Marketed Drugs Can Inhibit Cytochrome P450 27A1, a Potential New Target for Breast Cancer Adjuvant Therapy von Mast, Natalia, Lin, Joseph B, Pikuleva, Irina A

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SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration von Sasaki, Yo, Kakita, Hiroki, Kubota, Shunsuke, Sene, Abdoulaye, Lee, Tae Jun, Ban, Norimitsu, Dong, Zhenyu, Lin, Joseph B., Boye, Sanford L., DiAntonio, Aaron, Boye, Shannon E., Apte, Rajendra S., Milbrandt, Jeffrey

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Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1) von Mast, Natalia, Lin, Joseph B, Anderson, Kyle W, Bjorkhem, Ingemar, Pikuleva, Irina A

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Cholesterol in mouse retina originates primarily from in situ de novo biosynthesis von Lin, Joseph B., Mast, Natalia, Bederman, Ilya R., Li, Yong, Brunengraber, Henri, Björkhem, Ingemar, Pikuleva, Irina A.

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Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages von Lin, Joseph B, Mora, Amy, Wang, Tzu Jui, Santeford, Andrea, Usmani, Darksha, Ligon, Marianne M, Mysorekar, Indira U, Apte, Rajendra S

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Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum von Mast, Natalia, Anderson, Kyle W., Lin, Joseph B., Li, Yong, Turko, Illarion V., Tatsuoka, Curtis, Bjorkhem, Ingemar, Pikuleva, Irina A.

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Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration von Lin, Jonathan B, Moolani, Harsh V, Sene, Abdoulaye, Sidhu, Rohini, Kell, Pamela, Lin, Joseph B, Dong, Zhenyu, Ban, Norimitsu, Ory, Daniel S, Apte, Rajendra S

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Cell-specific Systemic Immune Signatures Associated with Treatment Burden in Neovascular Age-related Macular Degeneration von Lin, Joseph B., Santeford, Andrea, Usmani, Darksha, Shah, Aaditya V., Ruzycki, Philip A., Apte, Rajendra S.

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Aqueous Macrophages Contribute to Conserved CCL2 and CXCL10 Gradients in Uveitis von Lin, Joseph B., Pepple, Kathryn L., Concepcion, Christian, Korshunova, Yulia, Paley, Michael A., Paley, Grace L., Laurent, Jennifer, Apte, Rajendra S., Hassman, Lynn M.

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Combined SIRT3 and SIRT5 deletion is associated with inner retinal dysfunction in a mouse model of type 1 diabetes von Lin, Jonathan B., Lin, Joseph B., Chen, Howard C., Chen, Teresa, Apte, Rajendra S.

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Cholesterol Accumulation Promotes Photoreceptor Senescence and Retinal Degeneration von Terao, Ryo, Sohn, Brian S, Yamamoto, Taku, Lee, Tae Jun, Colasanti, Jason, Pfeifer, Charles W, Lin, Joseph B, Santeford, Andrea, Yamaguchi, Shinobu, Yoshida, Mitsukuni, Apte, Rajendra S

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Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis von Lin, Joseph B, Shen, Xiaolei, Pfeifer, Charles W, Shiau, Fion, Santeford, Andrea, Ruzycki, Philip A, Clark, Brian S, Liu, Qin, Huang, Andrew J W, Apte, Rajendra S

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Dysregulated CD200-CD200R signaling in early diabetes modulates microglia-mediated retinopathy von Pfeifer, Charles W, Walsh, James T, Santeford, Andrea, Lin, Joseph B, Beatty, Wandy L, Terao, Ryo, Liu, Yizhou A, Hase, Keitaro, Ruzycki, Philip A, Apte, Rajendra S

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Mapping of the Allosteric Site in Cholesterol Hydroxylase CYP46A1 for Efavirenz, a Drug That Stimulates Enzyme Activity von Anderson, Kyle W., Mast, Natalia, Hudgens, Jeffrey W., Lin, Joseph B., Turko, Illarion V., Pikuleva, Irina A.

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WNT7A/B promote choroidal neovascularization von Lin, Joseph B., Sene, Abdoulaye, Wiley, Luke A., Santeford, Andrea, Nudleman, Eric, Nakamura, Rei, Lin, Jonathan B., Moolani, Harsh V., Apte, Rajendra S.

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LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD+ depletion von Terao, Ryo, Lee, Tae Jun, Colasanti, Jason, Pfeifer, Charles W., Lin, Joseph B., Santeford, Andrea, Hase, Keitaro, Yamaguchi, Shinobu, Du, Daniel, Sohn, Brian S., Sasaki, Yo, Yoshida, Mitsukuni, Apte, Rajendra S.

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Targeting cell-type-specific, choroid-peripheral immune signaling to treat age-related macular degeneration von Lin, Joseph B, Santeford, Andrea, Colasanti, Jason J, Lee, Yoon, Shah, Aaditya V, Wang, Tzu Jui, Ruzycki, Philip A, Apte, Rajendra S

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Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function von Lee, Tae Jun, Sasaki, Yo, Ruzycki, Philip A, Ban, Norimitsu, Lin, Joseph B, Wu, Hung-Ting, Santeford, Andrea, Apte, Rajendra S

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Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis von Lin, Joseph B., Shen, Xiaolei, Pfeifer, Charles W., Shiau, Fion, Santeford, Andrea, Ruzycki, Philip A., Clark, Brian S., Liu, Qin, Huang, Andrew J. W., Apte, Rajendra S.

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Outcomes of submucosal (T1b) esophageal adenocarcinomas removed by endoscopic mucosal resection von Ballard, Darren D, Choksi, Neel, Lin, Jingmei, Choi, Eun-Young, Elmunzer, B Joseph, Appelman, Henry, Rex, Douglas K, Fatima, Hala, Kessler, William, DeWitt, John M

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