TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets von Lin, Gloria H Y, Chai, Vien, Lee, Vivian, Dodge, Karen, Truong, Tran, Wong, Mark, Johnson, Lisa D, Linderoth, Emma, Pang, Xinli, Winston, Jeff, Petrova, Penka S, Uger, Robert A, Viller, Natasja N

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Immune regulation by 4-1BB and 4-1BBL: complexities and challenges von Wang, Chao, Lin, Gloria H.Y, McPherson, Ann J, Watts, Tania H

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Choline acetyltransferase-expressing T cells are required to control chronic viral infection von Cox, Maureen A, Duncan, Gordon S, Lin, Gloria H Y, Steinberg, Benjamin E, Yu, Lisa X, Brenner, Dirk, Buckler, Luke N, Elia, Andrew J, Wakeham, Andrew C, Nieman, Brian, Dominguez-Brauer, Carmen, Elford, Alisha R, Gill, Kyle T, Kubli, Shawn P, Haight, Jillian, Berger, Thorsten, Ohashi, Pamela S, Tracey, Kevin J, Olofsson, Peder S, Mak, Tak W

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TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding von Petrova, Penka S, Viller, Natasja Nielsen, Wong, Mark, Pang, Xinli, Lin, Gloria H Y, Dodge, Karen, Chai, Vien, Chen, Hui, Lee, Vivian, House, Violetta, Vigo, Noel T, Jin, Debbie, Mutukura, Tapfuma, Charbonneau, Marilyse, Truong, Tran, Viau, Stephane, Johnson, Lisa D, Linderoth, Emma, Sievers, Eric L, Maleki Vareki, Saman, Figueredo, Rene, Pampillo, Macarena, Koropatnick, James, Trudel, Suzanne, Mbong, Nathan, Jin, Liqing, Wang, Jean C Y, Uger, Robert A

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The contextual role of TNFR family members in CD8+ T-cell control of viral infections von Wortzman, Michael E., Clouthier, Derek L., McPherson, Ann J., Lin, Gloria H. Y., Watts, Tania H.

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Evaluating the cellular targets of anti-4-1BB agonist antibody during immunotherapy of a pre-established tumor in mice von Lin, Gloria H Y, Liu, Yuanqing, Ambagala, Thanuja, Kwon, Byoung S, Ohashi, Pamela S, Watts, Tania H

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Perforin is a novel immune regulator of obesity-related insulin resistance von Revelo, Xavier S, Tsai, Sue, Lei, Helena, Luck, Helen, Ghazarian, Magar, Tsui, Hubert, Shi, Sally Y, Schroer, Stephanie, Luk, Cynthia T, Lin, Gloria H Y, Mak, Tak W, Woo, Minna, Winer, Shawn, Winer, Daniel A

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Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells von Brenner, Dirk, Brüstle, Anne, Lin, Gloria H. Y., Lang, Philipp A., Duncan, Gordon S., Knobbe-Thomsen, Christiane B., Paul, Michael St, Reardon, Colin, Tusche, Michael W., Snow, Bryan, Hamilton, Sara R., Pfefferle, Aline, Gilani, Syed O., Ohashi, Pamela S., Lang, Karl S., Mak, Tak W.

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Endogenous 4-1BB Ligand Plays a Critical Role in Protection from Influenza-Induced Disease von Lin, Gloria H. Y, Sedgmen, Bradley J, Moraes, Theo J, Snell, Laura M, Topham, David J, Watts, Tania H

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Targeting CD47-SIRPa axis shows potent preclinical anti-tumor activity as monotherapy and synergizes with PARP inhibition von Al-Sudani, Hussein, Ni, Ying, Jones, Philip, Karakilic, Huseyin, Cui, Lei, Johnson, Lisa D. S., Rose, Peter G., Olawaiye, Alexander, Edwards, Robert P., Uger, Robert A., Lin, Gloria H. Y., Mahdi, Haider

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CD8 T cell-intrinsic GITR is required for T cell clonal expansion and mouse survival following severe influenza infection von Snell, Laura M, McPherson, Ann J, Lin, Gloria H Y, Sakaguchi, Shimon, Pandolfi, Pier Paolo, Riccardi, Carlo, Watts, Tania H

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Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis von Afzal, Samia, Hao, Zhenyue, Itsumi, Momoe, Abouelkheer, Yasser, Brenner, Dirk, Gao, Yunfei, Wakeham, Andrew, Hong, Claire, Li, Wanda Y., Sylvester, Jennifer, Gilani, Syed O., Brüstle, Anne, Haight, Jillian, You-Ten, Annick J., Lin, Gloria H. Y., Inoue, Satoshi, Mak, Tak W.

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Incorporation of 4-1BB ligand into an adenovirus vaccine vector increases the number of functional antigen-specific CD8 T cells and enhances the duration of protection against infl... von Moraes, Theo J, Lin, Gloria H.Y, Wen, Tao, Watts, Tania H

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IL-15-dependent upregulation of GITR on CD8 memory phenotype T cells in the bone marrow relative to spleen and lymph node suggests the bone marrow as a site of superior bioavailabi... von Snell, Laura M, Lin, Gloria H Y, Watts, Tania H

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GITR-dependent regulation of 4-1BB expression: implications for T cell memory and anti-4-1BB-induced pathology von Lin, Gloria H Y, Snell, Laura M, Wortzman, Michael E, Clouthier, Derek L, Watts, Tania H

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Intrinsic TNF/TNFR2 interactions fine-tune the CD8 T cell response to respiratory influenza virus infection in mice von Wortzman, Michael E, Lin, Gloria H Y, Watts, Tania H

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T cell intrinsic NOD2 is dispensable for CD8 T cell immunity von Lin, Gloria H Y, Wortzman, Michael E, Girardin, Stephen E, Philpott, Dana J, Watts, Tania H

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Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection von Wang, Chao, McPherson, Ann J, Jones, R Brad, Kawamura, Kim S, Lin, Gloria H Y, Lang, Philipp A, Ambagala, Thanuja, Pellegrini, Marc, Calzascia, Thomas, Aidarus, Nasra, Elford, Alisha R, Yue, Feng Yun, Kremmer, Elisabeth, Kovacs, Colin M, Benko, Erika, Tremblay, Cecile, Routy, Jean-Pierre, Bernard, Nicole F, Ostrowski, Mario A, Ohashi, Pamela S, Watts, Tania H

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Contribution of 4–1BBL on radioresistant cells in providing survival signals through 4–1BB expressed on CD8+ memory T cells in the bone marrow von Lin, Gloria H. Y., Edele, Fanny, Mbanwi, Achire N., Wortzman, Michael E., Snell, Laura M., Vidric, Mariana, Roth, Katrin, Hauser, Anja E., Watts, Tania H.

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T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy von Snell, Laura M., Lin, Gloria H. Y., McPherson, Ann J., Moraes, Theo J., Watts, Tania H.

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