The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans von Emerson, Felicity J., Chiu, Caitlin, Lin, Laura Y., Riedel, Christian G., Zhu, Ming, Lee, Siu Sylvia

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Misuse of Prescription Pain Relievers, Stimulants, Tranquilizers, and Sedatives Among U.S. Older Adults Aged ≥50 Years von Odani, Satomi, Lin, Laura C., Nelson, Jantel R., Agaku, Israel T.

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GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates von Breen, Danna M., Kim, Hanna, Bennett, Donald, Calle, Roberto A., Collins, Susie, Esquejo, Ryan M., He, Tao, Joaquim, Stephanie, Joyce, Alison, Lambert, Matthew, Lin, Laura, Pettersen, Betty, Qiao, Shuxi, Rossulek, Michelle, Weber, Gregory, Wu, Zhidan, Zhang, Bei B., Birnbaum, Morris J.

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RNA disruption indicates CHOP therapy efficacy in canine lymphoma von Parissenti, Amadeo M, Pritzker, Laura B, Guo, Baoqing, Narendrula, Rashmi, Wang, Shirly Xiaohui, Lin, Lin Laura, Pei, Jingchun, Skowronski, Karolina, Bienzle, Dorothee, Woods, J Paul, Pritzker, Kenneth P H, Coomber, Brenda L

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Crystal Structure of a Human IκB Kinase β Asymmetric Dimer von Liu, Shenping, Misquitta, Yohann R., Olland, Andrea, Johnson, Mark A., Kelleher, Kerry S., Kriz, Ron, Lin, Laura L., Stahl, Mark, Mosyak, Lidia

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Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design von Apgar, James R., Tam, Amy S. P., Sorm, Rhady, Moesta, Sybille, King, Amy C., Yang, Han, Kelleher, Kerry, Murphy, Denise, D'Antona, Aaron M., Yan, Guoying, Zhong, Xiaotian, Rodriguez, Linette, Ma, Weijun, Ferguson, Darren E., Carven, Gregory J., Bennett, Eric M., Lin, Laura

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Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics von Avery, Lindsay B, Wade, Jason, Wang, Mengmeng, Tam, Amy, King, Amy, Piche-Nicholas, Nicole, Kavosi, Mania S, Penn, Steve, Cirelli, David, Kurz, Jeffrey C, Zhang, Minlei, Cunningham, Orla, Jones, Rhys, Fennell, Brian J, McDonnell, Barry, Sakorafas, Paul, Apgar, James, Finlay, William J, Lin, Laura, Bloom, Laird, O'Hara, Denise M

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Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells von Shao, Esther S., Lin, Laura, Yao, Yucheng, Boström, Kristina I.

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Cysteine metabolic engineering and selective disulfide reduction produce superior antibody-drug-conjugates von Procopio-Melino, Renée, Kotch, Frank W., Prashad, Amar S., Gomes, Jose M., Wang, Wenge, Arve, Bo, Dawdy, Andrew, Chen, Lawrence, Sperry, Justin, Hosselet, Christine, He, Tao, Kriz, Ronald, Lin, Laura, Marquette, Kimberly, Tchistiakova, Lioudmila, Somers, Will, Rouse, Jason C., Zhong, Xiaotian

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Tyrosine Sulfation at Antibody Light Chain CDR-1 Increases Binding Affinity and Neutralization Potency to Interleukine-4 von D'Antona, Aaron M, Lee, Julie M, Zhang, Melvin, Friedman, Clarence, He, Tao, Mosyak, Lidia, Bennett, Eric, Lin, Laura, Silverman, Maddison, Cometa, Funi, Meade, Caryl, Hageman, Tyler, Sousa, Eric, Cohen, Justin, Marquette, Kimberly, Ferguson, Darren, Zhong, Xiaotian

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Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation von Fung, Ella, Kang, Liya, Sapashnik, Diana, Benard, Susan, Sievers, Annette, Liu, Yan, Yan, Guoying, Zhou, Jing, Rodriguez, Linette, Ma, Weijun, Stochaj, Wayne R., LaVallie, Edward, Wroblewska, Liliana, Kelleher, Kerry, Tam, Amy, Bezy, Olivier, Breen, Danna, Chabot, Jeffrey R., He, Tao, Lin, Laura, Wu, Zhidan, Mosyak, Lidia

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An inducible RIPK3-driven necroptotic system enhances cancer cell-based immunotherapy and ensures safety von Chen, Kok-Siong, Manoury-Battais, Sarah, Kanaya, Nobuhiko, Vogiatzi, Ioulia, Borges, Paulo, Kruize, Sterre J., Chen, Yi-Ching, Lin, Laura Y., Rossignoli, Filippo, Mendonca, Natalia Claire, Shah, Khalid

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Transient CHO expression platform for robust antibody production and its enhanced N‐glycan sialylation on therapeutic glycoproteins von Zhong, Xiaotian, Ma, Weijun, Meade, Caryl L., Tam, Amy S., Llewellyn, Eliza, Cornell, Richard, Cote, Kaffa, Scarcelli, John J., Marshall, Jeffrey K., Tzvetkova, Boriana, Figueroa, Bruno, DiNino, Dana, Sievers, Annette, Lee, Christopher, Guo, Jane, Mahan, Evan, Francis, Christopher, Lam, Khetemenee, D'Antona, Aaron M., Zollner, Richard, Zhu, Hongli L., Kriz, Ron, Somers, Will, Lin, Laura

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In vitro affinity optimization of an anti-BDNF monoclonal antibody translates to improved potency in targeting chronic pain states in vivo von Stack, Edwina, McMurray, Sheridan, McMurray, Gordon, Wade, Jason, Clark, Melissa, Young, Gareth, Marquette, Kim, Jain, Sadhana, Kelleher, Kerry, Chen, Ting, Lin, Qingcong, Bloom, Laird, Lin, Laura, Finlay, William, Suzuki, Rie, Cunningham, Orla

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Reduction of therapeutic antibody self-association using yeast-display selections and machine learning von Makowski, Emily K, Chen, Hongwei, Lambert, Matthew, Bennett, Eric M, Eschmann, Nicole S, Zhang, Yulei, Zupancic, Jennifer M, Desai, Alec A, Smith, Matthew D, Lou, Wenjia, Fernando, Amendra, Tully, Timothy, Gallo, Christopher J, Lin, Laura, Tessier, Peter M

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Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics von Ishino, Tetsuya, Wang, Mengmeng, Mosyak, Lidia, Tam, Amy, Duan, Weili, Svenson, Kristine, Joyce, Alison, O'Hara, Denise M., Lin, Laura, Somers, William S., Kriz, Ronald

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Addressing the Chinese food stereotype in health care von Lin, Laura C, Chang, Enchi K, He, Karen, Huang, Melody, Richards, Jeremy B.

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Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors von Root, Adam R., Guntas, Gurkan, Katragadda, Madan, Apgar, James R., Narula, Jatin, Chang, Chew Shun, Hanscom, Sara, McKenna, Matthew, Wade, Jason, Meade, Caryl, Ma, Weijun, Guo, Yongjing, Liu, Yan, Duan, Weili, Hendershot, Claire, King, Amy C., Zhang, Yan, Sousa, Eric, Tam, Amy, Benard, Susan, Yang, Han, Kelleher, Kerry, Jin, Fang, Piche-Nicholas, Nicole, Keating, Sinead E., Narciandi, Fernando, Lawrence-Henderson, Rosemary, Arai, Maya, Stochaj, Wayne R., Svenson, Kristine, Mosyak, Lidia, Lam, Khetemcnee, Francis, Christopher, Marquette, Kimberly, Wroblewska, Liliana, Zhu, H. Lily, Sheehan, Alfredo Darmanin, LaVallie, Edward R., D'Antona, Aaron M., Betts, Alison, King, Lindsay, Rosfjord, Edward, Cunningham, Orla, Lin, Laura, Sapra, Puja, Tchistiakova, Lioudmila, Mathur, Divya, Bloom, Laird

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Faster in vivo clearance of human embryonic kidney than Chinese hamster ovary cell derived protein: Role of glycan mediated clearance von Wang, Mengmeng, Ishino, Tetsuya, Joyce, Alison, Tam, Amy, Duan, Weili, Lin, Laura, Somers, William S., Kriz, Ronald, O'Hara, Denise M.

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Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5 von Mosyak, Lidia, Georgiadis, Katy, Shane, Tania, Svenson, Kristine, Hebert, Tracy, McDonagh, Thomas, Mackie, Stewart, Olland, Stephane, Lin, Laura, Zhong, Xiaotian, Kriz, Ronald, Reifenberg, Erica L., Collins‐Racie, Lisa A., Corcoran, Christopher, Freeman, Bethany, Zollner, Richard, Marvell, Tod, Vera, Matthew, Sum, Phaik‐Eng, Lavallie, Edward R., Stahl, Mark, Somers, William

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