, Elizabeth, Rubin, Eric, Multani, Pratik, Prowell, Tatiana M, Schenkel, Caroline, Kozak, Marina, Allen, Jeff, Sigal, Ellen, Schilsky, Richard L

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iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics von Seymour, Lesley, Prof, Bogaerts, Jan, PhD, Perrone, Andrea, MD, Ford, Robert, MD, Schwartz, Lawrence H, Prof, Mandrekar, Sumithra, Prof, Lin, Nancy U, MD, Litière, Saskia, PhD, Dancey, Janet, Prof, Chen, Alice, MD, Hodi, F Stephen, Prof, Therasse, Patrick, MD, Hoekstra, Otto S, Prof, Shankar, Lalitha K, MD, Wolchok, Jedd D, MD, Ballinger, Marcus, PhD, Caramella, Caroline, MD, de Vries, Elisabeth G E, Prof

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STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer von Wang, Qiwei, Bergholz, Johann S., Ding, Liya, Lin, Ziying, Kabraji, Sheheryar K., Hughes, Melissa E., He, Xiadi, Xie, Shaozhen, Jiang, Tao, Wang, Weihua, Zoeller, Jason J., Kim, Hye-Jung, Roberts, Thomas M., Konstantinopoulos, Panagiotis A., Matulonis, Ursula A., Dillon, Deborah A., Winer, Eric P., Lin, Nancy U., Zhao, Jean J.

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Management of Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases: ASCO Guideline Update von Ramakrishna, Naren, Anders, Carey K, Lin, Nancy U, Morikawa, Aki, Temin, Sarah, Chandarlapaty, Sarat, Crews, Jennie R, Davidson, Nancy E, Franzoi, Maria Alice B, Kirshner, Jeffrey J, Krop, Ian E, Patt, Debra A, Perlmutter, Jane, Giordano, Sharon H

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TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes von Tung, Nadine M, Robson, Mark E, Ventz, Steffen, Santa-Maria, Cesar A, Nanda, Rita, Marcom, Paul K, Shah, Payal D, Ballinger, Tarah J, Yang, Eddy S, Vinayak, Shaveta, Melisko, Michelle, Brufsky, Adam, DeMeo, Michelle, Jenkins, Colby, Domchek, Susan, D'Andrea, Alan, Lin, Nancy U, Hughes, Melissa E, Carey, Lisa A, Wagle, Nick, Wulf, Gerburg M, Krop, Ian E, Wolff, Antonio C, Winer, Eric P, Garber, Judy E

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Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies von Nayar, Utthara, Cohen, Ofir, Kapstad, Christian, Cuoco, Michael S., Waks, Adrienne G., Wander, Seth A., Painter, Corrie, Freeman, Samuel, Persky, Nicole S., Marini, Lori, Helvie, Karla, Oliver, Nelly, Rozenblatt-Rosen, Orit, Ma, Cynthia X., Regev, Aviv, Winer, Eric P., Lin, Nancy U., Wagle, Nikhil

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CNS metastases in breast cancer: old challenge, new frontiers von Lin, Nancy U, Amiri-Kordestani, Laleh, Palmieri, Diane, Liewehr, David J, Steeg, Patricia S

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Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer von Barroso-Sousa, Romualdo, Keenan, Tanya E, Pernas, Sonia, Exman, Pedro, Jain, Esha, Garrido-Castro, Ana C, Hughes, Melissa, Bychkovsky, Brittany, Umeton, Renato, Files, Janet L, Lindeman, Neal I, MacConaill, Laura E, Hodi, F Stephen, Krop, Ian E, Dillon, Deborah, Winer, Eric P, Wagle, Nikhil, Lin, Nancy U, Mittendorf, Elizabeth A, Van Allen, Eliezer M, Tolaney, Sara M

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Brain Metastases: The HER2 Paradigm von Lin, Nancy U, Winer, Eric P

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Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment von Garrido-Castro, Ana C, Lin, Nancy U, Polyak, Kornelia

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Modernizing Clinical Trial Eligibility Criteria: Recommendations of the American Society of Clinical Oncology-Friends of Cancer Research Brain Metastases Working Group von Lin, Nancy U, Prowell, Tatiana, Tan, Antoinette R, Kozak, Marina, Rosen, Oliver, Amiri-Kordestani, Laleh, White, Julia, Sul, Joohee, Perkins, Louise, Beal, Katherine, Gaynor, Richard, Kim, Edward S

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Consensus recommendations for a standardized brain tumor imaging protocol for clinical trials in brain metastases von Kaufmann, Timothy J, Smits, Marion, Boxerman, Jerrold, Huang, Raymond, Barboriak, Daniel P, Weller, Michael, Chung, Caroline, Tsien, Christina, Brown, Paul D, Shankar, Lalitha, Galanis, Evanthia, Gerstner, Elizabeth, van den Bent, Martin J, Burns, Terry C, Parney, Ian F, Dunn, Gavin, Brastianos, Priscilla K, Lin, Nancy U, Wen, Patrick Y, Ellingson, Benjamin M

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Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation von Xing, Yan, Lin, Nancy U, Maurer, Matthew A, Chen, Huiqin, Mahvash, Armeen, Sahin, Aysegul, Akcakanat, Argun, Li, Yisheng, Abramson, Vandana, Litton, Jennifer, Chavez-MacGregor, Mariana, Valero, Vicente, Piha-Paul, Sarina A, Hong, David, Do, Kim-Anh, Tarco, Emily, Riall, Dianna, Eterovic, Agda Karina, Wulf, Gerburg M, Cantley, Lewis C, Mills, Gordon B, Doyle, L Austin, Winer, Eric, Hortobagyi, Gabriel N, Gonzalez-Angulo, Ana Maria, Meric-Bernstam, Funda

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Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets von Brastianos, Priscilla K, Carter, Scott L, Santagata, Sandro, Cahill, Daniel P, Taylor-Weiner, Amaro, Jones, Robert T, Van Allen, Eliezer M, Lawrence, Michael S, Horowitz, Peleg M, Cibulskis, Kristian, Ligon, Keith L, Tabernero, Josep, Seoane, Joan, Martinez-Saez, Elena, Curry, William T, Dunn, Ian F, Paek, Sun Ha, Park, Sung-Hye, McKenna, Aaron, Chevalier, Aaron, Rosenberg, Mara, Barker, 2nd, Frederick G, Gill, Corey M, Van Hummelen, Paul, Thorner, Aaron R, Johnson, Bruce E, Hoang, Mai P, Choueiri, Toni K, Signoretti, Sabina, Sougnez, Carrie, Rabin, Michael S, Lin, Nancy U, Winer, Eric P, Stemmer-Rachamimov, Anat, Meyerson, Matthew, Garraway, Levi, Gabriel, Stacey, Lander, Eric S, Beroukhim, Rameen, Batchelor, Tracy T, Baselga, Jose, Louis, David N, Getz, Gad, Hahn, William C

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HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models von Whitesell, Luke, Santagata, Sandro, Mendillo, Marc L., Lin, Nancy U., Proia, David A., Lindquist, Susan

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Updates in the management of brain metastases von Arvold, Nils D, Lee, Eudocia Q, Mehta, Minesh P, Margolin, Kim, Alexander, Brian M, Lin, Nancy U, Anders, Carey K, Soffietti, Riccardo, Camidge, D Ross, Vogelbaum, Michael A, Dunn, Ian F, Wen, Patrick Y

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Phase II study of ipilimumab and nivolumab in leptomeningeal carcinomatosis von Brastianos, Priscilla K., Strickland, Matthew R., Lee, Eudocia Quant, Wang, Nancy, Cohen, Justine V., Chukwueke, Ugonma, Forst, Deborah Anne, Eichler, April, Overmoyer, Beth, Lin, Nancy U., Chen, Wendy Y., Bardia, Aditya, Juric, Dejan, Dagogo-Jack, Ibiayi, White, Michael D., Dietrich, Jorg, Nayyar, Naema, Kim, Albert E., Alvarez-Breckenridge, Christopher, Mahar, Maura, Mora, Joana L., Nahed, Brian V., Jones, Pamela S., Shih, Helen A., Gerstner, Elizabeth R., Giobbie-Hurder, Anita, Carter, Scott L., Oh, Kevin, Cahill, Daniel P., Sullivan, Ryan J.

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Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today von Sperduto, Paul W., Mesko, Shane, Li, Jing, Cagney, Daniel, Aizer, Ayal, Lin, Nancy U., Nesbit, Eric, Kruser, Tim J., Chan, Jason, Braunstein, Steve, Lee, Jessica, Kirkpatrick, John P., Breen, Will, Brown, Paul D., Shi, Diana, Shih, Helen A., Soliman, Hany, Sahgal, Arjun, Shanley, Ryan, Sperduto, William, Lou, Emil, Everett, Ashlyn, Boggs, Drexell Hunter, Masucci, Laura, Roberge, David, Remick, Jill, Plichta, Kristin, Buatti, John M., Jain, Supriya, Gaspar, Laurie E., Wu, Cheng-Chia, Wang, Tony J.C., Bryant, John, Chuong, Michael, Yu, James, Chiang, Veronica, Nakano, Toshimichi, Aoyama, Hidefumi, Mehta, Minesh P.

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Phase 2 study of buparlisib (BKM120), a pan-class I PI3K inhibitor, in patients with metastatic triple-negative breast cancer von Garrido-Castro, Ana C, Saura, Cristina, Barroso-Sousa, Romualdo, Guo, Hao, Ciruelos, Eva, Bermejo, Begoña, Gavilá, Joaquin, Serra, Violeta, Prat, Aleix, Paré, Laia, Céliz, Pamela, Villagrasa, Patricia, Li, Yisheng, Savoie, Jennifer, Xu, Zhan, Arteaga, Carlos L, Krop, Ian E, Solit, David B, Mills, Gordon B, Cantley, Lewis C, Winer, Eric P, Lin, Nancy U, Rodon, Jordi

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Reply to J. Wei et al von Lin, Nancy U, Pegram, Mark, Sahebjam, Solmaz, Ibrahim, Nuhad, Fung, Anita, Cheng, Anna, Nicholas, Alan, Kirschbrown, Whitney, Kumthekar, Priya

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